{"id":11945,"date":"2024-05-17T11:42:23","date_gmt":"2024-05-17T08:42:23","guid":{"rendered":"https:\/\/doctorvasiliadis.gr\/?page_id=11945"},"modified":"2024-05-25T19:20:56","modified_gmt":"2024-05-25T16:20:56","slug":"%ce%bc%ce%b5%ce%bb%ce%ad%cf%84%ce%b7-%ce%bf%ce%bc%ce%bf%ce%b9%cf%8c%cf%83%cf%84%ce%b1%cf%83%ce%b7%cf%82-%cf%84%ce%bf%cf%85-%ce%b3%cf%85%ce%bd%ce%b1%ce%b9%ce%ba%ce%b5%ce%af%ce%bf%cf%85-%ce%ba%cf%8c","status":"publish","type":"page","link":"https:\/\/doctorvasiliadis.gr\/?page_id=11945","title":{"rendered":"\u039c\u03b5\u03bb\u03ad\u03c4\u03b7 \u03bf\u03bc\u03bf\u03b9\u03cc\u03c3\u03c4\u03b1\u03c3\u03b7\u03c2 \u03c4\u03bf\u03c5 \u03b3\u03c5\u03bd\u03b1\u03b9\u03ba\u03b5\u03af\u03bf\u03c5 \u03ba\u03cc\u03bb\u03c0\u03bf\u03c5"},"content":{"rendered":"<div id=\"pl-11945\"  class=\"panel-layout\" ><div id=\"pg-11945-0\"  class=\"panel-grid panel-has-style\" ><div class=\"siteorigin-panels-stretch panel-row-style panel-row-style-for-11945-0\" data-stretch-type=\"full-width-stretch\" ><div id=\"pgc-11945-0-0\"  class=\"panel-grid-cell\" ><div id=\"panel-11945-0-0-0\" class=\"so-panel widget widget_sow-editor panel-first-child panel-last-child\" data-index=\"0\" ><div class=\"panel-widget-style panel-widget-style-for-11945-0-0-0\" ><div\n\t\t\t\n\t\t\tclass=\"so-widget-sow-editor so-widget-sow-editor-base\"\n\t\t\t\n\t\t>\n<div class=\"siteorigin-widget-tinymce textwidget\">\n\t<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-7410 size-full\" src=\"https:\/\/doctorvasiliadis.gr\/wp-content\/uploads\/2023\/11\/mhtra.png\" alt=\"\" width=\"800\" height=\"564\" srcset=\"https:\/\/doctorvasiliadis.gr\/wp-content\/uploads\/2023\/11\/mhtra.png 800w, https:\/\/doctorvasiliadis.gr\/wp-content\/uploads\/2023\/11\/mhtra-300x212.png 300w, https:\/\/doctorvasiliadis.gr\/wp-content\/uploads\/2023\/11\/mhtra-768x541.png 768w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/p>\n<\/div>\n<\/div><\/div><\/div><\/div><div id=\"pgc-11945-0-1\"  class=\"panel-grid-cell\" ><div id=\"panel-11945-0-1-0\" class=\"so-panel widget widget_sow-editor panel-first-child panel-last-child\" data-index=\"1\" ><div class=\"panel-widget-style panel-widget-style-for-11945-0-1-0\" ><div\n\t\t\t\n\t\t\tclass=\"so-widget-sow-editor so-widget-sow-editor-base\"\n\t\t\t\n\t\t>\n<div class=\"siteorigin-widget-tinymce textwidget\">\n\t<div class=\"part1\"><span style=\"font-size: 20px;\"><strong><span role=\"menubar\"><a role=\"menuitem\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#\" aria-expanded=\"false\" aria-haspopup=\"true\">Front Cell Infect Microbiol.\u00a0<\/a><\/span>2021;\u00a011: 686167.<\/strong><\/span><\/div>\n<div class=\"part2\"><span style=\"font-size: 20px;\"><strong><span class=\"fm-vol-iss-date\">\u0394\u03b7\u03bc\u03bf\u03c3\u03b9\u03b5\u03cd\u03b8\u03b7\u03ba\u03b5 \u03c3\u03c4\u03bf \u03b4\u03b9\u03b1\u03b4\u03af\u03ba\u03c4\u03c5\u03bf 2021, 6 \u0399\u03bf\u03c5\u03bb\u03af\u03bf\u03c5. <\/span><span class=\"doi\">doi:<a href=\"https:\/\/doi.org\/10.3389%2Ffcimb.2021.686167\" target=\"_blank\" rel=\"noopener noreferrer\">10.3389\/fcimb.2021.686167<\/a><\/span><\/strong><\/span><\/div>\n<div>\n<h1 class=\"content-title\">\u03a4\u03bf \u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03cc \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03af\u03c9\u03bc\u03b1: \u0388\u03bd\u03b1\u03c2 \u03bc\u03b1\u03ba\u03c1\u03cd\u03c2 \u03bf\u03c5\u03c1\u03bf\u03b3\u03b5\u03bd\u03bd\u03b7\u03c4\u03b9\u03ba\u03cc\u03c2 \u03b1\u03c0\u03bf\u03b9\u03ba\u03b9\u03c3\u03bc\u03cc\u03c2 \u03c3\u03b5 \u03cc\u03bb\u03b7 \u03c4\u03b7 \u03b6\u03c9\u03ae \u03c4\u03b7\u03c2 \u03b3\u03c5\u03bd\u03b1\u03af\u03ba\u03b1\u03c2<\/h1>\n<p><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/\" target=\"_blank\" rel=\"noopener\"><strong><em><span style=\"font-size: 20px;\">\u03b4\u03b9\u03b1\u03b2\u03ac\u03c3\u03c4\u03b5 \u03b5\u03b4\u03ce \u03c4\u03bf \u0391\u03b3\u03b3\u03bb\u03b9\u03ba\u03cc \u03ac\u03c1\u03b8\u03c1\u03bf<\/span><\/em><\/strong><\/a><strong><em><span style=\"font-size: 20px;\">\u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0\u00a0<\/span><\/em><\/strong><\/p>\n<h2 id=\"s1title\" class=\"head no_bottom_margin ui-helper-clearfix\"><span style=\"color: #ff0000;\">\u03a3\u03b1\u03c2 \u03c0\u03b1\u03c1\u03b1\u03b8\u03ad\u03c4\u03bf\u03c5\u03bc\u03b5 \u03c4\u03b7\u03bd \u0395\u03bb\u03bb\u03b7\u03bd\u03b9\u03ba\u03ae \u03b1\u03c0\u03cc\u03b4\u03bf\u03c3\u03b7 <\/span><\/h2>\n<h2 class=\"head no_bottom_margin ui-helper-clearfix\"><span style=\"color: #ff0000;\">\u0395\u03b9\u03c3\u03b1\u03b3\u03c9\u03b3\u03ae<\/span><\/h2>\n<p class=\"p p-first\">\u03a4\u03bf \u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03cc \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03af\u03c9\u03bc\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03ad\u03bd\u03b1 \u03c0\u03bf\u03bb\u03cd\u03c0\u03bb\u03bf\u03ba\u03bf \u03bf\u03b9\u03ba\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03cc \u03c3\u03cd\u03c3\u03c4\u03b7\u03bc\u03b1 \u03c0\u03bf\u03c5 \u03c0\u03b5\u03c1\u03b9\u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03b5\u03b9 \u03c3\u03c5\u03bc\u03b2\u03b9\u03b2\u03b1\u03c3\u03bc\u03bf\u03cd\u03c2, \u03c3\u03c5\u03bc\u03b2\u03b9\u03c9\u03c4\u03b9\u03ba\u03bf\u03cd\u03c2 \u03ba\u03b1\u03b9 \u03c0\u03b1\u03b8\u03bf\u03b3\u03cc\u03bd\u03bf\u03c5\u03c2 \u03bf\u03c1\u03b3\u03b1\u03bd\u03b9\u03c3\u03bc\u03bf\u03cd\u03c2 \u03c0\u03bf\u03c5 \u03ba\u03b1\u03c4\u03bf\u03b9\u03ba\u03bf\u03cd\u03bd \u03c3\u03c4\u03b9\u03c2 \u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03ad\u03c2 \u03b5\u03c0\u03b9\u03c6\u03ac\u03bd\u03b5\u03b9\u03b5\u03c2 \u03ba\u03b1\u03b9 \u03c3\u03c4\u03b7\u03bd \u03ba\u03bf\u03b9\u03bb\u03cc\u03c4\u03b7\u03c4\u03b1 \u03c4\u03bf\u03c5, \u03b5\u03bd\u03ce \u03b4\u03b9\u03b1\u03c4\u03b7\u03c1\u03b5\u03af \u03c4\u03b7 \u03b4\u03b9\u03ba\u03ae \u03c4\u03bf\u03c5 \u03bf\u03bc\u03bf\u03b9\u03cc\u03c3\u03c4\u03b1\u03c3\u03b7 \u03bc\u03ad\u03c3\u03c9 \u03b1\u03bc\u03bf\u03b9\u03b2\u03b1\u03af\u03b1\u03c2 \u03c3\u03c7\u03ad\u03c3\u03b7\u03c2 \u03bc\u03b5 \u03c4\u03bf\u03bd \u03be\u03b5\u03bd\u03b9\u03c3\u03c4\u03ae (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B69\" aria-expanded=\"false\" aria-haspopup=\"true\">Sobel, 1999<\/a>\u00a0).\u00a0\u0391\u03c5\u03c4\u03cc\u03c2 \u03bf \u03b2\u03b9\u03cc\u03c4\u03bf\u03c0\u03bf\u03c2 \u03ba\u03c5\u03c1\u03b9\u03b1\u03c1\u03c7\u03b5\u03af\u03c4\u03b1\u03b9 \u03c3\u03c5\u03bd\u03ae\u03b8\u03c9\u03c2 \u03b1\u03c0\u03cc \u03ad\u03bd\u03b1\u03bd \u03c0\u03b5\u03c1\u03b9\u03bf\u03c1\u03b9\u03c3\u03bc\u03ad\u03bd\u03bf \u03b1\u03c1\u03b9\u03b8\u03bc\u03cc \u03b5\u03b9\u03b4\u03ce\u03bd \u03b2\u03b1\u03ba\u03c4\u03b7\u03c1\u03af\u03c9\u03bd \u03b3\u03b1\u03bb\u03b1\u03ba\u03c4\u03b9\u03ba\u03bf\u03cd \u03bf\u03be\u03ad\u03bf\u03c2 (LAB) \u03c0\u03bf\u03c5 \u03b1\u03bd\u03c4\u03b9\u03c0\u03c1\u03bf\u03c3\u03c9\u03c0\u03b5\u03cd\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c0\u03bf\u03b9\u03ba\u03b9\u03bb\u03bf\u03c4\u03c1\u03cc\u03c0\u03c9\u03c2 \u03c3\u03c4\u03b9\u03c2 \u03b4\u03b9\u03ac\u03c6\u03bf\u03c1\u03b5\u03c2 \u03b3\u03c5\u03bd\u03b1\u03af\u03ba\u03b5\u03c2 \u03b1\u03bd\u03b1\u03c0\u03b1\u03c1\u03b1\u03b3\u03c9\u03b3\u03b9\u03ba\u03ae\u03c2 \u03b7\u03bb\u03b9\u03ba\u03af\u03b1\u03c2, \u03c4\u03b1 \u03bf\u03c0\u03bf\u03af\u03b1 \u03b4\u03c1\u03bf\u03c5\u03bd \u03c3\u03c5\u03bb\u03bb\u03bf\u03b3\u03b9\u03ba\u03ac \u03b5\u03bd\u03ac\u03bd\u03c4\u03b9\u03b1 \u03c3\u03b5 \u03b4\u03b9\u03ac\u03c6\u03bf\u03c1\u03b5\u03c2 \u03b1\u03c3\u03b8\u03ad\u03bd\u03b5\u03b9\u03b5\u03c2, \u03cc\u03c0\u03c9\u03c2 \u03bc\u03bf\u03bb\u03c5\u03c3\u03bc\u03b1\u03c4\u03b9\u03ba\u03ad\u03c2, \u03bf\u03c5\u03c1\u03bf\u03b3\u03b5\u03bd\u03bd\u03b7\u03c4\u03b9\u03ba\u03ad\u03c2 \u03ba\u03b1\u03b9 \u03bc\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03b9\u03ba\u03ad\u03c2 \u03b1\u03c3\u03b8\u03ad\u03bd\u03b5\u03b9\u03b5\u03c2 (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B60\" aria-expanded=\"false\" aria-haspopup=\"true\">Ravel et al., 2011<\/a>\u00a0).<\/p>\n<p>\u039f \u03b2\u03b9\u03cc\u03c4\u03bf\u03c0\u03bf\u03c2 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c3\u03c4\u03b5\u03bd\u03ac \u03c3\u03c5\u03bd\u03b4\u03b5\u03b4\u03b5\u03bc\u03ad\u03bd\u03bf\u03c2 \u03bc\u03b5 \u03c4\u03b7 \u03c6\u03c5\u03bb\u03ae \u03ae \u03c4\u03b7\u03bd \u03b5\u03b8\u03bd\u03b9\u03ba\u03cc\u03c4\u03b7\u03c4\u03b1 \u03c4\u03c9\u03bd \u03c5\u03c0\u03bf\u03ba\u03b5\u03b9\u03bc\u03ad\u03bd\u03c9\u03bd \u03ba\u03b1\u03b8\u03ce\u03c2 \u03ba\u03b1\u03b9 \u03bc\u03b5 \u03c0\u03c1\u03bf\u03c3\u03c9\u03c0\u03b9\u03ba\u03ad\u03c2 \u03ba\u03b1\u03b9 \u03ba\u03bf\u03b9\u03bd\u03c9\u03bd\u03b9\u03ba\u03ad\u03c2 \u03c3\u03c5\u03bc\u03c0\u03b5\u03c1\u03b9\u03c6\u03bf\u03c1\u03ad\u03c2, \u03cc\u03c0\u03c9\u03c2 \u03b4\u03b9\u03b1\u03c4\u03c1\u03bf\u03c6\u03b9\u03ba\u03ad\u03c2 \u03c3\u03c5\u03bd\u03ae\u03b8\u03b5\u03b9\u03b5\u03c2, \u03c7\u03c1\u03ae\u03c3\u03b7 \u03c0\u03c1\u03bf\u03b2\u03b9\u03bf\u03c4\u03b9\u03ba\u03ce\u03bd, \u03c5\u03b3\u03b9\u03b5\u03b9\u03bd\u03ad\u03c2 \u03ba\u03b1\u03b9 \u03c3\u03b5\u03be\u03bf\u03c5\u03b1\u03bb\u03b9\u03ba\u03ad\u03c2 \u03c0\u03c1\u03b1\u03ba\u03c4\u03b9\u03ba\u03ad\u03c2 \u03ae \u03c7\u03c1\u03ae\u03c3\u03b7 \u03bb\u03b9\u03c0\u03b1\u03bd\u03c4\u03b9\u03ba\u03ce\u03bd (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B20\" aria-expanded=\"false\" aria-haspopup=\"true\">Dur\u00e1n et al., 2020<\/a>\u00a0).<\/p>\n<p>\u03a0\u03c1\u03cc\u03c3\u03c6\u03b1\u03c4\u03b5\u03c2 \u03c0\u03c1\u03bf\u03c3\u03c0\u03ac\u03b8\u03b5\u03b9\u03b5\u03c2 \u03bc\u03b5\u03c4\u03b1\u03b3\u03bf\u03bd\u03b9\u03b4\u03b9\u03c9\u03bc\u03b1\u03c4\u03b9\u03ba\u03ce\u03bd \u03c0\u03c1\u03bf\u03c3\u03b5\u03b3\u03b3\u03af\u03c3\u03b5\u03c9\u03bd \u03b1\u03bd\u03b5\u03be\u03ac\u03c1\u03c4\u03b7\u03c4\u03c9\u03bd \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03ba\u03b1\u03bb\u03bb\u03b9\u03ad\u03c1\u03b3\u03b5\u03b9\u03b1 \u03ad\u03c7\u03bf\u03c5\u03bd \u03b5\u03bd\u03c4\u03bf\u03c0\u03af\u03c3\u03b5\u03b9 \u03c4\u03b9\u03c2 \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03b9\u03b1\u03ba\u03ad\u03c2 \u03ba\u03bf\u03b9\u03bd\u03cc\u03c4\u03b7\u03c4\u03b5\u03c2 \u03c0\u03bf\u03c5 \u03ba\u03b1\u03c4\u03bf\u03b9\u03ba\u03bf\u03cd\u03bd \u03c3\u03c4\u03bf\u03bd \u03ba\u03cc\u03bb\u03c0\u03bf (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B62\" aria-expanded=\"false\" aria-haspopup=\"true\">Relman, 2015<\/a>\u00a0).\u00a0\u0399\u03b4\u03b9\u03b1\u03af\u03c4\u03b5\u03c1\u03b1, \u03b5\u03af\u03b4\u03b7\u00a0<em>Lactobacillus<\/em>\u00a0spp.\u00a0\u03ba\u03c5\u03c1\u03b9\u03b1\u03c1\u03c7\u03bf\u03cd\u03bd \u03c3\u03c4\u03b9\u03c2 \u03c0\u03b5\u03c1\u03b9\u03c3\u03c3\u03cc\u03c4\u03b5\u03c1\u03b5\u03c2 \u03b3\u03c5\u03bd\u03b1\u03af\u03ba\u03b5\u03c2, \u03c0\u03b1\u03af\u03b6\u03bf\u03bd\u03c4\u03b1\u03c2 \u03ba\u03c1\u03af\u03c3\u03b9\u03bc\u03bf \u03c1\u03cc\u03bb\u03bf \u03c4\u03cc\u03c3\u03bf \u03c3\u03c4\u03b7\u03bd \u03c5\u03b3\u03b5\u03af\u03b1 \u03c4\u03bf\u03c5 \u03ba\u03cc\u03bb\u03c0\u03bf\u03c5 \u03cc\u03c3\u03bf \u03ba\u03b1\u03b9 \u03c3\u03c4\u03b7 \u03b3\u03c5\u03bd\u03b1\u03b9\u03ba\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ae \u03b5\u03c5\u03b5\u03be\u03af\u03b1 (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B61\" aria-expanded=\"false\" aria-haspopup=\"true\">Redondo-Lopez et al., 1990<\/a>\u00a0;\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B79\" aria-expanded=\"false\" aria-haspopup=\"true\">Witkin et al., 2007<\/a>\u00a0;\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B44\" aria-expanded=\"false\" aria-haspopup=\"true\">Martin, 2012<\/a>\u00a0).\u00a0\u03a4\u03b1 LAB \u03b5\u03af\u03bd\u03b1\u03b9 \u03c3\u03b5 \u03b8\u03ad\u03c3\u03b7 \u03bd\u03b1 \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03c5\u03bd \u03c5\u03c0\u03b5\u03c1\u03bf\u03be\u03b5\u03af\u03b4\u03b9\u03bf \u03c4\u03bf\u03c5 \u03c5\u03b4\u03c1\u03bf\u03b3\u03cc\u03bd\u03bf\u03c5 \u03ba\u03b1\u03b9 \u03b3\u03b1\u03bb\u03b1\u03ba\u03c4\u03b9\u03ba\u03cc \u03bf\u03be\u03cd, \u03bd\u03b1 \u03b4\u03b7\u03bc\u03b9\u03bf\u03c5\u03c1\u03b3\u03ae\u03c3\u03bf\u03c5\u03bd \u03ad\u03bd\u03b1 \u03cc\u03be\u03b9\u03bd\u03bf \u03bc\u03b9\u03ba\u03c1\u03bf\u03c0\u03b5\u03c1\u03b9\u03b2\u03ac\u03bb\u03bb\u03bf\u03bd \u03c9\u03c2 \u03b1\u03c0\u03cc\u03ba\u03c1\u03b9\u03c3\u03b7 \u03c3\u03c4\u03b9\u03c2 \u03b4\u03b9\u03b1\u03ba\u03c5\u03bc\u03ac\u03bd\u03c3\u03b5\u03b9\u03c2 \u03c4\u03c9\u03bd \u03b5\u03c0\u03b9\u03c0\u03ad\u03b4\u03c9\u03bd \u03bf\u03b9\u03c3\u03c4\u03c1\u03bf\u03b3\u03cc\u03bd\u03c9\u03bd \u03c3\u03c4\u03b7\u03bd \u03ba\u03c5\u03ba\u03bb\u03bf\u03c6\u03bf\u03c1\u03af\u03b1 \u03c4\u03bf\u03c5 \u03b1\u03af\u03bc\u03b1\u03c4\u03bf\u03c2, \u03bd\u03b1 \u03c0\u03c1\u03bf\u03c3\u03ba\u03bf\u03bb\u03bb\u03b7\u03b8\u03bf\u03cd\u03bd \u03c3\u03c4\u03b5\u03bd\u03ac \u03c3\u03b5 \u03b5\u03be\u03b5\u03b9\u03b4\u03b9\u03ba\u03b5\u03c5\u03bc\u03ad\u03bd\u03bf \u03b5\u03c0\u03b9\u03b8\u03ae\u03bb\u03b9\u03bf, \u03b5\u03bd\u03ce \u03bc\u03ad\u03c3\u03c9 \u03b1\u03bd\u03c4\u03b1\u03b3\u03c9\u03bd\u03b9\u03c3\u03c4\u03b9\u03ba\u03bf\u03cd \u03b1\u03c0\u03bf\u03ba\u03bb\u03b5\u03b9\u03c3\u03bc\u03bf\u03cd \u03c0\u03b5\u03c1\u03b9\u03bf\u03c1\u03af\u03b6\u03bf\u03c5\u03bd \u03c4\u03b7\u03bd \u03b1\u03bd\u03ac\u03c0\u03c4\u03c5\u03be\u03b7 \u03c4\u03c9\u03bd \u03c0\u03b5\u03c1\u03b9\u03c3\u03c3\u03cc\u03c4\u03b5\u03c1\u03c9\u03bd \u03c0\u03b1\u03b8\u03bf\u03b3\u03cc\u03bd\u03c9\u03bd, \u03c0\u03bf\u03c5 \u03b5\u03bc\u03c0\u03bb\u03ad\u03ba\u03bf\u03bd\u03c4\u03b1\u03b9 \u03b5\u03c5\u03c1\u03ad\u03c9\u03c2 \u03c3\u03b5 \u03b4\u03b9\u03ac\u03c6\u03bf\u03c1\u03b5\u03c2 \u03b3\u03c5\u03bd\u03b1\u03b9\u03ba\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ad\u03c2 \u03b4\u03b9\u03b1\u03c4\u03b1\u03c1\u03b1\u03c7\u03ad\u03c2 (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B61\" aria-expanded=\"false\" aria-haspopup=\"true\">Redondo-Lopez et al., 1990<\/a>\u00a0;\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B79\" aria-expanded=\"false\" aria-haspopup=\"true\">Witkin et al., 2007<\/a>\u00a0;\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B44\" aria-expanded=\"false\" aria-haspopup=\"true\">Martin, 2012<\/a>\u00a0).\u00a0\u038c\u03c4\u03b1\u03bd \u03c4\u03b1 \u03b5\u03c0\u03af\u03c0\u03b5\u03b4\u03b1 LAB \u03bc\u03b5\u03b9\u03ce\u03bd\u03bf\u03bd\u03c4\u03b1\u03b9, \u03c4\u03b1 \u03b1\u03bd\u03b1\u03b5\u03c1\u03cc\u03b2\u03b9\u03b1 \u03b2\u03b1\u03ba\u03c4\u03ae\u03c1\u03b9\u03b1 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b5\u03bc\u03c6\u03b1\u03bd\u03b9\u03c3\u03c4\u03bf\u03cd\u03bd \u03ba\u03b1\u03b9 \u03c3\u03c5\u03c7\u03bd\u03ac \u03ba\u03b1\u03b8\u03bf\u03c1\u03af\u03b6\u03bf\u03c5\u03bd \u03c4\u03b7 \u03b2\u03b1\u03ba\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03ae \u03ba\u03bf\u03bb\u03c0\u03af\u03c4\u03b9\u03b4\u03b1.\u00a0\u03a3\u03c4\u03b7\u03bd \u03b1\u03bd\u03b5\u03be\u03ac\u03c1\u03c4\u03b7\u03c4\u03b7 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03ba\u03b1\u03bb\u03bb\u03b9\u03ad\u03c1\u03b3\u03b5\u03b9\u03b1 \u03b1\u03be\u03b9\u03bf\u03bb\u03cc\u03b3\u03b7\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03b1\u03bd\u03b8\u03c1\u03ce\u03c0\u03b9\u03bd\u03bf\u03c5 \u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03bf\u03cd \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03b9\u03ce\u03bc\u03b1\u03c4\u03bf\u03c2,\u00a0<em>\u03c4\u03bf Prevotella<\/em>\u00a0\u03b2\u03c1\u03ad\u03b8\u03b7\u03ba\u03b5 \u03c9\u03c2 \u03ad\u03bd\u03b1 \u03b1\u03c0\u03cc \u03c4\u03b1 \u03ba\u03c5\u03c1\u03af\u03b1\u03c1\u03c7\u03b1 \u03b3\u03ad\u03bd\u03b7 (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B16\" aria-expanded=\"false\" aria-haspopup=\"true\">Diop et al., 2019<\/a>\u00a0).\u00a0<em>\u03a4\u03b1 prevotella<\/em>\u00a0\u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b1 \u03c0\u03b9\u03bf \u03b4\u03b9\u03b1\u03b4\u03b5\u03b4\u03bf\u03bc\u03ad\u03bd\u03b1 \u03b2\u03b1\u03ba\u03c4\u03ae\u03c1\u03b9\u03b1 \u03c3\u03c4\u03bf \u03b1\u03bd\u03b8\u03c1\u03ce\u03c0\u03b9\u03bd\u03bf \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03af\u03c9\u03bc\u03b1 \u03ba\u03b1\u03b9 \u03b7 \u03c0\u03bf\u03b9\u03ba\u03b9\u03bb\u03bf\u03bc\u03bf\u03c1\u03c6\u03af\u03b1 \u03ba\u03b1\u03b9 \u03bf\u03b9 \u03c0\u03b9\u03b8\u03b1\u03bd\u03bf\u03af \u03c1\u03cc\u03bb\u03bf\u03b9 \u03c4\u03bf\u03c5\u03c2 \u03ad\u03c7\u03bf\u03c5\u03bd \u03b1\u03be\u03b9\u03bf\u03bb\u03bf\u03b3\u03b7\u03b8\u03b5\u03af \u03c0\u03c1\u03cc\u03c3\u03c6\u03b1\u03c4\u03b1 (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B15\" aria-expanded=\"false\" aria-haspopup=\"true\">De Filippis et al., 2019<\/a>\u00a0).\u00a0\u03a3\u03c5\u03b3\u03ba\u03b5\u03ba\u03c1\u03b9\u03bc\u03ad\u03bd\u03b1,\u00a0<em>\u03c4\u03bf P. bivia<\/em>\u00a0\u03c3\u03c5\u03bd\u03b4\u03ad\u03b5\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03c4\u03b7\u03bd \u03c0\u03b1\u03c1\u03b1\u03b3\u03c9\u03b3\u03ae \u03b5\u03c0\u03b9\u03b8\u03b7\u03bb\u03b9\u03b1\u03ba\u03ce\u03bd \u03ba\u03c5\u03c4\u03bf\u03ba\u03b9\u03bd\u03ce\u03bd, \u03c0\u03bf\u03c5 \u03b5\u03bd\u03c4\u03bf\u03c0\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03c3\u03b5 \u03bc\u03bf\u03bb\u03c5\u03c3\u03bc\u03ad\u03bd\u03b1 \u03b2\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ac \u03b4\u03b5\u03af\u03b3\u03bc\u03b1\u03c4\u03b1 \u03ba\u03b1\u03c4\u03ac \u03c4\u03b9\u03c2 \u03b5\u03c0\u03b9\u03c0\u03bb\u03bf\u03ba\u03ad\u03c2 \u03c4\u03b7\u03c2 \u03b5\u03b3\u03ba\u03c5\u03bc\u03bf\u03c3\u03cd\u03bd\u03b7\u03c2.\u00a0\u03a3\u03c4\u03bf\u03bd \u03ba\u03cc\u03bb\u03c0\u03bf, \u03b5\u03bc\u03c6\u03b1\u03bd\u03af\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03bf\u03c1\u03b9\u03c3\u03bc\u03ad\u03bd\u03b1 \u03c0\u03b1\u03c1\u03b1\u03b4\u03b5\u03af\u03b3\u03bc\u03b1\u03c4\u03b1 \u03c3\u03c5\u03bd\u03b5\u03c1\u03b3\u03b9\u03c3\u03c4\u03b9\u03ba\u03ce\u03bd \u03c3\u03c7\u03ad\u03c3\u03b5\u03c9\u03bd, \u03cc\u03c0\u03c9\u03c2 \u03b7 \u03c0\u03b5\u03c1\u03af\u03c0\u03c4\u03c9\u03c3\u03b7 \u03c4\u03c9\u03bd\u00a0<em>P. bivia<\/em>\u00a0\u03ba\u03b1\u03b9\u00a0<em>Gardnerella vaginalis<\/em>\u00a0(\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B59\" aria-expanded=\"false\" aria-haspopup=\"true\">Randis and Ratner, 2019<\/a>\u00a0).<\/p>\n<p>\u03a4\u03bf \u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03cc \u03bc\u03b9\u03ba\u03c1\u03bf\u03c0\u03b5\u03c1\u03b9\u03b2\u03ac\u03bb\u03bb\u03bf\u03bd \u03b5\u03ba\u03c4\u03af\u03b8\u03b5\u03c4\u03b1\u03b9 \u03c3\u03b5 \u03bf\u03c5\u03c3\u03b9\u03b1\u03c3\u03c4\u03b9\u03ba\u03ad\u03c2 \u03c4\u03c1\u03bf\u03c0\u03bf\u03c0\u03bf\u03b9\u03ae\u03c3\u03b5\u03b9\u03c2 \u03ba\u03b1\u03b8' \u03cc\u03bb\u03b7 \u03c4\u03b7 \u03b4\u03b9\u03ac\u03c1\u03ba\u03b5\u03b9\u03b1 \u03c4\u03b7\u03c2 \u03b6\u03c9\u03ae\u03c2 \u03c4\u03c9\u03bd \u03b3\u03c5\u03bd\u03b1\u03b9\u03ba\u03ce\u03bd.\u00a0\u0391\u03c1\u03ba\u03b5\u03c4\u03bf\u03af \u03c3\u03c4\u03c1\u03b5\u03c3\u03bf\u03b3\u03cc\u03bd\u03bf\u03b9 \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b5\u03c2, \u03cc\u03c0\u03c9\u03c2 \u03bf\u03c1\u03bc\u03cc\u03bd\u03b5\u03c2 \u03ba\u03b1\u03b9 \u03c3\u03c5\u03bd\u03ae\u03b8\u03b5\u03b9\u03b5\u03c2, \u03bc\u03c0\u03bf\u03c1\u03bf\u03cd\u03bd \u03bd\u03b1 \u03b1\u03bb\u03bb\u03ac\u03be\u03bf\u03c5\u03bd \u03b4\u03c1\u03b1\u03bc\u03b1\u03c4\u03b9\u03ba\u03ac \u03c4\u03b7 \u03c3\u03cd\u03bd\u03b8\u03b5\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03b9\u03ce\u03bc\u03b1\u03c4\u03bf\u03c2 \u03c4\u03bf\u03c5 \u03ba\u03cc\u03bb\u03c0\u03bf\u03c5, \u03bc\u03b5 \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1, \u03b3\u03b9\u03b1 \u03c0\u03b1\u03c1\u03ac\u03b4\u03b5\u03b9\u03b3\u03bc\u03b1, \u03c4\u03b7\u03bd \u03b5\u03be\u03ac\u03bd\u03c4\u03bb\u03b7\u03c3\u03b7 \u03c4\u03bf\u03c5 LAB, \u03c4\u03b7 \u03bc\u03b5\u03af\u03c9\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03b9\u03b1\u03ba\u03ae\u03c2 \u03c0\u03bf\u03b9\u03ba\u03b9\u03bb\u03cc\u03c4\u03b7\u03c4\u03b1\u03c2 \u03ba\u03b1\u03b9 \u03c4\u03b7\u03bd \u03b5\u03bc\u03c6\u03ac\u03bd\u03b9\u03c3\u03b7 \u03b4\u03c5\u03c3\u03b2\u03af\u03c9\u03c3\u03b7\u03c2, \u03c0\u03bf\u03c5 \u03c3\u03c5\u03c7\u03bd\u03ac \u03bf\u03b4\u03b7\u03b3\u03b5\u03af \u03c3\u03b5 \u03b2\u03b1\u03ba\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03ae \u03ba\u03bf\u03bb\u03c0\u03af\u03c4\u03b9\u03b4\u03b1, \u03bb\u03bf\u03b9\u03bc\u03ce\u03be\u03b5\u03b9\u03c2 \u03b6\u03cd\u03bc\u03b7\u03c2, \u03c3\u03b5\u03be\u03bf\u03c5\u03b1\u03bb\u03b9\u03ba\u03ac \u03bc\u03b5\u03c4\u03b1\u03b4\u03b9\u03b4\u03cc\u03bc\u03b5\u03bd\u03b1 \u03bd\u03bf\u03c3\u03ae\u03bc\u03b1\u03c4\u03b1, \u03bb\u03bf\u03b9\u03bc\u03ce\u03be\u03b5\u03b9\u03c2 \u03c4\u03bf\u03c5 \u03bf\u03c5\u03c1\u03bf\u03c0\u03bf\u03b9\u03b7\u03c4\u03b9\u03ba\u03bf\u03cd \u03c3\u03c5\u03c3\u03c4\u03ae\u03bc\u03b1\u03c4\u03bf\u03c2 \u03ba\u03b1\u03b9 \u03c6\u03c4\u03c9\u03c7\u03ae \u03b3\u03bf\u03bd\u03b9\u03bc\u03cc\u03c4\u03b7\u03c4\u03b1 (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B58\" aria-expanded=\"false\" aria-haspopup=\"true\">Pybus and Onderdonk, 1999<\/a>\u00a0;\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B18\" aria-expanded=\"false\" aria-haspopup=\"true\">Donders et al., 2000<\/a>\u00a0;\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B42\" aria-expanded=\"false\" aria-haspopup=\"true\">Marrazzo, 2006<\/a>\u00a0).\u00a0\u0397 \u03b4\u03b9\u03b1\u03c4\u03c1\u03bf\u03c6\u03b9\u03ba\u03ae \u03c0\u03c1\u03cc\u03c3\u03bb\u03b7\u03c8\u03b7 \u03ad\u03c7\u03b5\u03b9 \u03b1\u03c0\u03bf\u03b4\u03b5\u03b9\u03c7\u03b8\u03b5\u03af \u03cc\u03c4\u03b9 \u03b5\u03c0\u03b7\u03c1\u03b5\u03ac\u03b6\u03b5\u03b9 \u03c4\u03b7 \u03c3\u03cd\u03bd\u03b8\u03b5\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03bf\u03cd \u03bc\u03b9\u03ba\u03c1\u03bf\u03c0\u03b5\u03c1\u03b9\u03b2\u03ac\u03bb\u03bb\u03bf\u03bd\u03c4\u03bf\u03c2 \u03c3\u03b5 \u03b3\u03c5\u03bd\u03b1\u03af\u03ba\u03b5\u03c2 \u03b1\u03bd\u03b1\u03c0\u03b1\u03c1\u03b1\u03b3\u03c9\u03b3\u03b9\u03ba\u03ae\u03c2 \u03b7\u03bb\u03b9\u03ba\u03af\u03b1\u03c2, \u03ba\u03b1\u03b8\u03ce\u03c2 \u03b7 \u03c7\u03b1\u03bc\u03b7\u03bb\u03cc\u03c4\u03b5\u03c1\u03b7 \u03c3\u03c5\u03b3\u03ba\u03ad\u03bd\u03c4\u03c1\u03c9\u03c3\u03b7 \u03bf\u03c1\u03b9\u03c3\u03bc\u03ad\u03bd\u03c9\u03bd \u03b2\u03b1\u03c3\u03b9\u03ba\u03ce\u03bd \u03b8\u03c1\u03b5\u03c0\u03c4\u03b9\u03ba\u03ce\u03bd \u03c3\u03c5\u03c3\u03c4\u03b1\u03c4\u03b9\u03ba\u03ce\u03bd, \u03cc\u03c0\u03c9\u03c2 \u03bf\u03b9 \u03b2\u03b9\u03c4\u03b1\u03bc\u03af\u03bd\u03b5\u03c2 A, C \u03ba\u03b1\u03b9 E, \u03b7 \u03b1\u03bd\u03b5\u03c0\u03ac\u03c1\u03ba\u03b5\u03b9\u03b1 \u03b2-\u03ba\u03b1\u03c1\u03bf\u03c4\u03af\u03bd\u03b7\u03c2 \u03ba\u03b1\u03b9 \u03b7 \u03b1\u03bb\u03bb\u03bf\u03b9\u03c9\u03bc\u03ad\u03bd\u03b7 \u03ba\u03b1\u03c4\u03ac\u03c3\u03c4\u03b1\u03c3\u03b7 \u03c3\u03b9\u03b4\u03ae\u03c1\u03bf\u03c5 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03c3\u03c5\u03bc\u03b2\u03ac\u03bb\u03bb\u03bf\u03c5\u03bd \u03c3\u03c4\u03bf\u03bd \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf \u03b2\u03b1\u03ba\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03ae\u03c2 \u03ba\u03bf\u03bb\u03c0\u03af\u03c4\u03b9\u03b4\u03b1\u03c2 \u03ba\u03b1\u03b9 \u03b1\u03c0\u03bf\u03b9\u03ba\u03b9\u03c3\u03bc\u03bf\u03cd Candida.\u00a0\u03a3\u03b5 \u03c0\u03b1\u03c1\u03cc\u03bc\u03bf\u03b9\u03bf \u03b2\u03b1\u03b8\u03bc\u03cc, \u03c4\u03b1 \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03b1 \u03b5\u03c0\u03af\u03c0\u03b5\u03b4\u03b1 \u03b3\u03bb\u03c5\u03ba\u03cc\u03b6\u03b7\u03c2 \u03c3\u03c4\u03bf \u03c0\u03bb\u03ac\u03c3\u03bc\u03b1 \u03ba\u03b1\u03b9 \u03c4\u03bf \u03b4\u03b9\u03b1\u03b9\u03c4\u03b7\u03c4\u03b9\u03ba\u03cc \u03bb\u03af\u03c0\u03bf\u03c2, \u03ba\u03b1\u03b8\u03ce\u03c2 \u03ba\u03b1\u03b9 \u03b7 \u03c0\u03b1\u03c7\u03c5\u03c3\u03b1\u03c1\u03ba\u03af\u03b1, \u03c3\u03c7\u03b5\u03c4\u03af\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03c6\u03c4\u03c9\u03c7\u03cc\u03c4\u03b5\u03c1\u03b7 \u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03ae \u03c5\u03b3\u03b5\u03af\u03b1 \u03ba\u03b1\u03b9 \u03ba\u03b1\u03c4\u03ac\u03c3\u03c4\u03b1\u03c3\u03b7 \u03b4\u03c5\u03c3\u03b2\u03af\u03c9\u03c3\u03b7\u03c2 (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B20\" aria-expanded=\"false\" aria-haspopup=\"true\">Dur\u00e1n et al., 2020<\/a>\u00a0).\u00a0\u03a9\u03c3\u03c4\u03cc\u03c3\u03bf, \u03bc\u03b9\u03b1 \u03c0\u03c1\u03cc\u03c3\u03c6\u03b1\u03c4\u03b7 \u03c0\u03c1\u03bf\u03bf\u03c0\u03c4\u03b9\u03ba\u03ae \u03bc\u03b5\u03bb\u03ad\u03c4\u03b7 \u03ba\u03bf\u03cc\u03c1\u03c4\u03b7\u03c2 \u03c0\u03bf\u03c5 \u03b4\u03b9\u03b5\u03c1\u03b5\u03c5\u03bd\u03ac \u03c4\u03b7 \u03c3\u03c7\u03ad\u03c3\u03b7 \u03bc\u03b5\u03c4\u03b1\u03be\u03cd \u03c4\u03bf\u03c5 \u0394\u039c\u03a3 \u03ba\u03b1\u03b9 \u03c4\u03b7\u03c2 \u03c0\u03b5\u03c1\u03b9\u03c3\u03c4\u03b1\u03c4\u03b9\u03ba\u03ae\u03c2 \u03b2\u03b1\u03ba\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03ae\u03c2 \u03ba\u03bf\u03bb\u03c0\u03af\u03c4\u03b9\u03b4\u03b1\u03c2 \u03ad\u03c7\u03b5\u03b9 \u03c0\u03c1\u03bf\u03c4\u03b5\u03af\u03bd\u03b5\u03b9 \u03cc\u03c4\u03b9 \u03bf\u03b9 \u03c0\u03b1\u03c7\u03cd\u03c3\u03b1\u03c1\u03ba\u03b5\u03c2 \u03b3\u03c5\u03bd\u03b1\u03af\u03ba\u03b5\u03c2 \u03b5\u03af\u03c7\u03b1\u03bd \u03c7\u03b1\u03bc\u03b7\u03bb\u03cc\u03c4\u03b5\u03c1\u03bf \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf \u03b2\u03b1\u03ba\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03ae\u03c2 \u03ba\u03bf\u03bb\u03c0\u03af\u03c4\u03b9\u03b4\u03b1\u03c2 \u03c3\u03b5 \u03c3\u03cd\u03b3\u03ba\u03c1\u03b9\u03c3\u03b7 \u03bc\u03b5 \u03c4\u03b9\u03c2 \u03b3\u03c5\u03bd\u03b1\u03af\u03ba\u03b5\u03c2 \u03bc\u03b5 \u03c6\u03c5\u03c3\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03cc \u0394\u039c\u03a3 (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B41\" aria-expanded=\"false\" aria-haspopup=\"true\">Lokken et al., 2010<\/a>\u00a0).\u00a0\u039f\u03bc\u03bf\u03af\u03c9\u03c2, \u03bf\u03b9 \u03c3\u03c5\u03bd\u03ae\u03b8\u03b5\u03b9\u03b5\u03c2 \u03ba\u03b1\u03c0\u03bd\u03af\u03c3\u03bc\u03b1\u03c4\u03bf\u03c2 \u03ad\u03c7\u03bf\u03c5\u03bd \u03b2\u03c1\u03b5\u03b8\u03b5\u03af \u03bd\u03b1 \u03c3\u03c7\u03b5\u03c4\u03af\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03b2\u03b1\u03ba\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03ae \u03ba\u03bf\u03bb\u03c0\u03af\u03c4\u03b9\u03b4\u03b1, \u03bb\u03cc\u03b3\u03c9 \u03c7\u03b1\u03bc\u03b7\u03bb\u03cc\u03c4\u03b5\u03c1\u03bf\u03c5 \u03b1\u03c1\u03b9\u03b8\u03bc\u03bf\u03cd\u00a0<em>\u03b3\u03b1\u03bb\u03b1\u03ba\u03c4\u03bf\u03b2\u03b1\u03ba\u03af\u03bb\u03bb\u03c9\u03bd<\/em>\u00a0\u03ba\u03b1\u03b9 \u03c5\u03c8\u03b7\u03bb\u03cc\u03c4\u03b5\u03c1\u03c9\u03bd \u03b2\u03b1\u03b8\u03bc\u03bf\u03bb\u03bf\u03b3\u03b9\u03ce\u03bd Nugent (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B20\" aria-expanded=\"false\" aria-haspopup=\"true\">Dur\u00e1n et al., 2020<\/a>\u00a0).<\/p>\n<p>\u0397 \u03ba\u03b1\u03bb\u03cd\u03c4\u03b5\u03c1\u03b7 \u03ba\u03b1\u03c4\u03b1\u03bd\u03cc\u03b7\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03c3\u03cd\u03bd\u03b8\u03b5\u03c3\u03b7\u03c2, \u03c4\u03c9\u03bd \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03b9\u03ce\u03bd \u03ba\u03b1\u03b9 \u03c4\u03c9\u03bd \u03b1\u03bb\u03bb\u03b1\u03b3\u03ce\u03bd \u03c4\u03bf\u03c5 \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03b9\u03ce\u03bc\u03b1\u03c4\u03bf\u03c2 \u03c4\u03bf\u03c5 \u03ba\u03cc\u03bb\u03c0\u03bf\u03c5 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03ba\u03b1\u03b8\u03bf\u03c1\u03b9\u03c3\u03c4\u03b9\u03ba\u03ae\u03c2 \u03c3\u03b7\u03bc\u03b1\u03c3\u03af\u03b1\u03c2 \u03b3\u03b9\u03b1 \u03c4\u03b7\u03bd \u03b1\u03c0\u03cc\u03ba\u03c4\u03b7\u03c3\u03b7 \u03bd\u03ad\u03c9\u03bd \u03c0\u03b1\u03b8\u03bf\u03c6\u03c5\u03c3\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ce\u03bd \u03b3\u03bd\u03ce\u03c3\u03b5\u03c9\u03bd \u03c3\u03c7\u03b5\u03c4\u03b9\u03ba\u03ac \u03bc\u03b5 \u03c4\u03b9\u03c2 \u03b3\u03c5\u03bd\u03b1\u03b9\u03ba\u03b5\u03af\u03b5\u03c2 \u03b1\u03c3\u03b8\u03ad\u03bd\u03b5\u03b9\u03b5\u03c2 \u03c0\u03bf\u03c5 \u03b8\u03b1 \u03bc\u03c0\u03bf\u03c1\u03bf\u03cd\u03c3\u03b1\u03bd \u03bd\u03b1 \u03c7\u03c1\u03b7\u03c3\u03b9\u03bc\u03bf\u03c0\u03bf\u03b9\u03b7\u03b8\u03bf\u03cd\u03bd \u03b3\u03b9\u03b1 \u03c4\u03b7\u03bd \u03b5\u03c6\u03b1\u03c1\u03bc\u03bf\u03b3\u03ae \u03c3\u03c4\u03c1\u03b1\u03c4\u03b7\u03b3\u03b9\u03ba\u03ce\u03bd \u03c0\u03c1\u03cc\u03bb\u03b7\u03c8\u03b7\u03c2.<\/p>\n<p class=\"p p-last\">\u0395\u03b4\u03ce \u03c0\u03b1\u03c1\u03ad\u03c7\u03bf\u03c5\u03bc\u03b5 \u03bc\u03b9\u03b1 \u03ad\u03c1\u03b5\u03c5\u03bd\u03b1 \u03c4\u03b7\u03c2 \u03c3\u03cd\u03bd\u03b8\u03b5\u03c3\u03b7\u03c2 \u03c4\u03bf\u03c5 \u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03bf\u03cd \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03b9\u03ce\u03bc\u03b1\u03c4\u03bf\u03c2 \u03c3\u03b5 \u03cc\u03bb\u03b7 \u03c4\u03b7 \u03b4\u03b9\u03ac\u03c1\u03ba\u03b5\u03b9\u03b1 \u03c4\u03b7\u03c2 \u03b6\u03c9\u03ae\u03c2 \u03c4\u03b7\u03c2 \u03b3\u03c5\u03bd\u03b1\u03af\u03ba\u03b1\u03c2, \u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03bf\u03bd\u03c4\u03b1\u03c2 \u03c5\u03c0\u03cc\u03c8\u03b7 \u03cc\u03c4\u03b9 \u03b1\u03bb\u03bb\u03ac\u03b6\u03b5\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b7 \u03b3\u03ad\u03bd\u03bd\u03b7\u03c3\u03b7, \u03ba\u03b1\u03c4\u03ac \u03c4\u03b7\u03bd \u03b5\u03c6\u03b7\u03b2\u03b5\u03af\u03b1, \u03c4\u03b7\u03bd \u03b1\u03bd\u03b1\u03c0\u03b1\u03c1\u03b1\u03b3\u03c9\u03b3\u03b9\u03ba\u03ae \u03b7\u03bb\u03b9\u03ba\u03af\u03b1 \u03ba\u03b1\u03b9 \u03c4\u03b7\u03bd \u03b5\u03bc\u03bc\u03b7\u03bd\u03cc\u03c0\u03b1\u03c5\u03c3\u03b7.\u00a0\u0395\u03c0\u03b9\u03c0\u03bb\u03ad\u03bf\u03bd, \u03b5\u03c0\u03b9\u03c3\u03b7\u03bc\u03b1\u03af\u03bd\u03bf\u03c5\u03bc\u03b5 \u03c0\u03ce\u03c2 \u03bf\u03b9 \u03b1\u03bb\u03bb\u03b1\u03b3\u03ad\u03c2 \u03c3\u03c4\u03b7 \u03c3\u03cd\u03bd\u03b8\u03b5\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03b9\u03ce\u03bc\u03b1\u03c4\u03bf\u03c2 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b5\u03c0\u03b7\u03c1\u03b5\u03ac\u03c3\u03bf\u03c5\u03bd \u03ba\u03c1\u03af\u03c3\u03b9\u03bc\u03b1 \u03c4\u03b7\u03bd \u03c5\u03b3\u03b5\u03af\u03b1 \u03c4\u03b7\u03c2 \u03b3\u03c5\u03bd\u03b1\u03af\u03ba\u03b1\u03c2.<\/p>\n<h2 id=\"s2title\" class=\"head no_bottom_margin ui-helper-clearfix\"><span style=\"color: #ff0000;\"><strong>\u0391\u03c0\u03cc \u03bd\u03b5\u03bf\u03b3\u03ad\u03bd\u03bd\u03b7\u03c4\u03bf \u03c3\u03c4\u03b7 \u03b5\u03bc\u03bc\u03b7\u03bd\u03b1\u03c1\u03c7\u03ae<\/strong><\/span><\/h2>\n<p>\u03a0\u03bf\u03bb\u03bb\u03ac \u03b5\u03af\u03b4\u03b7 \u03b2\u03b1\u03ba\u03c4\u03b7\u03c1\u03af\u03c9\u03bd \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03bf\u03cd\u03bd \u03c4\u03bf \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03af\u03c9\u03bc\u03b1 \u03c4\u03bf\u03c5 \u03ba\u03cc\u03bb\u03c0\u03bf\u03c5 \u03c3\u03c4\u03b7\u03bd \u03c0\u03c1\u03ce\u03b9\u03bc\u03b7 \u03c0\u03b1\u03b9\u03b4\u03b9\u03ba\u03ae \u03b7\u03bb\u03b9\u03ba\u03af\u03b1 (<a class=\"fig-table-link figpopup\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/figure\/f1\/\" target=\"figure\" rel=\"noopener\"><strong>\u03a6\u03b9\u03b3\u03bf\u03cd\u03c1\u03b1 1<\/strong><\/a>), \u03c3\u03c5\u03bc\u03c0\u03b5\u03c1\u03b9\u03bb\u03b1\u03bc\u03b2\u03b1\u03bd\u03bf\u03bc\u03ad\u03bd\u03c9\u03bd \u03c4\u03c9\u03bd \u03b1\u03bd\u03b1\u03b5\u03c1\u03cc\u03b2\u03b9\u03c9\u03bd,\u00a0<em>\u0394\u03b9\u03c6\u03b8\u03b5\u03c1\u03bf\u03b5\u03b9\u03b4\u03ae<\/em>\u00a0(\u03b9\u03b4\u03b9\u03b1\u03af\u03c4\u03b5\u03c1\u03b1\u00a0<em>Corynebacterium<\/em>\u00a0spp.) \u03b1\u03c1\u03bd\u03b7\u03c4\u03b9\u03ba\u03ce\u03bd \u03c3\u03b5 \u03ba\u03bf\u03b1\u03b3\u03bf\u03c5\u03bb\u03ac\u03c3\u03b7\u00a0<em>\u03a3\u03c4\u03b1\u03c6\u03c5\u03bb\u03cc\u03ba\u03bf\u03ba\u03ba\u03bf\u03c5\u03c2<\/em>\u00a0,\u00a0<em>\u0395. coli<\/em>\u00a0\u03ba\u03b1\u03b9\u00a0<em>Mycoplasma<\/em>\u00a0spp (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B29\" aria-expanded=\"false\" aria-haspopup=\"true\">Hammerschlag et al., 1978a<\/a>\u00a0,\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B30\" aria-expanded=\"false\" aria-haspopup=\"true\">Hammerschlag et al., 1978b<\/a>\u00a0).\u00a0\u0391\u03bd\u03c4\u03af\u03b8\u03b5\u03c4\u03b1, \u03ba\u03b1\u03c4\u03ac \u03c4\u03b7\u03bd \u03ad\u03ba\u03b8\u03b5\u03c3\u03b7 \u03c3\u03b5 \u03bf\u03b9\u03c3\u03c4\u03c1\u03bf\u03b3\u03cc\u03bd\u03b1\/\u03c0\u03c1\u03bf\u03b3\u03b5\u03c3\u03c4\u03af\u03bd\u03b7 \u03bc\u03b5 \u03c4\u03b7\u03bd \u03b5\u03c6\u03b7\u03b2\u03b5\u03af\u03b1 (<a class=\"fig-table-link figpopup\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/figure\/f1\/\" target=\"figure\" rel=\"noopener\"><strong>\u03a6\u03b9\u03b3\u03bf\u03cd\u03c1\u03b1 1<\/strong><\/a>), \u03b7 \u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03ae \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03b9\u03b1\u03ba\u03ae \u03b8\u03ad\u03c3\u03b7 \u03bc\u03b5\u03c4\u03b1\u03c4\u03bf\u03c0\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03c0\u03c1\u03bf\u03c2 \u03ac\u03bb\u03bb\u03b5\u03c2 \u03ba\u03c5\u03c1\u03af\u03b1\u03c1\u03c7\u03b5\u03c2 \u03b1\u03c0\u03bf\u03b9\u03ba\u03af\u03b5\u03c2, \u03cc\u03c0\u03c9\u03c2\u00a0<em>Lactobacillus<\/em>\u00a0spp.,\u00a0<em>Atopobium<\/em>\u00a0\u03ba\u03b1\u03b9\u00a0<em>Streptococcus<\/em>\u00a0spp (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B20\" aria-expanded=\"false\" aria-haspopup=\"true\">Dur\u00e1n et al., 2020<\/a>\u00a0).<\/p>\n<div><span style=\"font-family: helvetica, arial, sans-serif; font-size: 14px;\"><em><a class=\"figpopup\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/figure\/f1\/\" target=\"figure\" rel=\"noopener\">\u03a6\u03b9\u03b3\u03bf\u03cd\u03c1\u03b1 1<\/a><\/em><\/span><\/div>\n<div class=\"caption\">\n<p><span style=\"font-family: helvetica, arial, sans-serif; font-size: 14px;\"><em>\u0391\u03bb\u03bb\u03b1\u03b3\u03ad\u03c2 \u03c3\u03c4\u03b7 \u03c3\u03cd\u03bd\u03b8\u03b5\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03b9\u03ce\u03bc\u03b1\u03c4\u03bf\u03c2 \u03c4\u03bf\u03c5 \u03ba\u03cc\u03bb\u03c0\u03bf\u03c5 \u03c3\u03b5 \u03cc\u03bb\u03b7 \u03c4\u03b7 \u03b4\u03b9\u03ac\u03c1\u03ba\u03b5\u03b9\u03b1 \u03c4\u03b7\u03c2 \u03b6\u03c9\u03ae\u03c2 \u03c4\u03b7\u03c2 \u03b3\u03c5\u03bd\u03b1\u03af\u03ba\u03b1\u03c2.\u00a0\u03a3\u03c4\u03b7\u03bd \u03c0\u03b1\u03b9\u03b4\u03b9\u03ba\u03ae \u03b7\u03bb\u03b9\u03ba\u03af\u03b1 (\u03b1\u03c1\u03b9\u03c3\u03c4\u03b5\u03c1\u03cc \u03c0\u03bb\u03b1\u03af\u03c3\u03b9\u03bf),\u00a0\u03c4\u03bf Corynebacterium\u00a0spp., \u03c4\u03bf \u03b1\u03c1\u03bd\u03b7\u03c4\u03b9\u03ba\u03cc \u03c3\u03c4\u03b7\u03bd \u03ba\u03bf\u03b1\u03b3\u03ba\u03bf\u03c5\u03bb\u03ac\u03c3\u03b7\u00a0Staphylococcus\u00a0spp.,\u00a0\u03c4\u03bf Escherichia coli\u00a0\u03ba\u03b1\u03b9\u00a0\u03c4\u03bf Mycoplasma\u00a0spp., \u03c3\u03c7\u03b7\u03bc\u03b1\u03c4\u03af\u03b6\u03bf\u03c5\u03bd \u03c4\u03bf \u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03cc \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03af\u03c9\u03bc\u03b1.\u00a0\u03a3\u03c4\u03b7\u03bd \u03b5\u03c6\u03b7\u03b2\u03b5\u03af\u03b1, \u03bc\u03b5 \u03c4\u03b7\u03bd \u03ad\u03ba\u03b8\u03b5\u03c3\u03b7 \u03c3\u03b5 \u03bf\u03b9\u03c3\u03c4\u03c1\u03bf\u03b3\u03cc\u03bd\u03b1\/\u03c0\u03c1\u03bf\u03b3\u03b5\u03c3\u03c4\u03af\u03bd\u03b7, \u03b7 \u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03ae \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03b9\u03b1\u03ba\u03ae \u03b8\u03ad\u03c3\u03b7 \u03bc\u03b5\u03c4\u03b1\u03c4\u03bf\u03c0\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03c0\u03c1\u03bf\u03c2 \u03ac\u03bb\u03bb\u03b5\u03c2 \u03ba\u03c5\u03c1\u03af\u03b1\u03c1\u03c7\u03b5\u03c2 \u03b1\u03c0\u03bf\u03b9\u03ba\u03af\u03b5\u03c2, \u03ba\u03c5\u03c1\u03af\u03c9\u03c2 \u03c3\u03c5\u03bc\u03c0\u03b5\u03c1\u03b9\u03bb\u03b1\u03bc\u03b2\u03b1\u03bd\u03bf\u03bc\u03ad\u03bd\u03c9\u03bd \u03c4\u03c9\u03bd\u00a0Lactobacillus\u00a0spp.,\u00a0Atopobium\u00a0\u03ba\u03b1\u03b9\u00a0Streptococcus\u00a0spp.\u00a0\u039a\u03b1\u03c4\u03ac \u03c4\u03b7\u03bd \u03b1\u03bd\u03b1\u03c0\u03b1\u03c1\u03b1\u03b3\u03c9\u03b3\u03b9\u03ba\u03ae \u03b7\u03bb\u03b9\u03ba\u03af\u03b1 (\u03bc\u03b5\u03c3\u03b1\u03af\u03bf \u03c0\u03bb\u03b1\u03af\u03c3\u03b9\u03bf), \u03c4\u03bf \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03af\u03c9\u03bc\u03b1 \u03c4\u03bf\u03c5 \u03ba\u03cc\u03bb\u03c0\u03bf\u03c5 \u03c6\u03b9\u03bb\u03bf\u03be\u03b5\u03bd\u03b5\u03af \u03bc\u03b9\u03b1 \u03c3\u03b5\u03b9\u03c1\u03ac \u03b1\u03c0\u03cc \u03b2\u03b1\u03ba\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03ad\u03c2 \u03ba\u03bf\u03b9\u03bd\u03cc\u03c4\u03b7\u03c4\u03b5\u03c2, \u03ba\u03c5\u03c1\u03af\u03c9\u03c2 \u03c3\u03c5\u03bc\u03c0\u03b5\u03c1\u03b9\u03bb\u03b1\u03bc\u03b2\u03b1\u03bd\u03bf\u03bc\u03ad\u03bd\u03c9\u03bd \u03c4\u03c9\u03bd \u03b3\u03b1\u03bb\u03b1\u03ba\u03c4\u03bf\u03b2\u03ac\u03ba\u03b9\u03bb\u03bb\u03c9\u03bd (\u00a0L. crispatus, L. gasseri, L. jensenii \u03ba\u03b1\u03b9 L. iners\u00a0) \u03bc\u03b1\u03b6\u03af \u03bc\u03b5 \u03b1\u03bd\u03b1\u03b5\u03c1\u03cc\u03b2\u03b9\u03b1 \u03b2\u03b1\u03ba\u03c4\u03ae\u03c1\u03b9\u03b1.\u00a0\u0397 \u03b5\u03bc\u03bc\u03b7\u03bd\u03cc\u03c0\u03b1\u03c5\u03c3\u03b7 (\u03b4\u03b5\u03be\u03b9\u03cc \u03c0\u03bb\u03b1\u03af\u03c3\u03b9\u03bf) \u03c0\u03c1\u03bf\u03ba\u03b1\u03bb\u03b5\u03af \u03c0\u03b5\u03c1\u03b1\u03b9\u03c4\u03ad\u03c1\u03c9 \u03b1\u03bb\u03bb\u03b1\u03b3\u03ad\u03c2 \u03c3\u03c4\u03b7 \u03c3\u03cd\u03bd\u03b8\u03b5\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03b9\u03ce\u03bc\u03b1\u03c4\u03bf\u03c2 \u03c4\u03bf\u03c5 \u03ba\u03cc\u03bb\u03c0\u03bf\u03c5, \u03c0\u03bf\u03c5 \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03af\u03c4\u03b1\u03b9 \u03ba\u03c5\u03c1\u03af\u03c9\u03c2 \u03b1\u03c0\u03cc\u00a0Gardnerella vaginalis\u00a0,\u00a0Ureaplasma urealyticum\u00a0,\u00a0Candida albicans\u00a0\u03ba\u03b1\u03b9\u00a0Prevotella\u00a0spp., \u03bc\u03b1\u03b6\u03af \u03bc\u03b5 \u03c0\u03c1\u03bf\u03bf\u03b4\u03b5\u03c5\u03c4\u03b9\u03ba\u03ae \u03bc\u03b5\u03af\u03c9\u03c3\u03b7 \u03c4\u03c9\u03bd \u03b5\u03b9\u03b4\u03ce\u03bd\u00a0Lactobacillus\u00a0.\u00a0\u0394\u03b7\u03bc\u03b9\u03bf\u03c5\u03c1\u03b3\u03ae\u03b8\u03b7\u03ba\u03b5 \u03bc\u03b5\u00a0<a href=\"https:\/\/biorender.com\/\">\u03c4\u03bf BioRender.com<\/a>\u00a0.<\/em><\/span><\/p>\n<p>\u0399\u03c3\u03c4\u03bf\u03c1\u03b9\u03ba\u03ac, \u03ad\u03c7\u03b5\u03b9 \u03b8\u03b5\u03c9\u03c1\u03b7\u03b8\u03b5\u03af \u03cc\u03c4\u03b9 \u03c4\u03bf \u03ad\u03bc\u03b2\u03c1\u03c5\u03bf \u03b1\u03bd\u03b1\u03c0\u03c4\u03cd\u03c3\u03c3\u03b5\u03c4\u03b1\u03b9 \u03c3\u03b5 \u03c3\u03c4\u03b5\u03af\u03c1\u03bf \u03c0\u03b5\u03c1\u03b9\u03b2\u03ac\u03bb\u03bb\u03bf\u03bd \u03ba\u03b1\u03c4\u03ac \u03c4\u03b7 \u03b4\u03b9\u03ac\u03c1\u03ba\u03b5\u03b9\u03b1 \u03c4\u03b7\u03c2 \u03b5\u03b3\u03ba\u03c5\u03bc\u03bf\u03c3\u03cd\u03bd\u03b7\u03c2 (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B72\" aria-expanded=\"false\" aria-haspopup=\"true\">Tamburini et al., 2016<\/a>\u00a0).\u00a0\u03a9\u03c3\u03c4\u03cc\u03c3\u03bf, \u03c0\u03c1\u03cc\u03c3\u03c6\u03b1\u03c4\u03b5\u03c2 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b5\u03c2 \u03b1\u03bb\u03bb\u03b7\u03bb\u03bf\u03c5\u03c7\u03af\u03b1\u03c2 \u03b5\u03c0\u03cc\u03bc\u03b5\u03bd\u03b7\u03c2 \u03b3\u03b5\u03bd\u03b9\u03ac\u03c2 \u03b1\u03c0\u03cc \u03b4\u03b5\u03af\u03b3\u03bc\u03b1\u03c4\u03b1 \u03c0\u03bb\u03b1\u03ba\u03bf\u03cd\u03bd\u03c4\u03b1 \u03ba\u03b1\u03b9 \u03b5\u03bc\u03b2\u03c1\u03cd\u03bf\u03c5 \u03b1\u03bc\u03c6\u03b9\u03c3\u03b2\u03ae\u03c4\u03b7\u03c3\u03b1\u03bd \u03c4\u03b7\u03bd \u03c5\u03c0\u03cc\u03b8\u03b5\u03c3\u03b7 \u03bc\u03b9\u03b1\u03c2 \u03c3\u03c4\u03b5\u03af\u03c1\u03b1\u03c2 \u03bc\u03ae\u03c4\u03c1\u03b1\u03c2, \u03ba\u03b1\u03b8\u03ce\u03c2 \u03ad\u03c7\u03bf\u03c5\u03bd \u03b2\u03c1\u03b5\u03b8\u03b5\u03af \u03b8\u03c1\u03b1\u03cd\u03c3\u03bc\u03b1\u03c4\u03b1 \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03b9\u03b1\u03ba\u03bf\u03cd DNA \u03c3\u03c4\u03bf \u03c0\u03b5\u03c1\u03b9\u03b2\u03ac\u03bb\u03bb\u03bf\u03bd \u03c4\u03b7\u03c2 \u03bc\u03ae\u03c4\u03c1\u03b1\u03c2 (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B5\" aria-expanded=\"false\" aria-haspopup=\"true\">Blaser et al., 2021<\/a>\u00a0).\u00a0\u0391\u03c5\u03c4\u03ac \u03c4\u03b1 \u03b5\u03bd\u03b4\u03b9\u03b1\u03c6\u03ad\u03c1\u03bf\u03bd\u03c4\u03b1 \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03ad\u03c3\u03bc\u03b1\u03c4\u03b1 \u03ad\u03c7\u03bf\u03c5\u03bd \u03b5\u03b3\u03b5\u03af\u03c1\u03b5\u03b9 \u03c4\u03bf \u03b5\u03c1\u03ce\u03c4\u03b7\u03bc\u03b1 \u03b5\u03ac\u03bd \u03b7 \u03c0\u03b1\u03c1\u03bf\u03c5\u03c3\u03af\u03b1 \u03bc\u03b9\u03b1\u03c2 \u03b3\u03b7\u03b3\u03b5\u03bd\u03bf\u03cd\u03c2 \u03ba\u03b1\u03b9 \u03b1\u03bd\u03b1\u03c0\u03c4\u03c5\u03c3\u03c3\u03cc\u03bc\u03b5\u03bd\u03b7\u03c2 \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03b9\u03b1\u03ba\u03ae\u03c2 \u03ba\u03bf\u03b9\u03bd\u03cc\u03c4\u03b7\u03c4\u03b1\u03c2 \u03c3\u03c4\u03b7 \u03bc\u03ae\u03c4\u03c1\u03b1 \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03c5\u03c0\u03bf\u03c4\u03b5\u03b8\u03b5\u03af \u03ae \u03b5\u03ac\u03bd \u03c0\u03c1\u03bf\u03ba\u03cd\u03c0\u03c4\u03b5\u03b9 \u03b1\u03c0\u03cc \u03c3\u03c5\u03c3\u03c4\u03b7\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae \u03b4\u03b9\u03b1\u03ba\u03af\u03bd\u03b7\u03c3\u03b7 \u03b2\u03b1\u03ba\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03ce\u03bd \u03bc\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03b9\u03c4\u03ce\u03bd \u03ba\u03b1\u03c4\u03ac \u03c4\u03b7 \u03b4\u03b9\u03ac\u03c1\u03ba\u03b5\u03b9\u03b1 \u03c4\u03b7\u03c2 \u03b5\u03b3\u03ba\u03c5\u03bc\u03bf\u03c3\u03cd\u03bd\u03b7\u03c2 \u03ba\u03b1\u03b9 \u03ba\u03b1\u03c4\u03ac \u03c4\u03bf\u03bd \u03c4\u03bf\u03ba\u03b5\u03c4\u03cc \u03ba\u03b1\u03b9 \u03c0\u03bf\u03b9\u03b5\u03c2 \u03b5\u03af\u03bd\u03b1\u03b9 \u03bf\u03b9 \u03c0\u03b9\u03b8\u03b1\u03bd\u03ad\u03c2 \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03b9\u03ba\u03ad\u03c2 \u03c3\u03c5\u03bd\u03ad\u03c0\u03b5\u03b9\u03b5\u03c2 \u03c3\u03c4\u03bf \u03ad\u03bc\u03b2\u03c1\u03c5\u03bf \u03b1\u03bd\u03ac\u03c0\u03c4\u03c5\u03be\u03b7 (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B5\" aria-expanded=\"false\" aria-haspopup=\"true\">Blaser et al., 2021<\/a>\u00a0).<\/p>\n<p>\u039c\u03ad\u03c7\u03c1\u03b9 \u03c3\u03ae\u03bc\u03b5\u03c1\u03b1, \u03c4\u03b1 \u03b5\u03c0\u03b9\u03c3\u03c4\u03b7\u03bc\u03bf\u03bd\u03b9\u03ba\u03ac \u03c3\u03c4\u03bf\u03b9\u03c7\u03b5\u03af\u03b1 \u03b4\u03b5\u03bd \u03c5\u03c0\u03bf\u03c3\u03c4\u03b7\u03c1\u03af\u03b6\u03bf\u03c5\u03bd \u03c0\u03c1\u03b1\u03b3\u03bc\u03b1\u03c4\u03b9\u03ba\u03ac \u03ad\u03bd\u03b1\u03bd \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03b9\u03b1\u03ba\u03cc \u03b1\u03c0\u03bf\u03b9\u03ba\u03b9\u03c3\u03bc\u03cc in utero, \u03ba\u03b1\u03b9 \u03b7 \u03c3\u03c5\u03bd\u03c4\u03c1\u03b9\u03c0\u03c4\u03b9\u03ba\u03ae \u03c0\u03bb\u03b5\u03b9\u03bf\u03bd\u03cc\u03c4\u03b7\u03c4\u03b1 \u03c4\u03c9\u03bd \u03b1\u03bd\u03b8\u03c1\u03ce\u03c0\u03b9\u03bd\u03c9\u03bd \u03bc\u03b5\u03bb\u03b5\u03c4\u03ce\u03bd \u03b5\u03c0\u03b9\u03b2\u03b5\u03b2\u03b1\u03b9\u03ce\u03bd\u03b5\u03b9 \u03c4\u03b7\u03bd \u03c5\u03c0\u03cc\u03b8\u03b5\u03c3\u03b7 \u03bc\u03b9\u03b1\u03c2 \u03c3\u03c4\u03b5\u03af\u03c1\u03b1\u03c2 \u03bc\u03ae\u03c4\u03c1\u03b1\u03c2, \u03b1\u03bb\u03bb\u03ac \u03b5\u03be\u03b5\u03c4\u03ac\u03b6\u03b5\u03b9 \u03c4\u03b7\u03bd \u03c0\u03b9\u03b8\u03b1\u03bd\u03cc\u03c4\u03b7\u03c4\u03b1 \u03bc\u03b9\u03b1\u03c2 \u03c0\u03b1\u03c1\u03bf\u03b4\u03b9\u03ba\u03ae\u03c2 \u03ad\u03ba\u03b8\u03b5\u03c3\u03b7\u03c2 \u03ba\u03b1\u03c4\u03ac \u03c4\u03b7 \u03b4\u03b9\u03ac\u03c1\u03ba\u03b5\u03b9\u03b1 \u03c4\u03b7\u03c2 \u03ba\u03cd\u03b7\u03c3\u03b7\u03c2 \u03ba\u03b1\u03b9 \u03ba\u03b1\u03c4\u03ac \u03c4\u03b7 \u03c3\u03c4\u03b9\u03b3\u03bc\u03ae \u03c4\u03bf\u03c5 \u03c4\u03bf\u03ba\u03b5\u03c4\u03bf\u03cd (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B5\" aria-expanded=\"false\" aria-haspopup=\"true\">Blaser et al. , 2021<\/a>\u00a0).<\/p>\n<p>\u0395\u03c0\u03b9\u03c0\u03bb\u03ad\u03bf\u03bd, \u03c0\u03c1\u03cc\u03c3\u03c6\u03b1\u03c4\u03b5\u03c2 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b5\u03c2 \u03ad\u03c7\u03bf\u03c5\u03bd \u03b1\u03c0\u03bf\u03b4\u03b5\u03af\u03be\u03b5\u03b9 \u03c5\u03c8\u03b7\u03bb\u03cc\u03c4\u03b5\u03c1\u03b7 \u03c3\u03c4\u03b1\u03b8\u03b5\u03c1\u03cc\u03c4\u03b7\u03c4\u03b1 \u03c4\u03b7\u03c2 \u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03ae\u03c2 \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03b9\u03b1\u03ba\u03ae\u03c2 \u03c3\u03cd\u03bd\u03b8\u03b5\u03c3\u03b7\u03c2, \u03c0\u03bf\u03c5 \u03b1\u03bd\u03c4\u03b9\u03c0\u03c1\u03bf\u03c3\u03c9\u03c0\u03b5\u03cd\u03b5\u03c4\u03b1\u03b9 \u03ba\u03c5\u03c1\u03af\u03c9\u03c2 \u03b1\u03c0\u03cc \u03c4\u03bf\u00a0<em>Lactobacillus<\/em>\u00a0spp.\u00a0\u03bd\u03c9\u03c1\u03af\u03c4\u03b5\u03c1\u03b1 \u03c3\u03c4\u03b7\u03bd \u03b5\u03b3\u03ba\u03c5\u03bc\u03bf\u03c3\u03cd\u03bd\u03b7.\u00a0\u0391\u03c0\u03cc \u03c4\u03b7\u03bd \u03ac\u03bb\u03bb\u03b7 \u03c0\u03bb\u03b5\u03c5\u03c1\u03ac, \u03b7 \u03b5\u03bc\u03c6\u03ac\u03bd\u03b9\u03c3\u03b7 \u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03ce\u03bd \u03bb\u03bf\u03b9\u03bc\u03ce\u03be\u03b5\u03c9\u03bd \u03ba\u03b1\u03c4\u03ac \u03c4\u03b7 \u03b4\u03b9\u03ac\u03c1\u03ba\u03b5\u03b9\u03b1 \u03c4\u03b7\u03c2 \u03b5\u03b3\u03ba\u03c5\u03bc\u03bf\u03c3\u03cd\u03bd\u03b7\u03c2 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03c0\u03c1\u03bf\u03ba\u03b1\u03bb\u03ad\u03c3\u03b5\u03b9 \u03ad\u03bd\u03b1 \u03c0\u03b9\u03bf \u03c0\u03bf\u03b9\u03ba\u03af\u03bb\u03bf \u03ba\u03b1\u03b9 \u03bb\u03b9\u03b3\u03cc\u03c4\u03b5\u03c1\u03bf \u03c3\u03c4\u03b1\u03b8\u03b5\u03c1\u03cc \u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03cc \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03af\u03c9\u03bc\u03b1, \u03b3\u03b9\u03b1 \u03bd\u03b1 \u03b1\u03bb\u03bb\u03ac\u03be\u03b5\u03b9 \u03c4\u03bf \u03c0\u03b5\u03c1\u03b9\u03b2\u03ac\u03bb\u03bb\u03bf\u03bd \u03c4\u03b7\u03c2 \u03bc\u03ae\u03c4\u03c1\u03b1\u03c2.\u00a0\u0391\u03c1\u03ba\u03b5\u03c4\u03ad\u03c2 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b5\u03c2 \u03ad\u03c7\u03bf\u03c5\u03bd \u03b4\u03b5\u03af\u03be\u03b5\u03b9 \u03cc\u03c4\u03b9 \u03c0\u03b5\u03c1\u03af\u03c0\u03bf\u03c5 \u03c4\u03bf 25% \u03c4\u03c9\u03bd \u03c0\u03c1\u03cc\u03c9\u03c1\u03c9\u03bd \u03b2\u03c1\u03b5\u03c6\u03ce\u03bd \u03b3\u03b5\u03bd\u03bd\u03ae\u03b8\u03b7\u03ba\u03b1\u03bd \u03b1\u03c0\u03cc \u03bc\u03b7\u03c4\u03ad\u03c1\u03b5\u03c2 \u03bc\u03b5 \u03b5\u03bd\u03b4\u03bf\u03bc\u03ae\u03c4\u03c1\u03b9\u03b5\u03c2 \u03bb\u03bf\u03b9\u03bc\u03ce\u03be\u03b5\u03b9\u03c2, \u03bf\u03b9 \u03bf\u03c0\u03bf\u03af\u03b5\u03c2 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03c4\u03b5\u03bb\u03b9\u03ba\u03ac \u03bd\u03b1 \u03c3\u03c5\u03bd\u03ad\u03b2\u03b1\u03bb\u03b1\u03bd \u03c3\u03c4\u03b7\u03bd \u03ad\u03bd\u03b1\u03c1\u03be\u03b7 \u03c4\u03bf\u03c5 \u03c0\u03c1\u03cc\u03c9\u03c1\u03bf\u03c5 \u03c4\u03bf\u03ba\u03b5\u03c4\u03bf\u03cd, \u03c5\u03c0\u03bf\u03b4\u03b7\u03bb\u03ce\u03bd\u03bf\u03bd\u03c4\u03b1\u03c2 \u03bc\u03b9\u03b1 \u03c0\u03b9\u03b8\u03b1\u03bd\u03ae \u03ac\u03bc\u03b5\u03c3\u03b7 \u03c3\u03c7\u03ad\u03c3\u03b7 \u03bc\u03b5\u03c4\u03b1\u03be\u03cd \u03c4\u03b7\u03c2 \u03c3\u03cd\u03bd\u03b8\u03b5\u03c3\u03b7\u03c2 \u03c4\u03bf\u03c5 \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03b9\u03ce\u03bc\u03b1\u03c4\u03bf\u03c2 \u03c4\u03bf\u03c5 \u03ba\u03cc\u03bb\u03c0\u03bf\u03c5 \u03ba\u03b1\u03b9 \u03c4\u03c9\u03bd \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03c3\u03bc\u03ac\u03c4\u03c9\u03bd \u03c4\u03b7\u03c2 \u03c0\u03c1\u03ce\u03b9\u03bc\u03b7\u03c2 \u03b6\u03c9\u03ae\u03c2 (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B27\" aria-expanded=\"false\" aria-haspopup=\"true\">Goldenberg et al., 2008<\/a>\u00a0\u00b7\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B1\" aria-expanded=\"false\" aria-haspopup=\"true\">Aagaard et al., 2014<\/a>\u00a0\u00b7\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B64\" aria-expanded=\"false\" aria-haspopup=\"true\">Romero et al., 2014<\/a>\u00a0\u00b7\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B72\" aria-expanded=\"false\" aria-haspopup=\"true\">Tamburini et al., 2016<\/a>\u00a0\u00b7\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B25\" aria-expanded=\"false\" aria-haspopup=\"true\">Freitas et al., 2018<\/a>\u00a0).\u00a0\u0393\u03b9\u03b1 \u03c0\u03b1\u03c1\u03ac\u03b4\u03b5\u03b9\u03b3\u03bc\u03b1, \u03b7 \u03c0\u03b1\u03c1\u03bf\u03c5\u03c3\u03af\u03b1 \u03ba\u03bf\u03b9\u03bd\u03ce\u03bd \u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03ce\u03bd \u03ba\u03b1\u03c4\u03bf\u03af\u03ba\u03c9\u03bd \u03cc\u03c0\u03c9\u03c2\u00a0<em>Burkholderia<\/em>\u00a0\u03ba\u03b1\u03b9\u00a0<em>Lactobacillus iners<\/em>\u00a0\u03ad\u03c7\u03b5\u03b9 \u03b2\u03c1\u03b5\u03b8\u03b5\u03af \u03cc\u03c4\u03b9 \u03c3\u03c7\u03b5\u03c4\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03c0\u03c1\u03cc\u03c9\u03c1\u03bf \u03c4\u03bf\u03ba\u03b5\u03c4\u03cc (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B1\" aria-expanded=\"false\" aria-haspopup=\"true\">Aagaard et al., 2014<\/a>\u00a0), \u03b5\u03bd\u03ce \u03b7 \u03c0\u03b1\u03c1\u03bf\u03c5\u03c3\u03af\u03b1 \u03c4\u03c9\u03bd\u00a0<em>A. vaginae<\/em>\u00a0\u03ba\u03b1\u03b9\u00a0<em>Leptotrichia<\/em>\u00a0spp.\u00a0\u03c3\u03c5\u03bd\u03b4\u03ad\u03b5\u03c4\u03b1\u03b9 \u03c3\u03c5\u03bd\u03ae\u03b8\u03c9\u03c2 \u03bc\u03b5 \u03b4\u03c5\u03c3\u03b2\u03b9\u03bf\u03c4\u03b9\u03ba\u03ae \u03ba\u03b1\u03c4\u03ac\u03c3\u03c4\u03b1\u03c3\u03b7 (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B65\" aria-expanded=\"false\" aria-haspopup=\"true\">Romero et al., 2014<\/a>\u00a0).\u00a0\u03a9\u03c3\u03c4\u03cc\u03c3\u03bf, \u03c4\u03b1 \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03ad\u03c3\u03bc\u03b1\u03c4\u03b1 \u03b1\u03c5\u03c4\u03ac \u03c7\u03c1\u03ae\u03b6\u03bf\u03c5\u03bd \u03c0\u03b5\u03c1\u03b1\u03b9\u03c4\u03ad\u03c1\u03c9 \u03ba\u03b1\u03b9 \u03b1\u03ba\u03c1\u03b9\u03b2\u03ad\u03c3\u03c4\u03b5\u03c1\u03c9\u03bd \u03b5\u03c1\u03b5\u03c5\u03bd\u03ce\u03bd, \u03bb\u03cc\u03b3\u03c9 \u03c4\u03c9\u03bd \u03bc\u03b5\u03b8\u03bf\u03b4\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ce\u03bd \u03ba\u03b1\u03b9 \u03c4\u03b5\u03c7\u03bd\u03b9\u03ba\u03ce\u03bd \u03c0\u03c1\u03bf\u03b2\u03bb\u03b7\u03bc\u03b1\u03c4\u03b9\u03c3\u03bc\u03ce\u03bd \u03c4\u03c9\u03bd \u03b5\u03c1\u03b5\u03c5\u03bd\u03b7\u03c4\u03b9\u03ba\u03ce\u03bd \u03b5\u03c1\u03b3\u03b1\u03c3\u03b9\u03ce\u03bd \u03c0\u03bf\u03c5 \u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c5\u03c0\u03cc\u03c8\u03b7.<\/p>\n<p>\u0395\u03bd\u03ce \u03b4\u03b9\u03ac\u03c6\u03bf\u03c1\u03bf\u03b9 \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b5\u03c2, \u03c3\u03c5\u03bc\u03c0\u03b5\u03c1\u03b9\u03bb\u03b1\u03bc\u03b2\u03b1\u03bd\u03bf\u03bc\u03ad\u03bd\u03bf\u03c5 \u03c4\u03bf\u03c5 \u03c4\u03c1\u03cc\u03c0\u03bf\u03c5 \u03c4\u03bf\u03ba\u03b5\u03c4\u03bf\u03cd, \u03c4\u03c9\u03bd \u03c0\u03b5\u03c1\u03b9\u03b2\u03b1\u03bb\u03bb\u03bf\u03bd\u03c4\u03b9\u03ba\u03ce\u03bd \u03b5\u03ba\u03b8\u03ad\u03c3\u03b5\u03c9\u03bd, \u03c4\u03c9\u03bd \u03b1\u03bd\u03c4\u03b9\u03b2\u03b9\u03bf\u03c4\u03b9\u03ba\u03ce\u03bd, \u03c4\u03bf\u03c5 \u03b8\u03b7\u03bb\u03b1\u03c3\u03bc\u03bf\u03cd, \u03c4\u03b7\u03c2 \u03c0\u03c1\u03cc\u03c3\u03bb\u03b7\u03c8\u03b7\u03c2 \u03c0\u03c1\u03bf\u03b2\u03b9\u03bf\u03c4\u03b9\u03ba\u03ce\u03bd \u03ba\u03b1\u03b9 \u03c0\u03c1\u03b5\u03b2\u03b9\u03bf\u03c4\u03b9\u03ba\u03ce\u03bd \u03ba\u03b1\u03b9 \u03b3\u03b5\u03bd\u03b5\u03c4\u03b9\u03ba\u03ad\u03c2 \u03c0\u03c4\u03c5\u03c7\u03ad\u03c2, \u03ad\u03c7\u03bf\u03c5\u03bd \u03c3\u03c5\u03c3\u03c7\u03b5\u03c4\u03b9\u03c3\u03c4\u03b5\u03af \u03bc\u03b5 \u03b1\u03bb\u03bb\u03b1\u03b3\u03ad\u03c2 \u03c3\u03c4\u03bf \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03af\u03c9\u03bc\u03b1 \u03c4\u03bf\u03c5 \u03b5\u03bd\u03c4\u03ad\u03c1\u03bf\u03c5 \u03c3\u03c4\u03b7\u03bd \u03c0\u03c1\u03ce\u03b9\u03bc\u03b7 \u03b6\u03c9\u03ae, \u03c0\u03bf\u03bb\u03cd \u03bb\u03af\u03b3\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b3\u03bd\u03c9\u03c3\u03c4\u03ac \u03b3\u03b9\u03b1 \u03c4\u03bf\u03bd \u03c1\u03cc\u03bb\u03bf \u03b1\u03c5\u03c4\u03ce\u03bd \u03c4\u03c9\u03bd \u03ba\u03b1\u03b8\u03bf\u03c1\u03b9\u03c3\u03c4\u03b9\u03ba\u03ce\u03bd \u03c0\u03b1\u03c1\u03b1\u03b3\u03cc\u03bd\u03c4\u03c9\u03bd \u03c3\u03c4\u03bf \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03b9\u03b1\u03ba\u03cc \u03c4\u03bf\u03c5 \u03ba\u03cc\u03bb\u03c0\u03bf\u03c5. \u03c3\u03cd\u03bd\u03b8\u03b5\u03c3\u03b7 (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B72\" aria-expanded=\"false\" aria-haspopup=\"true\">Tamburini et al., 2016<\/a>\u00a0).<\/p>\n<p>\u03a3\u03c4\u03b1 \u03bd\u03b5\u03bf\u03b3\u03ad\u03bd\u03bd\u03b7\u03c4\u03b1 \u03c4\u03bf \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03af\u03c9\u03bc\u03b1 \u03c4\u03bf\u03c5 \u03ba\u03cc\u03bb\u03c0\u03bf\u03c5 \u03b5\u03c0\u03b7\u03c1\u03b5\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03ba\u03c5\u03c1\u03af\u03c9\u03c2 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03c0\u03b1\u03c1\u03bf\u03c5\u03c3\u03af\u03b1 \u03b4\u03b9\u03b1\u03c0\u03bb\u03b1\u03ba\u03bf\u03c5\u03bd\u03c4\u03b9\u03b1\u03ba\u03ce\u03bd \u03bf\u03b9\u03c3\u03c4\u03c1\u03bf\u03b3\u03cc\u03bd\u03c9\u03bd \u03b3\u03b9\u03b1 \u03c0\u03b1\u03c1\u03bf\u03c7\u03ae \u03b3\u03bb\u03c5\u03ba\u03bf\u03b3\u03cc\u03bd\u03bf\u03c5, \u03c4\u03bf \u03bf\u03c0\u03bf\u03af\u03bf \u03bc\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03ba\u03b1\u03bd\u03bf\u03bd\u03b9\u03ba\u03ac \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03b1\u03bd\u03b8\u03c1\u03ce\u03c0\u03b9\u03bd\u03b7 \u03b1-\u03b1\u03bc\u03c5\u03bb\u03ac\u03c3\u03b7 \u03c3\u03b5 \u03bc\u03b1\u03bb\u03c4\u03cc\u03b6\u03b7 \u03ba\u03b1\u03b9 \u03bc\u03b1\u03bb\u03c4\u03bf\u03c4\u03c1\u03b9\u03cc\u03b6\u03b7 \u03c0\u03bf\u03c5 \u03c7\u03c1\u03b7\u03c3\u03b9\u03bc\u03bf\u03c0\u03bf\u03b9\u03b5\u03af\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03bf LAB \u03c9\u03c2 \u03bc\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03b9\u03ba\u03cc \u03c5\u03c0\u03cc\u03c3\u03c4\u03c1\u03c9\u03bc\u03b1 \u03b3\u03b9\u03b1 \u03c4\u03b7\u03bd \u03c0\u03b1\u03c1\u03b1\u03b3\u03c9\u03b3\u03ae \u03b3\u03b1\u03bb\u03b1\u03ba\u03c4\u03b9\u03ba\u03bf\u03cd \u03bf\u03be\u03ad\u03bf\u03c2 (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B20\" aria-expanded=\"false\" aria-haspopup=\"true\">Dur\u00e1n et al., 2020<\/a>\u00a0).\u00a0\u0395\u03c0\u03bf\u03bc\u03ad\u03bd\u03c9\u03c2, \u03b7 \u03be\u03b1\u03c6\u03bd\u03b9\u03ba\u03ae \u03b4\u03b9\u03b1\u03ba\u03bf\u03c0\u03ae \u03c4\u03c9\u03bd \u03b4\u03b9\u03b1\u03c0\u03bb\u03b1\u03ba\u03bf\u03c5\u03bd\u03c4\u03b9\u03b1\u03ba\u03ce\u03bd \u03bf\u03b9\u03c3\u03c4\u03c1\u03bf\u03b3\u03cc\u03bd\u03c9\u03bd \u03ad\u03c7\u03b5\u03b9 \u03b1\u03bd\u03b1\u03c6\u03b5\u03c1\u03b8\u03b5\u03af \u03cc\u03c4\u03b9 \u03bc\u03b5\u03b9\u03ce\u03bd\u03b5\u03b9 \u03c4\u03b7\u03bd \u03c0\u03b5\u03c1\u03b9\u03b5\u03ba\u03c4\u03b9\u03ba\u03cc\u03c4\u03b7\u03c4\u03b1 \u03c3\u03b5 \u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03cc \u03b3\u03bb\u03c5\u03ba\u03bf\u03b3\u03cc\u03bd\u03bf, \u03ad\u03c4\u03c3\u03b9 \u03ce\u03c3\u03c4\u03b5 \u03c4\u03bf \u03c0\u03c1\u03bf\u03ba\u03cd\u03c0\u03c4\u03bf\u03bd \u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03cc pH \u03bd\u03b1 \u03b5\u03be\u03bf\u03c5\u03b4\u03b5\u03c4\u03b5\u03c1\u03ce\u03bd\u03b5\u03c4\u03b1\u03b9 \u03ae \u03bd\u03b1 \u03b1\u03bb\u03ba\u03b1\u03bb\u03bf\u03c0\u03bf\u03b9\u03b5\u03af\u03c4\u03b1\u03b9 (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B45\" aria-expanded=\"false\" aria-haspopup=\"true\">Miller et al., 2016<\/a>\u00a0).<\/p>\n<p>\u03a3\u03c4\u03b1 \u03c0\u03b1\u03b9\u03b4\u03b9\u03ba\u03ac \u03ba\u03b1\u03b9 \u03c0\u03c1\u03bf\u03b5\u03c6\u03b7\u03b2\u03b9\u03ba\u03ac \u03c3\u03c4\u03ac\u03b4\u03b9\u03b1, \u03c4\u03bf \u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03cc pH \u03c0\u03b1\u03c1\u03b1\u03bc\u03ad\u03bd\u03b5\u03b9 \u03bf\u03c5\u03b4\u03ad\u03c4\u03b5\u03c1\u03bf \u03ae \u03b1\u03bb\u03ba\u03b1\u03bb\u03b9\u03ba\u03cc \u03ba\u03b1\u03b9 \u03b5\u03c0\u03b7\u03c1\u03b5\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b7 \u03c3\u03c5\u03bd\u03b5\u03c7\u03ae \u03c0\u03b1\u03c1\u03bf\u03c5\u03c3\u03af\u03b1 \u03b1\u03b5\u03c1\u03cc\u03b2\u03b9\u03c9\u03bd, \u03b1\u03c5\u03c3\u03c4\u03b7\u03c1\u03ac \u03b1\u03bd\u03b1\u03b5\u03c1\u03cc\u03b2\u03b9\u03c9\u03bd \u03ba\u03b1\u03b9 \u03b5\u03bd\u03c4\u03b5\u03c1\u03b9\u03ba\u03ce\u03bd \u03b5\u03b9\u03b4\u03ce\u03bd \u03b2\u03b1\u03ba\u03c4\u03b7\u03c1\u03af\u03c9\u03bd (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B18\" aria-expanded=\"false\" aria-haspopup=\"true\">Donders et al., 2000<\/a>\u00a0;\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B42\" aria-expanded=\"false\" aria-haspopup=\"true\">Marrazzo, 2006<\/a>\u00a0;\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B64\" aria-expanded=\"false\" aria-haspopup=\"true\">Romero et al., 2014<\/a>\u00a0) \u03b5\u03bd\u03ce \u03c4\u03b1 LAB \u03b2\u03c1\u03af\u03c3\u03ba\u03bf\u03bd\u03c4\u03b1\u03b9 \u03bc\u03cc\u03bd\u03bf \u03c3\u03c0\u03bf\u03c1\u03b1\u03b4\u03b9\u03ba\u03ac (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B29\" aria-expanded=\"false\" aria-haspopup=\"true\">Hammerschlag et al., 1978a<\/a>\u00a0;\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B30\" aria-expanded=\"false\" aria-haspopup=\"true\">Hammerschlag et al., 1978b<\/a>\u00a0;\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B73\" aria-expanded=\"false\" aria-haspopup=\"true\">Thoma et al., 2011<\/a>\u00a0).\u00a0\u0391\u03c1\u03b3\u03cc\u03c4\u03b5\u03c1\u03b1, \u03b7 \u03ad\u03bd\u03b1\u03c1\u03be\u03b7 \u03c4\u03b7\u03c2 \u03b5\u03c6\u03b7\u03b2\u03b5\u03af\u03b1\u03c2 \u03c0\u03c1\u03bf\u03ba\u03b1\u03bb\u03b5\u03af \u03b1\u03cd\u03be\u03b7\u03c3\u03b7 \u03c4\u03c9\u03bd \u03b5\u03c0\u03b9\u03c0\u03ad\u03b4\u03c9\u03bd \u03bf\u03b9\u03c3\u03c4\u03c1\u03bf\u03b3\u03cc\u03bd\u03c9\u03bd \u03ba\u03b1\u03b9 \u03c0\u03c1\u03bf\u03b3\u03b5\u03c3\u03c4\u03b5\u03c1\u03cc\u03bd\u03b7\u03c2 \u03bc\u03b5 \u03c4\u03b7\u03bd \u03b1\u03bd\u03b1\u03bc\u03cc\u03c1\u03c6\u03c9\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03bf\u03cd \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03b9\u03ce\u03bc\u03b1\u03c4\u03bf\u03c2, \u03b5\u03c5\u03bd\u03bf\u03ce\u03bd\u03c4\u03b1\u03c2 \u03ad\u03c4\u03c3\u03b9 \u03c4\u03bf\u03bd \u03b1\u03c0\u03bf\u03b9\u03ba\u03b9\u03c3\u03bc\u03cc \u03c4\u03c9\u03bd LAB \u03c3\u03b5 \u03cc\u03bb\u03b7 \u03c4\u03b7\u03bd \u03b1\u03bd\u03b1\u03c0\u03b1\u03c1\u03b1\u03b3\u03c9\u03b3\u03b9\u03ba\u03ae \u03b7\u03bb\u03b9\u03ba\u03af\u03b1 \u03c4\u03c9\u03bd \u03b3\u03c5\u03bd\u03b1\u03b9\u03ba\u03ce\u03bd.\u00a0\u039c\u03b9\u03b1 \u03bf\u03bb\u03bf\u03ba\u03bb\u03b7\u03c1\u03c9\u03bc\u03ad\u03bd\u03b7 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b7 \u03b1\u03c0\u03cc \u03c4\u03bf\u03c5\u03c2\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B21\" aria-expanded=\"false\" aria-haspopup=\"true\">Eschenbach et al.\u00a0(2000)<\/a>\u00a0\u03ad\u03c7\u03b5\u03b9 \u03b4\u03b5\u03af\u03be\u03b5\u03b9 \u03cc\u03c4\u03b9 \u03c4\u03bf \u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03cc \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03af\u03c9\u03bc\u03b1 \u03b1\u03bb\u03bb\u03ac\u03b6\u03b5\u03b9 \u03b5\u03c0\u03af\u03c3\u03b7\u03c2 \u03bc\u03b5 \u03c4\u03b9\u03c2 \u03bf\u03c1\u03bc\u03bf\u03bd\u03b9\u03ba\u03ad\u03c2 \u03b4\u03b9\u03b1\u03ba\u03c5\u03bc\u03ac\u03bd\u03c3\u03b5\u03b9\u03c2 \u03c0\u03bf\u03c5 \u03c3\u03c5\u03bc\u03b2\u03b1\u03af\u03bd\u03bf\u03c5\u03bd \u03c3\u03c5\u03bd\u03ae\u03b8\u03c9\u03c2 \u03ba\u03b1\u03c4\u03ac \u03c4\u03b7 \u03b4\u03b9\u03ac\u03c1\u03ba\u03b5\u03b9\u03b1 \u03c4\u03b7\u03c2 \u03b5\u03bc\u03bc\u03ae\u03bd\u03bf\u03c5 \u03c1\u03cd\u03c3\u03b5\u03c9\u03c2.\u00a0\u0399\u03b4\u03b9\u03b1\u03af\u03c4\u03b5\u03c1\u03b1, \u03c3\u03b5 \u03c5\u03b3\u03b9\u03b5\u03af\u03c2 \u03b3\u03c5\u03bd\u03b1\u03af\u03ba\u03b5\u03c2 \u03c7\u03c9\u03c1\u03af\u03c2 \u03b2\u03b1\u03ba\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03ae \u03ba\u03bf\u03bb\u03c0\u03af\u03c4\u03b9\u03b4\u03b1, \u03b2\u03c1\u03ad\u03b8\u03b7\u03ba\u03b5 \u03cc\u03c4\u03b9 \u03bf\u00a0<em>Lactobacillus<\/em>\u00a0spp.\u00a0\u03b1\u03c5\u03be\u03ae\u03b8\u03b7\u03ba\u03b5 \u03ba\u03c5\u03c1\u03af\u03c9\u03c2 \u03b5\u03bd\u03ce\u00a0<em>\u03c4\u03bf Prevotella<\/em>\u00a0sp.\u00a0\u03bc\u03b5\u03b9\u03ce\u03b8\u03b7\u03ba\u03b5 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03b7\u03bc\u03ad\u03c1\u03b1 1 \u03ad\u03c9\u03c2 \u03c4\u03b7\u03bd 24\u03b7 \u03b7\u03bc\u03ad\u03c1\u03b1 \u03c4\u03bf\u03c5 \u03b5\u03bc\u03bc\u03b7\u03bd\u03bf\u03c1\u03c1\u03bf\u03ca\u03ba\u03bf\u03cd \u03ba\u03cd\u03ba\u03bb\u03bf\u03c5 (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B21\" aria-expanded=\"false\" aria-haspopup=\"true\">Eschenbach et al., 2000<\/a>\u00a0).<\/p>\n<p class=\"p p-last\">\u03a4\u03bf \u03b5\u03ac\u03bd \u03c4\u03bf \u03c0\u03b5\u03c1\u03b9\u03b2\u03ac\u03bb\u03bb\u03bf\u03bd \u03c4\u03bf\u03c5 \u03bc\u03b7\u03c4\u03c1\u03b9\u03ba\u03bf\u03cd \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03b9\u03ce\u03bc\u03b1\u03c4\u03bf\u03c2 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b5\u03c0\u03b7\u03c1\u03b5\u03ac\u03c3\u03b5\u03b9 \u03c4\u03b7\u03bd \u03ba\u03b1\u03c4\u03ac\u03c3\u03c4\u03b1\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03c5\u03b3\u03b5\u03af\u03b1\u03c2 \u03bc\u03b5\u03c4\u03ac \u03c4\u03b7 \u03b3\u03ad\u03bd\u03bd\u03b7\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03ba\u03b1\u03c4\u03ac \u03c4\u03b7\u03bd \u03c0\u03b1\u03b9\u03b4\u03b9\u03ba\u03ae \u03b7\u03bb\u03b9\u03ba\u03af\u03b1 \u03b4\u03b5\u03bd \u03ad\u03c7\u03b5\u03b9 \u03b1\u03ba\u03cc\u03bc\u03b7 \u03b1\u03c0\u03bf\u03c3\u03b1\u03c6\u03b7\u03bd\u03b9\u03c3\u03c4\u03b5\u03af \u03c0\u03bb\u03ae\u03c1\u03c9\u03c2.\u00a0\u0397 \u03c3\u03b7\u03bc\u03b1\u03c3\u03af\u03b1 \u03c4\u03b7\u03c2 \u03b1\u03bd\u03c4\u03b1\u03bb\u03bb\u03b1\u03b3\u03ae\u03c2 \u03b1\u03c0\u03b1\u03c1\u03b1\u03af\u03c4\u03b7\u03c4\u03c9\u03bd \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03af\u03c9\u03bd \u03bc\u03b5\u03c4\u03b1\u03be\u03cd \u03bc\u03b7\u03c4\u03ad\u03c1\u03b1\u03c2 \u03ba\u03b1\u03b9 \u03bd\u03b5\u03bf\u03b3\u03bd\u03bf\u03cd \u03b3\u03b9\u03b1 \u03c4\u03b7\u03bd \u03c5\u03c0\u03bf\u03c3\u03c4\u03ae\u03c1\u03b9\u03be\u03b7 \u03c4\u03c9\u03bd \u03c0\u03c1\u03ce\u03b9\u03bc\u03c9\u03bd \u03c3\u03c4\u03b1\u03b4\u03af\u03c9\u03bd \u03b6\u03c9\u03ae\u03c2 \u03b1\u03bd\u03bf\u03af\u03b3\u03b5\u03b9 \u03c3\u03c4\u03b7 \u03c7\u03c1\u03ae\u03c3\u03b7 \u03c3\u03c5\u03bc\u03c0\u03bb\u03b7\u03c1\u03c9\u03bc\u03ac\u03c4\u03c9\u03bd \u03c0\u03c1\u03bf\u03b2\u03b9\u03bf\u03c4\u03b9\u03ba\u03ce\u03bd \u03c3\u03c4\u03b1 \u03bd\u03b5\u03bf\u03b3\u03bd\u03ac (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B7\" aria-expanded=\"false\" aria-haspopup=\"true\">Braegger et al., 2011<\/a>\u00a0).\u00a0\u0391\u03c0\u03cc \u03b1\u03c5\u03c4\u03ae \u03c4\u03b7\u03bd \u03ac\u03c0\u03bf\u03c8\u03b7, \u03c4\u03b1 \u03c3\u03c5\u03bc\u03c0\u03bb\u03b7\u03c1\u03ce\u03bc\u03b1\u03c4\u03b1 \u03b5\u03bc\u03c0\u03bb\u03bf\u03c5\u03c4\u03b9\u03c3\u03bc\u03ad\u03bd\u03b1 \u03bc\u03b5\u00a0<em>Lactobacillus<\/em>\u00a0\u03ba\u03b1\u03b9\u00a0<em>Bifidobacterium<\/em>\u00a0\u03ad\u03c7\u03bf\u03c5\u03bd \u03b1\u03c0\u03bf\u03b4\u03b5\u03b9\u03c7\u03b8\u03b5\u03af \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03c3\u03bc\u03b1\u03c4\u03b9\u03ba\u03ac \u03c3\u03c4\u03b7 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u03c4\u03b7\u03c2 \u03b1\u03c4\u03bf\u03c0\u03b9\u03ba\u03ae\u03c2 \u03b4\u03b5\u03c1\u03bc\u03b1\u03c4\u03af\u03c4\u03b9\u03b4\u03b1\u03c2 (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B53\" aria-expanded=\"false\" aria-haspopup=\"true\">Panduru et al., 2015<\/a>\u00a0) \u03ba\u03b1\u03b9 \u03c4\u03b7\u03c2 \u03b2\u03c1\u03b5\u03c6\u03b9\u03ba\u03ae\u03c2 \u03ba\u03bf\u03bb\u03af\u03c4\u03b9\u03b4\u03b1\u03c2 (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B67\" aria-expanded=\"false\" aria-haspopup=\"true\">Savino et al., 2010<\/a>\u00a0), \u03c0\u03b9\u03b8\u03b1\u03bd\u03ce\u03c2 \u03bb\u03cc\u03b3\u03c9 \u03c4\u03b7\u03c2 \u03b9\u03ba\u03b1\u03bd\u03cc\u03c4\u03b7\u03c4\u03ac\u03c2 \u03c4\u03bf\u03c5\u03c2 \u03bd\u03b1 \u03b1\u03bd\u03b1\u03b4\u03b9\u03b1\u03bc\u03bf\u03c1\u03c6\u03ce\u03bd\u03bf\u03c5\u03bd \u03c4\u03bf \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03af\u03c9\u03bc\u03b1 \u03c4\u03bf\u03c5 \u03b5\u03bd\u03c4\u03ad\u03c1\u03bf\u03c5 ;\u00a0\u03a9\u03c3\u03c4\u03cc\u03c3\u03bf, \u03b4\u03b5\u03bd \u03ad\u03c7\u03bf\u03c5\u03bd \u03b1\u03bd\u03b1\u03c6\u03b5\u03c1\u03b8\u03b5\u03af \u03c0\u03bf\u03c4\u03ad \u03c3\u03c4\u03bf\u03b9\u03c7\u03b5\u03af\u03b1 \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03b9\u03ba\u03ce\u03bd \u03b5\u03c0\u03b9\u03b4\u03c1\u03ac\u03c3\u03b5\u03c9\u03bd \u03c3\u03c4\u03bf \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03af\u03c9\u03bc\u03b1 \u03c4\u03bf\u03c5 \u03ba\u03cc\u03bb\u03c0\u03bf\u03c5.\u00a0\u0388\u03c4\u03c3\u03b9, \u03bc\u03b5 \u03b2\u03ac\u03c3\u03b7 \u03b1\u03c5\u03c4\u03ad\u03c2 \u03c4\u03b9\u03c2 \u03c0\u03c1\u03bf\u03ba\u03b1\u03c4\u03b1\u03c1\u03ba\u03c4\u03b9\u03ba\u03ad\u03c2 \u03c0\u03b1\u03c1\u03b1\u03c4\u03b7\u03c1\u03ae\u03c3\u03b5\u03b9\u03c2, \u03b8\u03b1 \u03ae\u03c4\u03b1\u03bd \u03c0\u03bf\u03bb\u03cd \u03b5\u03bd\u03b4\u03b9\u03b1\u03c6\u03ad\u03c1\u03bf\u03bd \u03bd\u03b1 \u03ba\u03b1\u03c4\u03b1\u03bd\u03bf\u03ae\u03c3\u03bf\u03c5\u03bc\u03b5 \u03b5\u03ac\u03bd \u03ba\u03b1\u03b9 \u03c0\u03ce\u03c2 \u03c4\u03b1 \u03c0\u03c1\u03bf\u03b2\u03b9\u03bf\u03c4\u03b9\u03ba\u03ac \u03bc\u03c0\u03bf\u03c1\u03bf\u03cd\u03bd \u03bd\u03b1 \u03b5\u03c0\u03b7\u03c1\u03b5\u03ac\u03c3\u03bf\u03c5\u03bd \u03c4\u03bf \u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03cc \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03af\u03c9\u03bc\u03b1 (\u03c0\u03ad\u03c1\u03b1 \u03b1\u03c0\u03cc \u03c4\u03bf \u03b5\u03bd\u03c4\u03b5\u03c1\u03b9\u03ba\u03cc \u03c3\u03cd\u03c3\u03c4\u03b7\u03bc\u03b1) \u03ba\u03b1\u03b9 \u03b5\u03c0\u03af\u03c3\u03b7\u03c2 \u03bd\u03b1 \u03c0\u03c1\u03bf\u03c3\u03c4\u03b1\u03c4\u03b5\u03cd\u03c3\u03bf\u03c5\u03bd \u03b1\u03c0\u03cc \u03b4\u03b9\u03ac\u03c6\u03bf\u03c1\u03b5\u03c2 \u03b1\u03c3\u03b8\u03ad\u03bd\u03b5\u03b9\u03b5\u03c2 \u03c4\u03bf\u03c5 \u03bd\u03b5\u03bf\u03b3\u03bd\u03bf\u03cd.<\/p>\n<h2 id=\"s3title\" class=\"head no_bottom_margin ui-helper-clearfix\"><span style=\"color: #ff0000;\">\u0393\u03c5\u03bd\u03b1\u03af\u03ba\u03b5\u03c2 \u0391\u03bd\u03b1\u03c0\u03b1\u03c1\u03b1\u03b3\u03c9\u03b3\u03b9\u03ba\u03ae\u03c2 \u0397\u03bb\u03b9\u03ba\u03af\u03b1\u03c2<\/span><\/h2>\n<p class=\"p p-first\">\u03a3\u03b5 \u03b3\u03c5\u03bd\u03b1\u03af\u03ba\u03b5\u03c2 \u03b1\u03bd\u03b1\u03c0\u03b1\u03c1\u03b1\u03b3\u03c9\u03b3\u03b9\u03ba\u03ae\u03c2 \u03b7\u03bb\u03b9\u03ba\u03af\u03b1\u03c2, \u03c4\u03bf \u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03cc \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03af\u03c9\u03bc\u03b1 \u03c6\u03b9\u03bb\u03bf\u03be\u03b5\u03bd\u03b5\u03af \u03bc\u03b9\u03b1 \u03c3\u03b5\u03b9\u03c1\u03ac \u03b1\u03c0\u03cc \u03b2\u03b1\u03ba\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03ad\u03c2 \u03ba\u03bf\u03b9\u03bd\u03cc\u03c4\u03b7\u03c4\u03b5\u03c2, \u03c3\u03c5\u03bc\u03c0\u03b5\u03c1\u03b9\u03bb\u03b1\u03bc\u03b2\u03b1\u03bd\u03bf\u03bc\u03ad\u03bd\u03c9\u03bd \u03c4\u03c9\u03bd \u03c0\u03b5\u03c1\u03b9\u03c3\u03c3\u03cc\u03c4\u03b5\u03c1\u03c9\u03bd \u03b5\u03b9\u03b4\u03ce\u03bd \u03c4\u03bf\u03c5 \u03b3\u03ad\u03bd\u03bf\u03c5\u03c2\u00a0<em>Lactobacillus<\/em>\u00a0(\u00a0<em>L. crispatus<\/em>\u00a0,\u00a0<em>L. gasseri<\/em>\u00a0,\u00a0<em>L. jensenii<\/em>\u00a0\u03ba\u03b1\u03b9\u00a0<em>L. iners<\/em>\u00a0) (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B76\" aria-expanded=\"false\" aria-haspopup=\"true\">Vasquez et al., 2002<\/a>\u00a0;\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B24\" aria-expanded=\"false\" aria-haspopup=\"true\">Fredricks et al., 2005<\/a>\u00a0), \u03b1\u03bd\u03b1\u03b5\u03c1\u03cc\u03b2\u03b9\u03b1 \u03b2\u03b1\u03ba\u03c4\u03ae\u03c1\u03b9\u03b1 \u03ba\u03b1\u03b9 \u03bc\u03b5\u03c4\u03b1\u03b2\u03bb\u03b7\u03c4\u03ad\u03c2 \u03c0\u03bf\u03c3\u03cc\u03c4\u03b7\u03c4\u03b5\u03c2 \u03ac\u03bb\u03bb\u03c9\u03bd \u03bb\u03b9\u03b3\u03cc\u03c4\u03b5\u03c1\u03bf \u03ba\u03bf\u03b9\u03bd\u03ce\u03bd \u03b2\u03b1\u03ba\u03c4\u03b7\u03c1\u03af\u03c9\u03bd (\u03c0.\u03c7.\u00a0<em>Atopobium<\/em>\u00a0,\u00a0<em>Prevotella<\/em>\u00a0,\u00a0<em>Parvimonas<\/em>\u00a0,\u00a0<em>Sneathia<\/em>\u00a0,\u00a0<em>Gardnerella<\/em>\u00a0,\u00a0<em>Mobiluncus<\/em>\u00a0\u03ba\u03b1\u03b9\u00a0<em>Peptoniphilus<\/em>\u00a0), \u03c4\u03b1 \u03bf\u03c0\u03bf\u03af\u03b1 \u03c0\u03b1\u03c1\u03b1\u03c4\u03b7\u03c1\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9 \u03c3\u03c5\u03c7\u03bd\u03cc\u03c4\u03b5\u03c1\u03b1 \u03c3\u03c4\u03b7 \u03b2\u03b1\u03ba\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03ae \u03ba\u03bf\u03bb\u03c0\u03af\u03c4\u03b9\u03b4\u03b1 (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B14\" aria-expanded=\"false\" aria-haspopup=\"true\">Coolen et al., 2<\/a>\u00a0;\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B43\" aria-expanded=\"false\" aria-haspopup=\"true\">Marrazzo, 2011<\/a>\u00a0).<\/p>\n<p>\u03a3\u03b5 \u03cc\u03bb\u03b7 \u03c4\u03b7\u03bd \u03b1\u03bd\u03b1\u03c0\u03b1\u03c1\u03b1\u03b3\u03c9\u03b3\u03b9\u03ba\u03ae \u03b7\u03bb\u03b9\u03ba\u03af\u03b1, \u03c4\u03bf \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03af\u03c9\u03bc\u03b1 \u03c4\u03bf\u03c5 \u03ba\u03cc\u03bb\u03c0\u03bf\u03c5 \u03b5\u03ba\u03c4\u03af\u03b8\u03b5\u03c4\u03b1\u03b9 \u03c3\u03b5 \u03bf\u03b9\u03c3\u03c4\u03c1\u03bf\u03b3\u03cc\u03bd\u03b1 \u03ba\u03b1\u03b9 \u03c0\u03c1\u03bf\u03b3\u03b5\u03c3\u03c4\u03af\u03bd\u03b7 \u03ba\u03b1\u03b9 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03c3\u03c5\u03bc\u03b2\u03bf\u03cd\u03bd \u03bf\u03c1\u03b9\u03c3\u03bc\u03ad\u03bd\u03b5\u03c2 \u03ba\u03c1\u03af\u03c3\u03b9\u03bc\u03b5\u03c2 \u03b1\u03bb\u03bb\u03b1\u03b3\u03ad\u03c2, \u03cc\u03c0\u03c9\u03c2 \u03bc\u03b5\u03af\u03c9\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03c4\u03bf\u03c0\u03b9\u03ba\u03bf\u03cd pH (&lt;4,5) \u03bb\u03cc\u03b3\u03c9 \u03bc\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03b9\u03c3\u03bc\u03bf\u03cd \u03c4\u03bf\u03c5 \u03b3\u03bb\u03c5\u03ba\u03bf\u03b3\u03cc\u03bd\u03bf\u03c5, \u03bf \u03bf\u03c0\u03bf\u03af\u03bf\u03c2 \u03bc\u03b5 \u03c4\u03b7 \u03c3\u03b5\u03b9\u03c1\u03ac \u03c4\u03bf\u03c5 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03c0\u03b5\u03c1\u03b9\u03bf\u03c1\u03af\u03c3\u03b5\u03b9 \u03c4\u03b7\u03bd \u03b1\u03bd\u03ac\u03c0\u03c4\u03c5\u03be\u03b7 \u03c0\u03bf\u03bb\u03bb\u03ce\u03bd \u03c0\u03b1\u03b8\u03bf\u03b3\u03cc\u03bd\u03c9\u03bd \u03ba\u03b1\u03b9 \u03b1\u03ba\u03cc\u03bc\u03b7 \u03ba\u03b1\u03b9 \u03bd\u03b1 \u03c0\u03c1\u03bf\u03ba\u03b1\u03bb\u03ad\u03c3\u03b5\u03b9 \u03b4\u03bf\u03bc\u03b9\u03ba\u03ad\u03c2 \u03c4\u03c1\u03bf\u03c0\u03bf\u03c0\u03bf\u03b9\u03ae\u03c3\u03b5\u03b9\u03c2 \u03c4\u03bf\u03c5 \u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03bf\u03cd \u03b5\u03c0\u03b9\u03b8\u03b7\u03bb\u03af\u03bf\u03c5 (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B22\" aria-expanded=\"false\" aria-haspopup=\"true\">Farage and Maibach, 2006<\/a>\u00a0).\u00a0\u03a3\u03c4\u03b7\u03bd \u03c0\u03c1\u03b1\u03b3\u03bc\u03b1\u03c4\u03b9\u03ba\u03cc\u03c4\u03b7\u03c4\u03b1, \u03bc\u03cc\u03bb\u03b9\u03c2 \u03be\u03b5\u03ba\u03b9\u03bd\u03ae\u03c3\u03b5\u03b9 \u03b7 \u03b1\u03bd\u03b1\u03c0\u03b1\u03c1\u03b1\u03b3\u03c9\u03b3\u03b9\u03ba\u03ae \u03b7\u03bb\u03b9\u03ba\u03af\u03b1, \u03b7 \u03b1\u03cd\u03be\u03b7\u03c3\u03b7 \u03c4\u03c9\u03bd \u03bf\u03b9\u03c3\u03c4\u03c1\u03bf\u03b3\u03cc\u03bd\u03c9\u03bd \u03c0\u03c1\u03bf\u03ac\u03b3\u03b5\u03b9 \u03c4\u03b7\u03bd \u03c5\u03c0\u03b5\u03c1\u03c0\u03bb\u03b1\u03c3\u03af\u03b1 \u03c4\u03bf\u03c5 \u03b5\u03c0\u03b9\u03b8\u03b7\u03bb\u03af\u03bf\u03c5 \u03c4\u03bf\u03c5 \u03b2\u03bb\u03b5\u03bd\u03bd\u03bf\u03b3\u03cc\u03bd\u03bf\u03c5 \u03c4\u03bf\u03c5 \u03ba\u03cc\u03bb\u03c0\u03bf\u03c5 \u03ba\u03b1\u03b9 \u03b1\u03c5\u03be\u03ac\u03bd\u03b5\u03b9 \u03c4\u03b7\u03bd \u03c0\u03b5\u03c1\u03b9\u03b5\u03ba\u03c4\u03b9\u03ba\u03cc\u03c4\u03b7\u03c4\u03b1 \u03c3\u03b5 \u03ba\u03c5\u03c4\u03c4\u03b1\u03c1\u03b9\u03ba\u03cc \u03b3\u03bb\u03c5\u03ba\u03bf\u03b3\u03cc\u03bd\u03bf (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B2\" aria-expanded=\"false\" aria-haspopup=\"true\">Amabebe and Anumba, 2018<\/a>\u00a0).\u00a0\u03a4\u03bf \u03b3\u03bb\u03c5\u03ba\u03bf\u03b3\u03cc\u03bd\u03bf \u03ba\u03b1\u03c4\u03b1\u03b2\u03bf\u03bb\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03b1\u03bd\u03b8\u03c1\u03ce\u03c0\u03b9\u03bd\u03b7 \u03b1-\u03b1\u03bc\u03c5\u03bb\u03ac\u03c3\u03b7 \u03c3\u03b5 \u03bc\u03b1\u03bb\u03c4\u03cc\u03b6\u03b7, \u03bc\u03b1\u03bb\u03c4\u03bf\u03c4\u03c1\u03b9\u03cc\u03b6\u03b7 \u03ba\u03b1\u03b9 \u03b1-\u03b4\u03b5\u03be\u03c4\u03c1\u03af\u03bd\u03b5\u03c2, \u03ba\u03b1\u03b9 \u03c3\u03c4\u03b7 \u03c3\u03c5\u03bd\u03ad\u03c7\u03b5\u03b9\u03b1 \u03bc\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03c0\u03b5\u03c1\u03b1\u03b9\u03c4\u03ad\u03c1\u03c9 \u03c3\u03b5 \u03b3\u03b1\u03bb\u03b1\u03ba\u03c4\u03b9\u03ba\u03cc \u03bf\u03be\u03cd \u03b1\u03c0\u03cc \u03c4\u03b1 \u03b5\u03af\u03b4\u03b7\u00a0<em>Lactobacillus<\/em>\u00a0(\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B2\" aria-expanded=\"false\" aria-haspopup=\"true\">Amabebe and Anumba, 2018<\/a>\u00a0).\u00a0\u039a\u03b1\u03c4\u03ac \u03c3\u03c5\u03bd\u03ad\u03c0\u03b5\u03b9\u03b1 \u03c4\u03bf \u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03cc pH \u03c6\u03c4\u03ac\u03bd\u03b5\u03b9 \u03c4\u03bf 3,5-4,5, \u03c4\u03bf \u03bf\u03c0\u03bf\u03af\u03bf \u03b5\u03af\u03bd\u03b1\u03b9 \u03ba\u03b1\u03c4\u03ac\u03bb\u03bb\u03b7\u03bb\u03bf \u03b3\u03b9\u03b1 \u03c4\u03b7\u03bd \u03c0\u03c1\u03bf\u03c3\u03ba\u03cc\u03bb\u03bb\u03b7\u03c3\u03b7, \u03c4\u03bf\u03bd \u03b1\u03c0\u03bf\u03b9\u03ba\u03b9\u03c3\u03bc\u03cc \u03ba\u03b1\u03b9 \u03c4\u03b7\u03bd \u03b5\u03c0\u03b9\u03b2\u03af\u03c9\u03c3\u03b7 \u03c4\u03bf\u03c5\u00a0<em>Lactobacillus<\/em>\u00a0\u03ba\u03b1\u03b9 \u03ac\u03bb\u03bb\u03c9\u03bd \u03b2\u03b1\u03ba\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03ce\u03bd \u03b5\u03b9\u03b4\u03ce\u03bd (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B2\" aria-expanded=\"false\" aria-haspopup=\"true\">Amabebe and Anumba, 2018<\/a>\u00a0).\u00a0\u0395\u03c0\u03bf\u03bc\u03ad\u03bd\u03c9\u03c2, \u03c4\u03b1 \u03bf\u03b9\u03c3\u03c4\u03c1\u03bf\u03b3\u03cc\u03bd\u03b1 \u03c0\u03b1\u03af\u03b6\u03bf\u03c5\u03bd \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03cc \u03c1\u03cc\u03bb\u03bf \u03c4\u03cc\u03c3\u03bf \u03c3\u03c4\u03b7 \u03c3\u03cd\u03bd\u03b8\u03b5\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03b9\u03ce\u03bc\u03b1\u03c4\u03bf\u03c2 \u03c4\u03bf\u03c5 \u03ba\u03cc\u03bb\u03c0\u03bf\u03c5 \u03cc\u03c3\u03bf \u03ba\u03b1\u03b9 \u03c3\u03c4\u03bf \u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03cc \u03b5\u03c0\u03b9\u03b8\u03ae\u03bb\u03b9\u03bf: \u03b7 \u03c0\u03c1\u03bf\u03bf\u03b4\u03b5\u03c5\u03c4\u03b9\u03ba\u03ae \u03b1\u03cd\u03be\u03b7\u03c3\u03b7 \u03c4\u03c9\u03bd \u03b5\u03c0\u03b9\u03c0\u03ad\u03b4\u03c9\u03bd \u03bf\u03b9\u03c3\u03c4\u03c1\u03bf\u03b3\u03cc\u03bd\u03c9\u03bd \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03b5\u03c6\u03b7\u03b2\u03b5\u03af\u03b1 \u03c3\u03c4\u03b7\u03bd \u03b1\u03bd\u03b1\u03c0\u03b1\u03c1\u03b1\u03b3\u03c9\u03b3\u03b9\u03ba\u03ae \u03b7\u03bb\u03b9\u03ba\u03af\u03b1 \u03c0\u03c5\u03c1\u03bf\u03b4\u03bf\u03c4\u03b5\u03af \u03c4\u03b7 \u03bc\u03b5\u03c4\u03ac\u03b2\u03b1\u03c3\u03b7 \u03b1\u03c0\u03cc \u03c4\u03b1 \u03c7\u03b1\u03bc\u03b7\u03bb\u03ac \u03b5\u03c0\u03af\u03c0\u03b5\u03b4\u03b1 \u03b3\u03bb\u03c5\u03ba\u03bf\u03b3\u03cc\u03bd\u03bf\u03c5, \u03c4\u03b7\u03bd \u03c5\u03c8\u03b7\u03bb\u03ae \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03b9\u03b1\u03ba\u03ae \u03c0\u03bf\u03b9\u03ba\u03b9\u03bb\u03cc\u03c4\u03b7\u03c4\u03b1, \u03c4\u03bf \u03c5\u03c8\u03b7\u03bb\u03cc \u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03cc pH \u03ba\u03b1\u03b9 \u03c4\u03bf \u03bb\u03b5\u03c0\u03c4\u03cc \u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03cc \u03b5\u03c0\u03b9\u03b8\u03ae\u03bb\u03b9\u03bf \u03ba\u03b1\u03c4\u03ac \u03c4\u03b7\u03bd \u03b5\u03c6\u03b7\u03b2\u03b5\u03af\u03b1, \u03c3\u03b5 \u03c5\u03c8\u03b7\u03bb\u03ad\u03c2 \u03b5\u03bd\u03b1\u03c0\u03bf\u03b8\u03ad\u03c3\u03b5\u03b9\u03c2 \u03b3\u03bb\u03c5\u03ba\u03bf\u03b3\u03cc\u03bd\u03bf\u03c5 \u03c3\u03c4\u03b1 \u03b5\u03c0\u03b9\u03b8\u03b7\u03bb\u03b9\u03b1\u03ba\u03ac \u03ba\u03cd\u03c4\u03c4\u03b1\u03c1\u03b1 \u03ba\u03b1\u03b9 \u03b5\u03bb\u03b5\u03cd\u03b8\u03b5\u03c1\u03bf \u03b3\u03bb\u03c5\u03ba\u03bf\u03b3\u03cc\u03bd\u03bf \u03b4\u03b9\u03b1\u03b8\u03ad\u03c3\u03b9\u03bc\u03bf \u03b3\u03b9\u03b1\u00a0<em>Lactobacillus<\/em>\u00a0spp., \u03c4\u03bf \u03bf\u03c0\u03bf\u03af\u03bf \u03c3\u03c4\u03b7 \u03c3\u03c5\u03bd\u03ad\u03c7\u03b5\u03b9\u03b1 \u03ba\u03c5\u03c1\u03b9\u03b1\u03c1\u03c7\u03b5\u03af \u03c3\u03c4\u03bf \u03c5\u03b3\u03b9\u03ad\u03c2 \u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03cc \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03af\u03c9\u03bc\u03b1 \u03ba\u03b1\u03b9 \u03c0\u03ac\u03c7\u03c5\u03bd\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03bf\u03cd \u03b5\u03c0\u03b9\u03b8\u03b7\u03bb\u03af\u03bf\u03c5 (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B2\" aria-expanded=\"false\" aria-haspopup=\"true\">Amabebe and Anumba, 2018<\/a>\u00a0).<\/p>\n<p>\u039c\u03b9\u03b1 \u03b1\u03bd\u03b9\u03c3\u03bf\u03c1\u03c1\u03bf\u03c0\u03af\u03b1 \u03c3\u03c4\u03b7 \u03c3\u03cd\u03bd\u03b8\u03b5\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03bf\u03cd \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03b9\u03ce\u03bc\u03b1\u03c4\u03bf\u03c2 \u03c3\u03b5 \u03b1\u03c5\u03c4\u03ae\u03bd \u03c4\u03b7\u03bd \u03b7\u03bb\u03b9\u03ba\u03af\u03b1, \u03cc\u03c0\u03c9\u03c2 \u03c3\u03c5\u03bc\u03b2\u03b1\u03af\u03bd\u03b5\u03b9 \u03c3\u03c5\u03bd\u03ae\u03b8\u03c9\u03c2 \u03c3\u03c4\u03b7 \u03b4\u03c5\u03c3\u03b2\u03af\u03c9\u03c3\u03b7, \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03bf\u03b4\u03b7\u03b3\u03ae\u03c3\u03b5\u03b9 \u03c3\u03b5 \u03b2\u03b1\u03ba\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03ae \u03ba\u03bf\u03bb\u03c0\u03af\u03c4\u03b9\u03b4\u03b1, \u03bc\u03b9\u03b1 \u03bc\u03bf\u03bb\u03c5\u03c3\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae \u03b4\u03b9\u03b1\u03b4\u03b9\u03ba\u03b1\u03c3\u03af\u03b1 \u03c0\u03bf\u03c5 \u03bf\u03c1\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ac \u03cc\u03c4\u03b1\u03bd \u03c0\u03bb\u03b7\u03c1\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9 \u03c4\u03c1\u03af\u03b1 \u03b1\u03c0\u03cc \u03c4\u03b1 \u03c4\u03ad\u03c3\u03c3\u03b5\u03c1\u03b1 \u03ba\u03c1\u03b9\u03c4\u03ae\u03c1\u03b9\u03b1 Amsel (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B3\" aria-expanded=\"false\" aria-haspopup=\"true\">Amsel et al., 1983<\/a>\u00a0): i) \u03c5\u03c0\u03b5\u03c1\u03b2\u03bf\u03bb\u03b9\u03ba\u03ae \u03bb\u03b5\u03c5\u03ba\u03ae \u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03ae \u03ad\u03ba\u03ba\u03c1\u03b9\u03c3\u03b7.\u00a0ii) \u03ba\u03b1\u03ba\u03bf\u03c3\u03bc\u03af\u03b1 \u03c8\u03b1\u03c1\u03b9\u03bf\u03cd.\u00a0iii) \u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03ae \u03ad\u03ba\u03ba\u03c1\u03b9\u03c3\u03b7 pH &gt; 4,5;\u00a0iv) \u039a\u03cd\u03c4\u03c4\u03b1\u03c1\u03b1 \u00ab\u03b5\u03bd\u03b4\u03b5\u03af\u03be\u03b5\u03c9\u03bd\u00bb \u03c3\u03b5 \u03c5\u03b3\u03c1\u03ac \u03c0\u03b1\u03c1\u03b1\u03c3\u03ba\u03b5\u03c5\u03ac\u03c3\u03bc\u03b1\u03c4\u03b1.\u00a0\u0388\u03bd\u03b1 \u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03cc \u03c3\u03cd\u03c3\u03c4\u03b7\u03bc\u03b1 \u03b2\u03b1\u03b8\u03bc\u03bf\u03bb\u03cc\u03b3\u03b7\u03c3\u03b7\u03c2, \u03c3\u03c5\u03b3\u03ba\u03b5\u03ba\u03c1\u03b9\u03bc\u03ad\u03bd\u03b1 \u03c4\u03bf Nugent score (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B52\" aria-expanded=\"false\" aria-haspopup=\"true\">Nugent et al., 1991<\/a>\u00a0), \u03c0\u03bf\u03c5 \u03b2\u03b1\u03c3\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03c3\u03c4\u03b7\u03bd \u03c0\u03bf\u03c3\u03bf\u03c4\u03b9\u03ba\u03ae \u03b1\u03be\u03b9\u03bf\u03bb\u03cc\u03b3\u03b7\u03c3\u03b7 \u03c4\u03bf\u03c5\u00a0<em>Lactobacillus<\/em>\u00a0\u03ba\u03b1\u03b9 \u03ac\u03bb\u03bb\u03c9\u03bd \u03bc\u03b9\u03ba\u03c1\u03bf\u03bf\u03c1\u03b3\u03b1\u03bd\u03b9\u03c3\u03bc\u03ce\u03bd (\u00a0<em>Gardenerella vaginalis, Prevotella<\/em>\u00a0spp.\u00a0<em>, Mobiluncus<\/em>\u00a0) \u03c3\u03b5 \u03c7\u03c1\u03c9\u03bc\u03b1\u03c4\u03b9\u03c3\u03bc\u03ad\u03bd\u03bf \u03bc\u03b5 Gram \u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03cc \u03b5\u03c0\u03af\u03c7\u03c1\u03b9\u03c3\u03bc\u03b1, \u03b5\u03c0\u03b9\u03c4\u03c1\u03ad\u03c0\u03b5\u03b9 \u03c4\u03b7\u03bd \u03b1\u03bd\u03af\u03c7\u03bd\u03b5\u03c5\u03c3\u03b7 \u03c0\u03b9\u03bf \u03b5\u03c5\u03b1\u03af\u03c3\u03b8\u03b7\u03c4\u03b7\u03c2 \u03b2\u03b1\u03ba\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03ae \u03ba\u03bf\u03bb\u03c0\u03af\u03c4\u03b9\u03b4\u03b1 \u03c3\u03b5 \u03c3\u03cd\u03b3\u03ba\u03c1\u03b9\u03c3\u03b7 \u03bc\u03cc\u03bd\u03bf \u03bc\u03b5 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ac \u03ba\u03c1\u03b9\u03c4\u03ae\u03c1\u03b9\u03b1 (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B3\" aria-expanded=\"false\" aria-haspopup=\"true\">Amsel et al., 1983<\/a>\u00a0).\u00a0\u03a0\u03c1\u03ac\u03b3\u03bc\u03b1\u03c4\u03b9, \u03c4\u03b1 \u03c5\u03c8\u03b7\u03bb\u03ac \u03b5\u03c0\u03af\u03c0\u03b5\u03b4\u03b1 LAB \u03c3\u03c5\u03bd\u03b4\u03ad\u03bf\u03bd\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03bc\u03b9\u03b1 \u03c5\u03b3\u03b9\u03ae \u03ba\u03b1\u03c4\u03ac\u03c3\u03c4\u03b1\u03c3\u03b7, \u03b5\u03bd\u03ce \u03b7 \u03b5\u03be\u03ac\u03bd\u03c4\u03bb\u03b7\u03c3\u03ae \u03c4\u03bf\u03c5\u03c2 \u03bc\u03b1\u03b6\u03af \u03bc\u03b5 \u03c4\u03bf\u03bd \u03b5\u03c0\u03b9\u03c0\u03bf\u03bb\u03b1\u03c3\u03bc\u03cc \u03ac\u03bb\u03bb\u03c9\u03bd \u03bc\u03bf\u03c1\u03c6\u03bf\u03c4\u03cd\u03c0\u03c9\u03bd \u03c0\u03b1\u03c1\u03b1\u03c4\u03b7\u03c1\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9 \u03c0\u03b9\u03b8\u03b1\u03bd\u03cc\u03c4\u03b5\u03c1\u03b1 \u03c3\u03c4\u03b7 \u03b2\u03b1\u03ba\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03ae \u03ba\u03bf\u03bb\u03c0\u03af\u03c4\u03b9\u03b4\u03b1 (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B52\" aria-expanded=\"false\" aria-haspopup=\"true\">Nugent et al., 1991<\/a>\u00a0).\u00a0\u0393\u03b9\u03b1 \u03bc\u03b5\u03b3\u03ac\u03bb\u03bf \u03c7\u03c1\u03bf\u03bd\u03b9\u03ba\u03cc \u03b4\u03b9\u03ac\u03c3\u03c4\u03b7\u03bc\u03b1, \u03c4\u03b1 \u03c5\u03c8\u03b7\u03bb\u03ac \u03b5\u03c0\u03af\u03c0\u03b5\u03b4\u03b1\u00a0<em>Lactobacillus<\/em>\u00a0\u03c3\u03b5 \u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03cc \u03b5\u03c0\u03af\u03c0\u03b5\u03b4\u03bf \u03c3\u03b5 \u03b3\u03c5\u03bd\u03b1\u03af\u03ba\u03b5\u03c2 \u03b1\u03bd\u03b1\u03c0\u03b1\u03c1\u03b1\u03b3\u03c9\u03b3\u03b9\u03ba\u03ae\u03c2 \u03b7\u03bb\u03b9\u03ba\u03af\u03b1\u03c2 \u03c0\u03b9\u03c3\u03c4\u03b5\u03cd\u03b5\u03c4\u03b1\u03b9 \u03cc\u03c4\u03b9 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c5\u03b3\u03b9\u03ae, \u03b5\u03bd\u03ce \u03bc\u03b9\u03b1 \u03c7\u03b1\u03bc\u03b7\u03bb\u03ae \u03ae \u03b1\u03c0\u03bf\u03c5\u03c3\u03af\u03b1 \u03c3\u03c5\u03b3\u03ba\u03ad\u03bd\u03c4\u03c1\u03c9\u03c3\u03b7\u03c2 \u03ad\u03c7\u03b5\u03b9 \u03b1\u03bd\u03b1\u03b3\u03bd\u03c9\u03c1\u03b9\u03c3\u03c4\u03b5\u03af \u03c9\u03c2 \u03bc\u03b7 \u03b2\u03ad\u03bb\u03c4\u03b9\u03c3\u03c4\u03b7 \u03ba\u03b1\u03c4\u03ac\u03c3\u03c4\u03b1\u03c3\u03b7 (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B57\" aria-expanded=\"false\" aria-haspopup=\"true\">Priestley et al., 1997<\/a>\u00a0).\u00a0\u0397 \u03c5\u03c0\u03cc\u03b8\u03b5\u03c3\u03b7 \u03cc\u03c4\u03b9 \u03c4\u03b1 LAB \u03c3\u03c5\u03bd\u03b5\u03c1\u03b3\u03ac\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03b3\u03b9\u03b1 \u03c4\u03b7 \u03b4\u03b9\u03b1\u03c4\u03ae\u03c1\u03b7\u03c3\u03b7 \u03b5\u03bd\u03cc\u03c2 \u03c5\u03b3\u03b9\u03bf\u03cd\u03c2 \u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03bf\u03cd \u03c0\u03b5\u03c1\u03b9\u03b2\u03ac\u03bb\u03bb\u03bf\u03bd\u03c4\u03bf\u03c2 \u03b2\u03b1\u03c3\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03ba\u03c5\u03c1\u03af\u03c9\u03c2 \u03c3\u03b5 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b5\u03c2\u00a0<em>in vitro<\/em>\u00a0\u03ba\u03b1\u03bb\u03bb\u03b9\u03ad\u03c1\u03b3\u03b5\u03b9\u03b5\u03c2 \u03b2\u03b1\u03ba\u03c4\u03b7\u03c1\u03af\u03c9\u03bd \u03bf\u03b9 \u03bf\u03c0\u03bf\u03af\u03b5\u03c2, \u03b1\u03bd \u03ba\u03b1\u03b9 \u03c0\u03b5\u03c1\u03b9\u03bf\u03c1\u03af\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03bc\u03b5\u03c4\u03b1\u03b2\u03bb\u03b7\u03c4\u03ad\u03c2 \u03c0\u03bf\u03c5 \u03b5\u03be\u03b1\u03c1\u03c4\u03ce\u03bd\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b9\u03c2 \u03c4\u03b5\u03c7\u03bd\u03b9\u03ba\u03ad\u03c2, \u03ad\u03c7\u03bf\u03c5\u03bd \u03c0\u03c1\u03bf\u03c9\u03b8\u03ae\u03c3\u03b5\u03b9 \u03c4\u03b7\u03bd \u03b5\u03c0\u03b9\u03c3\u03c4\u03b7\u03bc\u03bf\u03bd\u03b9\u03ba\u03ae \u03b3\u03bd\u03ce\u03c3\u03b7 \u03b3\u03b9\u03b1 \u03c4\u03b7 \u03c3\u03cd\u03bd\u03b8\u03b5\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03bf\u03cd \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03b9\u03ce\u03bc\u03b1\u03c4\u03bf\u03c2 \u03bc\u03b5 \u03c4\u03b7\u03bd \u03c0\u03ac\u03c1\u03bf\u03b4\u03bf \u03c4\u03c9\u03bd \u03b5\u03c4\u03ce\u03bd (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B31\" aria-expanded=\"false\" aria-haspopup=\"true\">Hay et al., 1997<\/a>\u00a0,\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B36\" aria-expanded=\"false\" aria-haspopup=\"true\">Keane et al., 1997<\/a>\u00a0,\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B68\" aria-expanded=\"false\" aria-haspopup=\"true\">Schwebke et al., 1999<\/a>\u00a0).<\/p>\n<p>\u03a9\u03c3\u03c4\u03cc\u03c3\u03bf, \u03b7 \u03b5\u03bc\u03c6\u03ac\u03bd\u03b9\u03c3\u03b7 \u03bc\u03b5\u03b8\u03cc\u03b4\u03c9\u03bd \u03b1\u03bd\u03b5\u03be\u03ac\u03c1\u03c4\u03b7\u03c4\u03c9\u03bd \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03ba\u03b1\u03bb\u03bb\u03b9\u03ad\u03c1\u03b3\u03b5\u03b9\u03b1, \u03cc\u03c0\u03c9\u03c2 \u03b7 \u03b1\u03bb\u03bb\u03b7\u03bb\u03bf\u03c5\u03c7\u03af\u03b1 \u03b3\u03bf\u03bd\u03b9\u03b4\u03af\u03bf\u03c5 16S rRNA (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B71\" aria-expanded=\"false\" aria-haspopup=\"true\">Stackebrandt and Goebel, 1994<\/a>\u00a0), \u03ad\u03c7\u03b5\u03b9 \u03bf\u03b4\u03b7\u03b3\u03ae\u03c3\u03b5\u03b9 \u03c3\u03b5 \u03bf\u03bb\u03bf\u03ba\u03bb\u03b7\u03c1\u03c9\u03bc\u03ad\u03bd\u03b7 \u03c3\u03cd\u03bb\u03bb\u03b7\u03c8\u03b7 \u03ba\u03b1\u03c4\u03bf\u03b9\u03ba\u03b9\u03ce\u03bd \u03b2\u03b1\u03ba\u03c4\u03b7\u03c1\u03af\u03c9\u03bd \u03c3\u03c4\u03bf\u03bd \u03ba\u03cc\u03bb\u03c0\u03bf (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B4\" aria-expanded=\"false\" aria-haspopup=\"true\">Bakken, 1985<\/a>\u00a0;\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B60\" aria-expanded=\"false\" aria-haspopup=\"true\">Ravel et al., 2011<\/a>\u00a0;\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B54\" aria-expanded=\"false\" aria-haspopup=\"true\">Pasolli et al. ., 2020<\/a>\u00a0).\u00a0\u03a0\u03c1\u03ac\u03b3\u03bc\u03b1\u03c4\u03b9, \u03bc\u03b5 \u03c4\u03b7\u03bd \u03b5\u03ba\u03c4\u03ad\u03bb\u03b5\u03c3\u03b7 \u03bc\u03ad\u03c3\u03c9\u03bd \u03c0\u03c1\u03bf\u03c3\u03b4\u03b9\u03bf\u03c1\u03b9\u03c3\u03bc\u03bf\u03cd \u03b1\u03bb\u03bb\u03b7\u03bb\u03bf\u03c5\u03c7\u03af\u03b1\u03c2 \u03b3\u03bf\u03bd\u03b9\u03b4\u03af\u03bf\u03c5 16S rRNA, \u03bc\u03b9\u03b1 \u03c0\u03c1\u03c9\u03c4\u03bf\u03c0\u03bf\u03c1\u03b9\u03b1\u03ba\u03ae \u03bc\u03b5\u03bb\u03ad\u03c4\u03b7 \u03b1\u03c0\u03cc \u03c4\u03bf\u03c5\u03c2\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B60\" aria-expanded=\"false\" aria-haspopup=\"true\">Ravel et al.\u00a0(2011)<\/a>\u00a0, \u03c0\u03bf\u03c5 \u03b4\u03b9\u03b5\u03be\u03ae\u03c7\u03b8\u03b7 \u03c3\u03b5 \u03bc\u03b9\u03b1 \u03bf\u03bc\u03ac\u03b4\u03b1 396 \u03b1\u03c3\u03c5\u03bc\u03c0\u03c4\u03c9\u03bc\u03b1\u03c4\u03b9\u03ba\u03ce\u03bd \u03ba\u03b1\u03b9 \u03c3\u03b5\u03be\u03bf\u03c5\u03b1\u03bb\u03b9\u03ba\u03ac \u03b5\u03bd\u03b5\u03c1\u03b3\u03ce\u03bd \u03b3\u03c5\u03bd\u03b1\u03b9\u03ba\u03ce\u03bd \u03c4\u03b5\u03c3\u03c3\u03ac\u03c1\u03c9\u03bd \u03b4\u03b9\u03b1\u03c6\u03bf\u03c1\u03b5\u03c4\u03b9\u03ba\u03ce\u03bd \u03b5\u03b8\u03bd\u03bf\u03c4\u03ae\u03c4\u03c9\u03bd, \u03b2\u03c1\u03ae\u03ba\u03b5 \u03bc\u03b9\u03b1 \u03bc\u03c5\u03c1\u03b9\u03ac\u03b4\u03b1 \u03b5\u03bd\u03b4\u03b7\u03bc\u03b9\u03ba\u03ce\u03bd \u03b5\u03b9\u03b4\u03ce\u03bd \u03b2\u03b1\u03ba\u03c4\u03b7\u03c1\u03af\u03c9\u03bd \u03ba\u03b1\u03b9 \u03c0\u03c1\u03cc\u03c4\u03b5\u03b9\u03bd\u03b5 \u03c4\u03b7\u03bd \u03c4\u03b1\u03be\u03b9\u03bd\u03cc\u03bc\u03b7\u03c3\u03b7 \u03c0\u03ad\u03bd\u03c4\u03b5 \u03ba\u03cd\u03c1\u03b9\u03c9\u03bd \u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03ce\u03bd \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03b9\u03b1\u03ba\u03ce\u03bd \u03c5\u03c0\u03bf\u03c4\u03cd\u03c0\u03c9\u03bd, \u03b4\u03b7\u03bb\u03b1\u03b4\u03ae \u03c4\u03bf\u03c5\u03c2 \u03c4\u03cd\u03c0\u03bf\u03c5\u03c2 \u03ba\u03bf\u03b9\u03bd\u03bf\u03c4\u03b9\u03ba\u03ce\u03bd \u03ba\u03b1\u03c4\u03b1\u03c3\u03c4\u03ac\u03c3\u03b5\u03c9\u03bd (CSTs).\u00a0\u039c\u03b5 \u03b2\u03ac\u03c3\u03b7 \u03c4\u03b1 282 taxa \u03c0\u03bf\u03c5 \u03c0\u03c1\u03bf\u03c3\u03b4\u03b9\u03bf\u03c1\u03af\u03c3\u03c4\u03b7\u03ba\u03b1\u03bd, \u03bf\u03b9 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bf\u03bc\u03b1\u03b4\u03bf\u03c0\u03bf\u03b9\u03ae\u03b8\u03b7\u03ba\u03b1\u03bd \u03c3\u03b5 5 \u03b4\u03b9\u03b1\u03ba\u03c1\u03b9\u03c4\u03ad\u03c2 \u03bf\u03bc\u03ac\u03b4\u03b5\u03c2 \u03ba\u03bf\u03b9\u03bd\u03cc\u03c4\u03b7\u03c4\u03b1\u03c2.\u00a0\u03a4\u03b1 CST I, II, III \u03ba\u03b1\u03b9 V, \u03c0\u03bf\u03c5 \u03c3\u03c5\u03bd\u03ae\u03b8\u03c9\u03c2 \u03c3\u03c5\u03bd\u03b4\u03ad\u03bf\u03bd\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03ad\u03bd\u03b1\u03bd \u03c5\u03b3\u03b9\u03ae \u03ba\u03cc\u03bb\u03c0\u03bf, \u03c0\u03bf\u03c5 \u03b2\u03c1\u03ad\u03b8\u03b7\u03ba\u03b1\u03bd \u03c3\u03c4\u03bf 73% \u03c4\u03c9\u03bd \u03b3\u03c5\u03bd\u03b1\u03b9\u03ba\u03ce\u03bd, \u03ba\u03c5\u03c1\u03b9\u03b1\u03c1\u03c7\u03bf\u03cd\u03bd\u03c4\u03b1\u03bd \u03b1\u03c0\u03cc \u03b4\u03b9\u03b1\u03c6\u03bf\u03c1\u03b5\u03c4\u03b9\u03ba\u03ac \u03b5\u03af\u03b4\u03b7 Lactobacilli\u00a0<em>(<\/em>\u00a0L.\u00a0<em>iners, L. crispatus, L. gasseri<\/em>\u00a0\u03ae\u00a0<em>L. jenseni<\/em>\u00a0) \u03ba\u03b1\u03b9 , \u03c0\u03b9\u03bf \u03c0\u03b9\u03b8\u03b1\u03bd\u03cc, \u03b1\u03bd\u03c4\u03b9\u03c0\u03c1\u03bf\u03c3\u03c9\u03c0\u03b5\u03cd\u03bf\u03bd\u03c4\u03b1\u03bd \u03ba\u03c5\u03c1\u03af\u03c9\u03c2 \u03bc\u03b5\u03c4\u03b1\u03be\u03cd \u03c4\u03c9\u03bd \u03b1\u03c3\u03b9\u03b1\u03c4\u03b9\u03ba\u03ce\u03bd \u03ba\u03b1\u03b9 \u03bb\u03b5\u03c5\u03ba\u03ce\u03bd \u03ba\u03bf\u03b9\u03bd\u03bf\u03c4\u03ae\u03c4\u03c9\u03bd (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B60\" aria-expanded=\"false\" aria-haspopup=\"true\">Ravel et al., 2011<\/a>\u00a0).\u00a0\u039c\u03b9\u03b1 \u03c0\u03c1\u03cc\u03c3\u03c6\u03b1\u03c4\u03b7 \u03bc\u03b5\u03b3\u03ac\u03bb\u03b7\u03c2 \u03ba\u03bb\u03af\u03bc\u03b1\u03ba\u03b1\u03c2 \u03b1\u03bd\u03ac\u03bb\u03c5\u03c3\u03b7 \u03b3\u03bf\u03bd\u03b9\u03b4\u03b9\u03c9\u03bc\u03ac\u03c4\u03c9\u03bd LAB \u03b1\u03c0\u03cc \u03c4\u03c1\u03cc\u03c6\u03b9\u03bc\u03b1 \u03ba\u03b1\u03b9 \u03b1\u03bd\u03b8\u03c1\u03ce\u03c0\u03b9\u03bd\u03b1 \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03b9\u03ce\u03bc\u03b1\u03c4\u03b1 \u03ad\u03b4\u03b5\u03b9\u03be\u03b5 \u03cc\u03c4\u03b9 \u03c4\u03b1\u00a0<em>L. crispatus, L. gasseri<\/em>\u00a0\u03ba\u03b1\u03b9\u00a0<em>L. jenseni<\/em>\u00a0\u03b5\u03af\u03bd\u03b1\u03b9 \u03c0\u03c1\u03ac\u03b3\u03bc\u03b1\u03c4\u03b9 \u03c4\u03b1 \u03c0\u03b9\u03bf \u03b4\u03b9\u03b1\u03b4\u03b5\u03b4\u03bf\u03bc\u03ad\u03bd\u03b1 \u03c3\u03b5 \u03b4\u03b5\u03af\u03b3\u03bc\u03b1\u03c4\u03b1 \u03ba\u03cc\u03bb\u03c0\u03bf\u03c5 (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B74\" aria-expanded=\"false\" aria-haspopup=\"true\">Turnbaugh et al., 2007<\/a>\u00a0).\u00a0CST IV, \u03c5\u03c0\u03bf\u03ba\u03b1\u03c4\u03b7\u03b3\u03bf\u03c1\u03bf\u03cd\u03bc\u03b5\u03bd\u03bf \u03c0\u03b5\u03c1\u03b1\u03b9\u03c4\u03ad\u03c1\u03c9 \u03c9\u03c2 IVA \u03ba\u03b1\u03b9 IVB, \u03c0\u03bf\u03c5 \u03c7\u03b1\u03c1\u03b1\u03ba\u03c4\u03b7\u03c1\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03bc\u03b9\u03ba\u03c1\u03cc\u03c4\u03b5\u03c1\u03b7 \u03c0\u03bf\u03c3\u03cc\u03c4\u03b7\u03c4\u03b1 LAB \u03b1\u03bb\u03bb\u03ac \u03c5\u03c8\u03b7\u03bb\u03cc\u03c4\u03b5\u03c1\u03b5\u03c2 \u03b1\u03bd\u03b1\u03bb\u03bf\u03b3\u03af\u03b5\u03c2 \u03b1\u03c5\u03c3\u03c4\u03b7\u03c1\u03ac \u03b1\u03bd\u03b1\u03b5\u03c1\u03cc\u03b2\u03b9\u03c9\u03bd \u03bf\u03c1\u03b3\u03b1\u03bd\u03b9\u03c3\u03bc\u03ce\u03bd (\u00a0<em>Gardnerella, Atopobium, Mobiluncus, Prevotella<\/em>\u00a0\u03ba\u03b1\u03b9\u00a0<em>Leptotrichia<\/em>\u00a0), \u03c3\u03c5\u03b3\u03ba\u03b5\u03bd\u03c4\u03c1\u03ce\u03bd\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c0\u03b5\u03c1\u03b9\u03c3\u03c3\u03cc\u03c4\u03b5\u03c1\u03bf \u03c3\u03c4\u03bf\u03c5\u03c2 \u0399\u03c3\u03c0\u03b1\u03bd\u03cc\u03c6\u03c9\u03bd\u03bf\u03c5\u03c2 \u03ba\u03b1\u03b9 \u03c4\u03bf\u03c5\u03c2 \u039c\u03b1\u03cd\u03c1\u03bf\u03c5\u03c2 \u03ba\u03b1\u03b9 \u03c3\u03c5\u03bd\u03b4\u03ad\u03b8\u03b7\u03ba\u03b1\u03bd \u03bc\u03b5 \u03bc\u03b9\u03b1 \u03ba\u03b1\u03c4\u03ac\u03c3\u03c4\u03b1\u03c3\u03b7 \u03b4\u03c5\u03c3\u03b2\u03af\u03c9\u03c3\u03b7\u03c2 , \u03c5\u03c8\u03b7\u03bb\u03ae \u03b2\u03b1\u03b8\u03bc\u03bf\u03bb\u03bf\u03b3\u03af\u03b1 Nugent \u03ba\u03b1\u03b9 \u03bc\u03b9\u03b1 \u03b1\u03c3\u03c5\u03bc\u03c0\u03c4\u03c9\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae \u03b1\u03bd\u03b8\u03c5\u03b3\u03b9\u03b5\u03b9\u03bd\u03ae \u03ba\u03b1\u03c4\u03ac\u03c3\u03c4\u03b1\u03c3\u03b7 (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B60\" aria-expanded=\"false\" aria-haspopup=\"true\">Ravel et al., 2011<\/a>\u00a0).\u00a0\u0391\u03c5\u03c4\u03ac \u03c4\u03b1 \u03b5\u03c5\u03c1\u03ae\u03bc\u03b1\u03c4\u03b1, \u03c0\u03bf\u03c5 \u03b5\u03c0\u03b9\u03b2\u03b5\u03b2\u03b1\u03b9\u03ce\u03b8\u03b7\u03ba\u03b1\u03bd \u03b1\u03c1\u03b3\u03cc\u03c4\u03b5\u03c1\u03b1 \u03c3\u03b5 \u03ac\u03bb\u03bb\u03b5\u03c2 \u03ad\u03c1\u03b5\u03c5\u03bd\u03b5\u03c2 (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B26\" aria-expanded=\"false\" aria-haspopup=\"true\">Gajer et al., 2012<\/a>\u00a0), \u03ad\u03c7\u03bf\u03c5\u03bd \u03b4\u03b5\u03af\u03be\u03b5\u03b9 \u03cc\u03c4\u03b9 \u03c4\u03bf LAB \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03ad\u03c7\u03b5\u03b9 \u03ba\u03c1\u03af\u03c3\u03b9\u03bc\u03bf \u03c1\u03cc\u03bb\u03bf \u03c3\u03c4\u03b7 \u03b4\u03b9\u03b1\u03c4\u03ae\u03c1\u03b7\u03c3\u03b7 \u03b5\u03bd\u03cc\u03c2 \u03c5\u03b3\u03b9\u03bf\u03cd\u03c2 \u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03bf\u03cd \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03b9\u03ce\u03bc\u03b1\u03c4\u03bf\u03c2.\u00a0\u0395\u03c0\u03b9\u03c0\u03bb\u03ad\u03bf\u03bd, \u03b1\u03c5\u03c4\u03ac \u03c4\u03b1 \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03ad\u03c3\u03bc\u03b1\u03c4\u03b1 \u03ad\u03b4\u03b5\u03b9\u03be\u03b1\u03bd \u03b5\u03c0\u03af\u03c3\u03b7\u03c2 \u03cc\u03c4\u03b9 \u03cc\u03bd\u03c4\u03c9\u03c2 \u03c5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 \u03bc\u03b5\u03c4\u03b1\u03b2\u03bb\u03b7\u03c4\u03cc\u03c4\u03b7\u03c4\u03b1 \u03bc\u03b5\u03c4\u03b1\u03be\u03cd \u03c4\u03c9\u03bd \u03b1\u03c4\u03cc\u03bc\u03c9\u03bd \u03ba\u03b1\u03b9 \u03c0\u03b9\u03b8\u03b1\u03bd\u03cc\u03c4\u03b1\u03c4\u03b1 \u03b2\u03b1\u03c3\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03c3\u03b5 \u03c0\u03bf\u03bb\u03cd\u03c0\u03bb\u03bf\u03ba\u03b5\u03c2 \u03b1\u03bb\u03bb\u03b7\u03bb\u03b5\u03c0\u03b9\u03b4\u03c1\u03ac\u03c3\u03b5\u03b9\u03c2 \u03bc\u03b5\u03c4\u03b1\u03be\u03cd \u03c4\u03c9\u03bd \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03b9\u03b1\u03ba\u03ce\u03bd \u03b5\u03b9\u03b4\u03ce\u03bd \u03ba\u03b1\u03b9 \u03c4\u03bf\u03c5 \u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03bf\u03cd \u03c0\u03b5\u03c1\u03b9\u03b2\u03ac\u03bb\u03bb\u03bf\u03bd\u03c4\u03bf\u03c2.\u00a0\u039a\u03b1\u03b9 \u03c3\u03c4\u03b9\u03c2 \u03b4\u03cd\u03bf \u03bc\u03b5\u03bb\u03ad\u03c4\u03b5\u03c2 (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B74\" aria-expanded=\"false\" aria-haspopup=\"true\">Turnbaugh et al., 2007<\/a>\u00a0;\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B60\" aria-expanded=\"false\" aria-haspopup=\"true\">Ravel et al., 2011<\/a>\u00a0) \u03ba\u03ac\u03b8\u03b5 \u03ba\u03bf\u03b9\u03bd\u03bf\u03c4\u03b9\u03ba\u03cc \u03c3\u03cd\u03bc\u03c0\u03bb\u03b5\u03b3\u03bc\u03b1 \u03ad\u03c7\u03b5\u03b9 \u03b1\u03bd\u03b1\u03c6\u03b5\u03c1\u03b8\u03b5\u03af \u03cc\u03c4\u03b9 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c3\u03c7\u03b5\u03c4\u03b9\u03ba\u03ac \u03c3\u03c4\u03b1\u03b8\u03b5\u03c1\u03cc \u03bc\u03b5 \u03c4\u03b7\u03bd \u03c0\u03ac\u03c1\u03bf\u03b4\u03bf \u03c4\u03bf\u03c5 \u03c7\u03c1\u03cc\u03bd\u03bf\u03c5 \u03c3\u03b5 \u03bf\u03c1\u03b9\u03c3\u03bc\u03ad\u03bd\u03b5\u03c2 \u03c0\u03b5\u03c1\u03b9\u03c0\u03c4\u03ce\u03c3\u03b5\u03b9\u03c2, \u03b5\u03bd\u03ce, \u03c3\u03b5 \u03ac\u03bb\u03bb\u03b5\u03c2 \u03c0\u03b5\u03c1\u03b9\u03c0\u03c4\u03ce\u03c3\u03b5\u03b9\u03c2, \u03bc\u03b9\u03b1 \u03bc\u03b5\u03c4\u03b1\u03c4\u03cc\u03c0\u03b9\u03c3\u03b7 \u03bc\u03b5\u03c4\u03b1\u03be\u03cd \u03c4\u03c9\u03bd CSTs \u03ad\u03c7\u03b5\u03b9 \u03c0\u03b1\u03c1\u03b1\u03c4\u03b7\u03c1\u03b7\u03b8\u03b5\u03af \u03ba\u03b1\u03b9 \u03c3\u03c7\u03b5\u03c4\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03c5\u03c8\u03b7\u03bb\u03cc \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03b9\u03b1\u03ba\u03cc \u03ba\u03cd\u03ba\u03bb\u03bf \u03b5\u03c1\u03b3\u03b1\u03c3\u03b9\u03ce\u03bd.\u00a0\u03a9\u03c3\u03c4\u03cc\u03c3\u03bf, \u03bf\u03b9 \u03b3\u03c5\u03bd\u03b1\u03af\u03ba\u03b5\u03c2 \u03c0\u03bf\u03c5 \u03ac\u03bb\u03bb\u03b1\u03b6\u03b1\u03bd CST \u03b5\u03af\u03c7\u03b1\u03bd \u03ad\u03bd\u03b1 \u03ba\u03b1\u03bb\u03cc \u03cc\u03be\u03b9\u03bd\u03bf \u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03cc \u03c0\u03b5\u03c1\u03b9\u03b2\u03ac\u03bb\u03bb\u03bf\u03bd, \u03b5\u03af\u03c7\u03b1\u03bd \u03ba\u03b1\u03bb\u03ae \u03b1\u03c0\u03cc\u03b4\u03bf\u03c3\u03b7 \u03c3\u03c4\u03bf Nugent (\u03c7\u03b1\u03bc\u03b7\u03bb\u03ae \u03b2\u03b1\u03b8\u03bc\u03bf\u03bb\u03bf\u03b3\u03af\u03b1) \u03ba\u03b1\u03b9 \u03b4\u03b9\u03b1\u03c4\u03b7\u03c1\u03bf\u03cd\u03c3\u03b1\u03bd \u03c5\u03b3\u03b9\u03ae \u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03ae \u03ba\u03b1\u03c4\u03ac\u03c3\u03c4\u03b1\u03c3\u03b7 (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B60\" aria-expanded=\"false\" aria-haspopup=\"true\">Ravel et al., 2011<\/a>\u00a0;\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B26\" aria-expanded=\"false\" aria-haspopup=\"true\">Gajer et al., 2012<\/a>\u00a0).\u00a0\u039c\u03b5\u03c4\u03b1\u03be\u03cd \u03c4\u03c9\u03bd \u03b5\u03b9\u03b4\u03ce\u03bd\u00a0<em>Lactobacillus<\/em>\u00a0,\u00a0<em>\u03c4\u03bf L. iners<\/em>\u03b1\u03bd\u03b1\u03c6\u03ad\u03c1\u03b5\u03c4\u03b1\u03b9 \u03cc\u03c4\u03b9 \u03ad\u03c7\u03b5\u03b9 \u03ad\u03bd\u03b1\u03bd \u03b1\u03bc\u03c6\u03b9\u03bb\u03b5\u03b3\u03cc\u03bc\u03b5\u03bd\u03bf \u03c1\u03cc\u03bb\u03bf \u03c3\u03c4\u03b7 \u03b4\u03b9\u03b1\u03c4\u03ae\u03c1\u03b7\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03bf\u03cd \u03bf\u03b9\u03ba\u03bf\u03c3\u03c5\u03c3\u03c4\u03ae\u03bc\u03b1\u03c4\u03bf\u03c2.\u00a0\u03a4\u03bf \u03b3\u03bf\u03bd\u03b9\u03b4\u03af\u03c9\u03bc\u03ac \u03c4\u03bf\u03c5 \u03ba\u03c9\u03b4\u03b9\u03ba\u03bf\u03c0\u03bf\u03b9\u03b5\u03af \u03c0\u03c1\u03c9\u03c4\u03b5\u0390\u03bd\u03b5\u03c2 \u03c0\u03bf\u03c5 \u03b5\u03bc\u03c0\u03bb\u03ad\u03ba\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c3\u03c4\u03b7 \u03b2\u03ad\u03bb\u03c4\u03b9\u03c3\u03c4\u03b7 \u03c0\u03c1\u03bf\u03c3\u03b1\u03c1\u03bc\u03bf\u03b3\u03ae \u03c3\u03c4\u03b7\u03bd \u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03ae \u03b8\u03ad\u03c3\u03b7, \u03cc\u03c0\u03c9\u03c2 \u03c0\u03c1\u03c9\u03c4\u03b5\u0390\u03bd\u03b5\u03c2 \u03c3\u03b9\u03b4\u03ae\u03c1\u03bf\u03c5-\u03b8\u03b5\u03af\u03bf\u03c5 \u03ba\u03b1\u03b9 \u03bc\u03bf\u03bd\u03b1\u03b4\u03b9\u03ba\u03bf\u03cd\u03c2 \u03c3-\u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b5\u03c2.\u00a0\u03a9\u03c3\u03c4\u03cc\u03c3\u03bf,\u00a0<em>\u03c4\u03bf L. iners<\/em>\u00a0\u03ad\u03c7\u03b5\u03b9 \u03b5\u03c0\u03af\u03c3\u03b7\u03c2 \u03b1\u03c0\u03bf\u03bc\u03bf\u03bd\u03c9\u03b8\u03b5\u03af \u03b1\u03c0\u03cc \u03c4\u03bf \u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03cc \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03af\u03c9\u03bc\u03b1 \u03c4\u03b7\u03c2 \u03b2\u03b1\u03ba\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03ae\u03c2 \u03ba\u03bf\u03bb\u03c0\u03af\u03c4\u03b9\u03b4\u03b1\u03c2, \u03c5\u03c0\u03bf\u03b4\u03b7\u03bb\u03ce\u03bd\u03bf\u03bd\u03c4\u03b1\u03c2 \u03cc\u03c4\u03b9 \u03b1\u03c5\u03c4\u03cc \u03c4\u03bf \u03b5\u03af\u03b4\u03bf\u03c2 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03b5\u03cd\u03ba\u03bf\u03bb\u03b1 \u03bd\u03b1 \u03c0\u03c1\u03bf\u03c3\u03b1\u03c1\u03bc\u03bf\u03c3\u03c4\u03b5\u03af \u03c3\u03c4\u03b7\u03bd \u03ba\u03c5\u03bc\u03b1\u03b9\u03bd\u03cc\u03bc\u03b5\u03bd\u03b7 \u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03ae \u03b8\u03ad\u03c3\u03b7 \u03ae \u03bd\u03b1 \u03bf\u03b4\u03b7\u03b3\u03ae\u03c3\u03b5\u03b9 \u03c3\u03b5 \u03ad\u03bd\u03b1\u03bd \u03c3\u03c5\u03bc\u03b2\u03b9\u03c9\u03c4\u03b9\u03ba\u03cc \u03ae \u03c0\u03b1\u03c1\u03b1\u03c3\u03b9\u03c4\u03b9\u03ba\u03cc \u03c4\u03c1\u03cc\u03c0\u03bf \u03b6\u03c9\u03ae\u03c2.\u00a0<em>\u0397 \u03b2\u03b1\u03ba\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03ae \u03ba\u03bf\u03bb\u03c0\u03af\u03c4\u03b9\u03b4\u03b1 \u03c0\u03bf\u03c5 \u03ba\u03c5\u03c1\u03b9\u03b1\u03c1\u03c7\u03b5\u03af\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03bf L.<\/em>\u00a0\u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03b5\u03c0\u03af\u03c3\u03b7\u03c2 \u03bd\u03b1 \u03c3\u03c7\u03b5\u03c4\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03c5\u03c8\u03b7\u03bb\u03cc\u03c4\u03b5\u03c1\u03bf \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf \u03c0\u03c1\u03cc\u03c9\u03c1\u03bf\u03c5 \u03c4\u03bf\u03ba\u03b5\u03c4\u03bf\u03cd, \u03b5\u03bd\u03b4\u03bf\u03bc\u03b7\u03c4\u03c1\u03af\u03c4\u03b9\u03b4\u03b1\u03c2 \u03ae \u03ac\u03bb\u03bb\u03c9\u03bd \u03bb\u03bf\u03b9\u03bc\u03ce\u03be\u03b5\u03c9\u03bd \u03c4\u03b7\u03c2 \u03b1\u03bd\u03b1\u03c0\u03b1\u03c1\u03b1\u03b3\u03c9\u03b3\u03b9\u03ba\u03ae\u03c2 \u03bf\u03b4\u03bf\u03cd (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B56\" aria-expanded=\"false\" aria-haspopup=\"true\">Petrova et al., 2017<\/a>\u00a0).<\/p>\n<p>\u03a0\u03c1\u03bf\u03c3\u03b8\u03ad\u03c4\u03bf\u03bd\u03c4\u03b1\u03c2 \u03c0\u03bf\u03bb\u03c5\u03c0\u03bb\u03bf\u03ba\u03cc\u03c4\u03b7\u03c4\u03b1 \u03c3\u03c4\u03b7\u03bd \u03b5\u03c4\u03b5\u03c1\u03bf\u03b3\u03ad\u03bd\u03b5\u03b9\u03b1 \u03c4\u03bf\u03c5 \u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03bf\u03cd \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03b9\u03ce\u03bc\u03b1\u03c4\u03bf\u03c2, \u03b1\u03c1\u03ba\u03b5\u03c4\u03ad\u03c2 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b5\u03c2 \u03ad\u03c7\u03bf\u03c5\u03bd \u03c3\u03c5\u03bc\u03c0\u03b5\u03c1\u03b9\u03bb\u03ac\u03b2\u03b5\u03b9 \u03b5\u03c0\u03af\u03c3\u03b7\u03c2 \u03c4\u03b7 \u03b3\u03c5\u03bd\u03b1\u03b9\u03ba\u03b5\u03af\u03b1 \u03c6\u03c5\u03bb\u03ae \u03c9\u03c2 \u03c3\u03c5\u03b3\u03c7\u03c5\u03c4\u03b9\u03ba\u03ae \u03bc\u03b5\u03c4\u03b1\u03b2\u03bb\u03b7\u03c4\u03ae \u03ba\u03b1\u03b9, \u03b5\u03c0\u03bf\u03bc\u03ad\u03bd\u03c9\u03c2, \u03ad\u03c7\u03bf\u03c5\u03bd \u03b1\u03bd\u03b1\u03c6\u03ad\u03c1\u03b5\u03b9 \u03b1\u03bd\u03c4\u03b9\u03c6\u03b1\u03c4\u03b9\u03ba\u03ac \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03ad\u03c3\u03bc\u03b1\u03c4\u03b1 \u03c3\u03c7\u03b5\u03c4\u03b9\u03ba\u03ac \u03bc\u03b5 \u03c4\u03b7\u03bd \u03b5\u03b9\u03b4\u03b9\u03ba\u03cc\u03c4\u03b7\u03c4\u03b1 \u03c4\u03b7\u03c2 \u03c6\u03c5\u03bb\u03ae\u03c2 CST.\u00a0\u03a3\u03c4\u03b7\u03bd \u03c0\u03c1\u03b1\u03b3\u03bc\u03b1\u03c4\u03b9\u03ba\u03cc\u03c4\u03b7\u03c4\u03b1, \u03ba\u03ac\u03b8\u03b5 \u03be\u03b5\u03c7\u03c9\u03c1\u03b9\u03c3\u03c4\u03cc CST \u03b8\u03b1 \u03bc\u03c0\u03bf\u03c1\u03bf\u03cd\u03c3\u03b5 \u03b5\u03cd\u03ba\u03bf\u03bb\u03b1 \u03bd\u03b1 \u03b2\u03c1\u03b5\u03b8\u03b5\u03af \u03c3\u03b5 \u03bf\u03c1\u03b9\u03c3\u03bc\u03ad\u03bd\u03b5\u03c2 \u03b1\u03bd\u03b8\u03c1\u03ce\u03c0\u03b9\u03bd\u03b5\u03c2 \u03c6\u03c5\u03bb\u03ad\u03c2 (\u0399\u03ac\u03c0\u03c9\u03bd\u03b5\u03c2, \u03bb\u03b5\u03c5\u03ba\u03ad\u03c2 \u03ba\u03b1\u03b9 \u03bc\u03b1\u03cd\u03c1\u03b5\u03c2 \u03b3\u03c5\u03bd\u03b1\u03af\u03ba\u03b5\u03c2 \u03c4\u03b7\u03c2 \u0392\u03cc\u03c1\u03b5\u03b9\u03b1\u03c2 \u0391\u03bc\u03b5\u03c1\u03b9\u03ba\u03ae\u03c2) \u03ba\u03b1\u03b9, \u03c9\u03c2 \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1, \u03b7 \u03c3\u03cd\u03bd\u03b8\u03b5\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03b9\u03ce\u03bc\u03b1\u03c4\u03bf\u03c2 \u03c4\u03bf\u03c5 \u03ba\u03cc\u03bb\u03c0\u03bf\u03c5 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b5\u03c0\u03b7\u03c1\u03b5\u03b1\u03c3\u03c4\u03b5\u03af \u03b1\u03c0\u03cc \u03b3\u03b5\u03bd\u03b5\u03c4\u03b9\u03ba\u03ad\u03c2\/\u03b1\u03bd\u03bf\u03c3\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ad\u03c2 \u03b5\u03bd\u03b4\u03b5\u03af\u03be\u03b5\u03b9\u03c2 \u03c0\u03b9\u03bf \u03c0\u03b9\u03b8\u03b1\u03bd\u03cc \u03b1\u03c0\u03cc \u03c4\u03b9\u03c2 \u03ba\u03bf\u03b9\u03bd\u03c9\u03bd\u03b9\u03ba\u03ad\u03c2\/\u03c3\u03c5\u03bc\u03c0\u03b5\u03c1\u03b9\u03c6\u03bf\u03c1\u03b9\u03ba\u03ad\u03c2 \u03c3\u03c5\u03bd\u03ae\u03b8\u03b5\u03b9\u03b5\u03c2.\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B83\" aria-expanded=\"false\" aria-haspopup=\"true\">Zhou et al., 2007<\/a>\u00a0).\u00a0\u0395\u03c0\u03b9\u03c0\u03bb\u03ad\u03bf\u03bd, \u03ad\u03bd\u03b1 \u03b4\u03b5\u03b4\u03bf\u03bc\u03ad\u03bd\u03bf CST \u03b8\u03b1 \u03bc\u03c0\u03bf\u03c1\u03bf\u03cd\u03c3\u03b5 \u03bd\u03b1 \u03c3\u03c5\u03c3\u03c7\u03b5\u03c4\u03b9\u03c3\u03c4\u03b5\u03af \u03bc\u03b5 \u03bc\u03b9\u03b1 \u03b4\u03b5\u03b4\u03bf\u03bc\u03ad\u03bd\u03b7 \u03c6\u03c5\u03bb\u03ae (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B83\" aria-expanded=\"false\" aria-haspopup=\"true\">Zhou et al., 2007<\/a>\u00a0), \u03ba\u03b1\u03b8\u03ce\u03c2, \u03b3\u03b9\u03b1 \u03c0\u03b1\u03c1\u03ac\u03b4\u03b5\u03b9\u03b3\u03bc\u03b1, \u03bf\u03b9 \u03b3\u03c5\u03bd\u03b1\u03af\u03ba\u03b5\u03c2 \u03b5\u03c5\u03c1\u03c9\u03c0\u03b1\u03ca\u03ba\u03ae\u03c2 \u03ba\u03b1\u03c4\u03b1\u03b3\u03c9\u03b3\u03ae\u03c2 \u03c6\u03ad\u03c1\u03bf\u03c5\u03bd \u03b5\u03c5\u03ba\u03bf\u03bb\u03cc\u03c4\u03b5\u03c1\u03b1 \u03ad\u03bd\u03b1 \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03af\u03c9\u03bc\u03b1 \u03c0\u03bf\u03c5 \u03ba\u03c5\u03c1\u03b9\u03b1\u03c1\u03c7\u03b5\u03af\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc\u00a0<em>Lactobacilli<\/em>\u00a0, \u03b5\u03bd\u03ce \u03bf\u03b9 \u03b3\u03c5\u03bd\u03b1\u03af\u03ba\u03b5\u03c2 \u0399\u03c3\u03c0\u03b1\u03bd\u03cc\u03c6\u03c9\u03bd\u03c9\u03bd \u03ba\u03b1\u03b9 \u0391\u03c6\u03c1\u03bf\u03b1\u03bc\u03b5\u03c1\u03b9\u03ba\u03b1\u03bd\u03ce\u03bd \u03b4\u03b5\u03bd \u03c4\u03bf \u03ba\u03ac\u03bd\u03bf\u03c5\u03bd (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B23\" aria-expanded=\"false\" aria-haspopup=\"true\">Fettweis et al., 2014<\/a>\u00a0).<\/p>\n<p>\u03a3\u03c5\u03bd\u03bf\u03bb\u03b9\u03ba\u03ac, \u03b1\u03c5\u03c4\u03ac \u03c4\u03b1 \u03b5\u03c5\u03c1\u03ae\u03bc\u03b1\u03c4\u03b1 \u03c5\u03c0\u03bf\u03b4\u03b7\u03bb\u03ce\u03bd\u03bf\u03c5\u03bd \u03cc\u03c4\u03b9 \u03b7 \u03b1\u03cd\u03be\u03b7\u03c3\u03b7 \u03c4\u03c9\u03bd \u03c3\u03b5\u03be\u03bf\u03c5\u03b1\u03bb\u03b9\u03ba\u03ce\u03bd \u03bf\u03c1\u03bc\u03bf\u03bd\u03ce\u03bd, \u03c4\u03cc\u03c3\u03bf \u03c4\u03c9\u03bd \u03bf\u03b9\u03c3\u03c4\u03c1\u03bf\u03b3\u03cc\u03bd\u03c9\u03bd \u03cc\u03c3\u03bf \u03ba\u03b1\u03b9 \u03c4\u03b7\u03c2 \u03c0\u03c1\u03bf\u03b3\u03b5\u03c3\u03c4\u03af\u03bd\u03b7\u03c2, \u03bc\u03b5\u03c4\u03ac \u03c4\u03b7\u03bd \u03b5\u03bc\u03bc\u03b7\u03bd\u03b1\u03c1\u03c7\u03ae \u03ba\u03b1\u03b9 \u03ba\u03b1\u03c4\u03ac \u03c4\u03b7\u03bd \u03b1\u03bd\u03b1\u03c0\u03b1\u03c1\u03b1\u03b3\u03c9\u03b3\u03b9\u03ba\u03ae \u03b7\u03bb\u03b9\u03ba\u03af\u03b1 \u03c0\u03c1\u03bf\u03ba\u03b1\u03bb\u03b5\u03af \u03ba\u03c1\u03af\u03c3\u03b9\u03bc\u03b5\u03c2 \u03b1\u03bb\u03bb\u03b1\u03b3\u03ad\u03c2 \u03c3\u03c4\u03b7 \u03c3\u03cd\u03bd\u03b8\u03b5\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03b9\u03ce\u03bc\u03b1\u03c4\u03bf\u03c2 \u03c4\u03bf\u03c5 \u03ba\u03cc\u03bb\u03c0\u03bf\u03c5, \u03c4\u03bf \u03bf\u03c0\u03bf\u03af\u03bf \u03c3\u03c5\u03bc\u03b2\u03ac\u03bb\u03bb\u03b5\u03b9 \u03c3\u03c4\u03b7 \u03b4\u03b9\u03b1\u03c4\u03ae\u03c1\u03b7\u03c3\u03b7 \u03b5\u03bd\u03cc\u03c2 \u03c5\u03b3\u03b9\u03bf\u03cd\u03c2 \u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03bf\u03cd \u03c0\u03b5\u03c1\u03b9\u03b2\u03ac\u03bb\u03bb\u03bf\u03bd\u03c4\u03bf\u03c2.\u00a0\u0391\u03c0\u03cc \u03b1\u03c5\u03c4\u03ae \u03c4\u03b7\u03bd \u03ac\u03c0\u03bf\u03c8\u03b7, \u03c4\u03b1 LAB \u03b4\u03b9\u03b1\u03b4\u03c1\u03b1\u03bc\u03b1\u03c4\u03af\u03b6\u03bf\u03c5\u03bd \u03ba\u03c1\u03af\u03c3\u03b9\u03bc\u03bf \u03c1\u03cc\u03bb\u03bf \u03b3\u03b9\u03b1 \u03c4\u03b7\u03bd \u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03ae \u03bf\u03bc\u03bf\u03b9\u03cc\u03c3\u03c4\u03b1\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03b7 \u03b1\u03bd\u03b9\u03c3\u03bf\u03c1\u03c1\u03bf\u03c0\u03af\u03b1 \u03c0\u03c1\u03bf\u03c2 \u03ac\u03bb\u03bb\u03b1 \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03b9\u03b1\u03ba\u03ac \u03b5\u03af\u03b4\u03b7 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03c0\u03c1\u03bf\u03ba\u03b1\u03bb\u03ad\u03c3\u03b5\u03b9 \u03c4\u03b7\u03bd \u03b1\u03bd\u03ac\u03c0\u03c4\u03c5\u03be\u03b7 \u03bc\u03b7 \u03c5\u03b3\u03b9\u03ce\u03bd \u03ba\u03b1\u03c4\u03b1\u03c3\u03c4\u03ac\u03c3\u03b5\u03c9\u03bd.\u00a0\u03a9\u03c3\u03c4\u03cc\u03c3\u03bf, \u03b7 \u03c3\u03cd\u03bd\u03b8\u03b5\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03bf\u03cd \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03b9\u03ce\u03bc\u03b1\u03c4\u03bf\u03c2 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c0\u03bf\u03bb\u03cd \u03b5\u03c4\u03b5\u03c1\u03bf\u03b3\u03b5\u03bd\u03ae\u03c2 \u03bc\u03b5\u03c4\u03b1\u03be\u03cd \u03c4\u03c9\u03bd \u03b1\u03c4\u03cc\u03bc\u03c9\u03bd, \u03ba\u03b1\u03b8\u03ce\u03c2 \u03b5\u03c0\u03b7\u03c1\u03b5\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03b3\u03b5\u03bd\u03b5\u03c4\u03b9\u03ba\u03bf\u03cd\u03c2 \u03ba\u03b1\u03b9 \u03b1\u03bd\u03bf\u03c3\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03bf\u03cd\u03c2 \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b5\u03c2 \u03ba\u03b1\u03b8\u03ce\u03c2 \u03ba\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03b5\u03b8\u03bd\u03b9\u03ba\u03cc\u03c4\u03b7\u03c4\u03b1, \u03b5\u03ba\u03c4\u03cc\u03c2 \u03b1\u03c0\u03cc \u03c4\u03b9\u03c2 \u03ba\u03bf\u03b9\u03bd\u03c9\u03bd\u03b9\u03ba\u03ad\u03c2 \u03c3\u03c5\u03bd\u03ae\u03b8\u03b5\u03b9\u03b5\u03c2 \u03ba\u03b1\u03b9 \u03c4\u03b1 \u03b5\u03c0\u03af\u03c0\u03b5\u03b4\u03b1 \u03bf\u03c1\u03bc\u03bf\u03bd\u03ce\u03bd.<\/p>\n<p>\u03a4\u03bf \u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03cc \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03af\u03c9\u03bc\u03b1 \u03c6\u03ad\u03c1\u03b5\u03c4\u03b1\u03b9 \u03bd\u03b1 \u03c0\u03b1\u03af\u03b6\u03b5\u03b9 \u03ba\u03c1\u03af\u03c3\u03b9\u03bc\u03bf \u03c1\u03cc\u03bb\u03bf \u03ba\u03b1\u03b9 \u03c3\u03c4\u03b9\u03c2 \u03bb\u03bf\u03b9\u03bc\u03ce\u03be\u03b5\u03b9\u03c2 \u03b1\u03c0\u03cc \u03c4\u03bf\u03bd \u03b9\u03cc \u03c4\u03c9\u03bd \u03b1\u03bd\u03b8\u03c1\u03ce\u03c0\u03b9\u03bd\u03c9\u03bd \u03b8\u03b7\u03bb\u03c9\u03bc\u03ac\u03c4\u03c9\u03bd (HPV), \u03c0\u03bf\u03c5 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b3\u03bd\u03c9\u03c3\u03c4\u03cc \u03cc\u03c4\u03b9 \u03c3\u03c7\u03b5\u03c4\u03af\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03c4\u03b7\u03bd \u03b5\u03be\u03ad\u03bb\u03b9\u03be\u03b7 \u03c4\u03bf\u03c5 \u03ba\u03b1\u03c1\u03ba\u03b9\u03bd\u03ce\u03bc\u03b1\u03c4\u03bf\u03c2 \u03c4\u03bf\u03c5 \u03c4\u03c1\u03b1\u03c7\u03ae\u03bb\u03bf\u03c5 \u03c4\u03b7\u03c2 \u03bc\u03ae\u03c4\u03c1\u03b1\u03c2.\u00a0\u0397 \u03c0\u03bf\u03b9\u03ba\u03b9\u03bb\u03bf\u03bc\u03bf\u03c1\u03c6\u03af\u03b1 \u03c4\u03bf\u03c5 \u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03bf\u03cd \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03b9\u03ce\u03bc\u03b1\u03c4\u03bf\u03c2 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b5\u03bc\u03c0\u03bb\u03ad\u03ba\u03b5\u03c4\u03b1\u03b9 \u03c3\u03c4\u03b7 \u03c1\u03cd\u03b8\u03bc\u03b9\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03b5\u03c0\u03b9\u03bc\u03bf\u03bd\u03ae\u03c2 \u03c4\u03bf\u03c5 HPV \u03ba\u03b1\u03b9 \u03c4\u03b7\u03c2 \u03c3\u03bf\u03b2\u03b1\u03c1\u03cc\u03c4\u03b7\u03c4\u03b1\u03c2 \u03c4\u03b7\u03c2 \u03bd\u03cc\u03c3\u03bf\u03c5 \u03c4\u03b7\u03c2 \u03b5\u03bd\u03b4\u03bf\u03b5\u03c0\u03b9\u03b8\u03b7\u03bb\u03b9\u03b1\u03ba\u03ae\u03c2 \u03bd\u03b5\u03bf\u03c0\u03bb\u03b1\u03c3\u03af\u03b1\u03c2 \u03c4\u03bf\u03c5 \u03c4\u03c1\u03b1\u03c7\u03ae\u03bb\u03bf\u03c5 \u03c4\u03b7\u03c2 \u03bc\u03ae\u03c4\u03c1\u03b1\u03c2 (CIN) (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B48\" aria-expanded=\"false\" aria-haspopup=\"true\">Mitra et al., 2015<\/a>\u00a0).\u00a0\u0399\u03b4\u03b9\u03b1\u03af\u03c4\u03b5\u03c1\u03b1, \u03b4\u03b5\u03af\u03b3\u03bc\u03b1\u03c4\u03b1 \u03c0\u03bb\u03b1\u03ba\u03c9\u03b4\u03ce\u03bd \u03b5\u03bd\u03b4\u03bf\u03b5\u03c0\u03b9\u03b8\u03b7\u03bb\u03b9\u03b1\u03ba\u03ce\u03bd \u03b2\u03bb\u03b1\u03b2\u03ce\u03bd \u03c7\u03b1\u03bc\u03b7\u03bb\u03bf\u03cd \u03b2\u03b1\u03b8\u03bc\u03bf\u03cd (LSIL) \u03ad\u03c7\u03bf\u03c5\u03bd \u03b4\u03b5\u03af\u03be\u03b5\u03b9 \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ae \u03c5\u03c0\u03b5\u03c1\u03b5\u03ba\u03c0\u03c1\u03bf\u03c3\u03ce\u03c0\u03b7\u03c3\u03b7 \u03c4\u03c9\u03bd\u00a0<em>Lactobacillus jensenii<\/em>\u00a0\u03ba\u03b1\u03b9\u00a0<em>Lactobacillus coleohominis<\/em>\u00a0.\u00a0\u0394\u03b5\u03af\u03b3\u03bc\u03b1\u03c4\u03b1 \u03c0\u03bb\u03b1\u03ba\u03c9\u03b4\u03ce\u03bd \u03b5\u03bd\u03b4\u03bf\u03b5\u03c0\u03b9\u03b8\u03b7\u03bb\u03b9\u03b1\u03ba\u03ce\u03bd \u03b2\u03bb\u03b1\u03b2\u03ce\u03bd \u03c5\u03c8\u03b7\u03bb\u03bf\u03cd \u03b2\u03b1\u03b8\u03bc\u03bf\u03cd (HSIL) \u03b2\u03c1\u03ad\u03b8\u03b7\u03ba\u03b1\u03bd \u03bd\u03b1 \u03ad\u03c7\u03bf\u03c5\u03bd \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ac \u03c5\u03c8\u03b7\u03bb\u03cc\u03c4\u03b5\u03c1\u03b1 \u03b5\u03c0\u03af\u03c0\u03b5\u03b4\u03b1\u00a0<em>Peptostreptococcus anaerobius<\/em>\u00a0,\u00a0<em>Anaerococcus tetradius<\/em>\u00a0\u03ba\u03b1\u03b9 \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ae \u03c5\u03c0\u03b5\u03c1\u03b5\u03ba\u03c0\u03c1\u03bf\u03c3\u03ce\u03c0\u03b7\u03c3\u03b7 \u03c4\u03c9\u03bd\u00a0<em>Fusobacteria<\/em>\u00a0\u03ba\u03b1\u03b9\u00a0<em>Sneathia sanguinegens<\/em>\u00a0.\u00a0\u0397 \u03b1\u03c5\u03be\u03b1\u03bd\u03cc\u03bc\u03b5\u03bd\u03b7 \u03c3\u03bf\u03b2\u03b1\u03c1\u03cc\u03c4\u03b7\u03c4\u03b1 \u03c4\u03b7\u03c2 \u03bd\u03cc\u03c3\u03bf\u03c5 \u03c3\u03c5\u03c3\u03c7\u03b5\u03c4\u03af\u03c3\u03c4\u03b7\u03ba\u03b5 \u03b5\u03c0\u03af\u03c3\u03b7\u03c2 \u03bc\u03b5 \u03c4\u03b7 \u03bc\u03b5\u03af\u03c9\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03c3\u03c7\u03b5\u03c4\u03b9\u03ba\u03ae\u03c2 \u03b1\u03c6\u03b8\u03bf\u03bd\u03af\u03b1\u03c2 \u03c4\u03bf\u03c5\u00a0<em>Lactobacillus<\/em>\u00a0spp (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B48\" aria-expanded=\"false\" aria-haspopup=\"true\">Mitra et al., 2015<\/a>\u00a0).\u00a0\u039a\u03bf\u03bb\u03c0\u03b9\u03ba\u03ac \u03b4\u03b5\u03af\u03b3\u03bc\u03b1\u03c4\u03b1 \u03c0\u03bf\u03c5 \u03b5\u03bc\u03c6\u03b1\u03bd\u03af\u03b6\u03bf\u03c5\u03bd \u03c7\u03b1\u03bc\u03b7\u03bb\u03ae \u03c3\u03c7\u03b5\u03c4\u03b9\u03ba\u03ae \u03b1\u03c6\u03b8\u03bf\u03bd\u03af\u03b1\u00a0<em>Lactobacillus<\/em>\u00a0spp.\u00a0(\u03cc\u03c0\u03c9\u03c2 \u03c3\u03c4\u03bf CST IV) \u03ae \u03ba\u03c5\u03c1\u03b9\u03b1\u03c1\u03c7\u03bf\u03cd\u03c3\u03b1\u03bd \u03bf\u03b9\u00a0<em>L. iners<\/em>\u00a0(CST III) \u03b5\u03af\u03c7\u03b1\u03bd \u03c4\u03bf \u03bc\u03b5\u03b3\u03b1\u03bb\u03cd\u03c4\u03b5\u03c1\u03bf \u03c0\u03bf\u03c3\u03bf\u03c3\u03c4\u03cc \u03b4\u03b5\u03b9\u03b3\u03bc\u03ac\u03c4\u03c9\u03bd \u03b8\u03b5\u03c4\u03b9\u03ba\u03ce\u03bd \u03b3\u03b9\u03b1 HPV, \u03c5\u03c0\u03bf\u03b4\u03b7\u03bb\u03ce\u03bd\u03bf\u03bd\u03c4\u03b1\u03c2 \u03b1\u03c5\u03be\u03b1\u03bd\u03cc\u03bc\u03b5\u03bd\u03bf \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf \u03b1\u03c0\u03cc\u03ba\u03c4\u03b7\u03c3\u03b7\u03c2 \u03ae\/\u03ba\u03b1\u03b9 \u03b5\u03c0\u03b9\u03bc\u03bf\u03bd\u03ae\u03c2 HPV \u03c3\u03b5 \u03b1\u03c5\u03c4\u03ad\u03c2 \u03c4\u03b9\u03c2 \u03b4\u03cd\u03bf \u03ba\u03b1\u03c4\u03b1\u03c3\u03c4\u03ac\u03c3\u03b5\u03b9\u03c2 (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B9\" aria-expanded=\"false\" aria-haspopup=\"true\">Brotman et al., 2014<\/a>\u00a0).\u00a0\u0391\u03bd\u03c4\u03af\u03b8\u03b5\u03c4\u03b1, \u03bf\u03b9 \u03b3\u03c5\u03bd\u03b1\u03af\u03ba\u03b5\u03c2 \u03bc\u03b5 \u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03ae \u03bc\u03b9\u03ba\u03c1\u03bf\u03c7\u03bb\u03c9\u03c1\u03af\u03b4\u03b1 \u03c0\u03bf\u03c5 \u03ba\u03c5\u03c1\u03b9\u03b1\u03c1\u03c7\u03b5\u03af\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03bf\u00a0<em>L. gasseri<\/em>\u00a0(CST II) \u03b5\u03af\u03c7\u03b1\u03bd \u03c4\u03b1\u03c7\u03cd\u03c4\u03b5\u03c1\u03bf \u03c1\u03c5\u03b8\u03bc\u03cc \u03cd\u03c6\u03b5\u03c3\u03b7\u03c2 \u03c4\u03bf\u03c5 HPV (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B9\" aria-expanded=\"false\" aria-haspopup=\"true\">Brotman et al., 2014<\/a>\u00a0).\u00a0\u039c\u03b9\u03b1 \u03ba\u03bf\u03c1\u03b5\u03b1\u03c4\u03b9\u03ba\u03ae \u03bc\u03b5\u03bb\u03ad\u03c4\u03b7 \u03b5\u03bd\u03c4\u03cc\u03c0\u03b9\u03c3\u03b5 \u03bc\u03b9\u03b1 \u03c0\u03bf\u03b9\u03ba\u03b9\u03bb\u03af\u03b1 \u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03ae\u03c2 \u03bc\u03b9\u03ba\u03c1\u03bf\u03c7\u03bb\u03c9\u03c1\u03af\u03b4\u03b1\u03c2 \u03bc\u03b5\u03c4\u03b1\u03be\u03cd \u03bc\u03bf\u03bd\u03bf\u03b6\u03c5\u03b3\u03c9\u03c4\u03b9\u03ba\u03ce\u03bd \u03b4\u03af\u03b4\u03c5\u03bc\u03c9\u03bd \u03b3\u03c5\u03bd\u03b1\u03b9\u03ba\u03ce\u03bd \u03b1\u03bd\u03ac\u03bb\u03bf\u03b3\u03b1 \u03bc\u03b5 \u03c4\u03b7\u03bd \u03c0\u03b1\u03c1\u03bf\u03c5\u03c3\u03af\u03b1 \u03ae \u03c4\u03b7\u03bd \u03b1\u03c0\u03bf\u03c5\u03c3\u03af\u03b1 \u03c4\u03bf\u03c5 HPV.\u00a0\u039c\u03b9\u03ba\u03c1\u03cc\u03c4\u03b5\u03c1\u03b7 \u03c0\u03b1\u03c1\u03bf\u03c5\u03c3\u03af\u03b1\u00a0<em>Lactobacilli<\/em>\u00a0spp.\u00a0\u03ad\u03c7\u03b5\u03b9 \u03b2\u03c1\u03b5\u03b8\u03b5\u03af \u03c3\u03b5 HPV-\u03b8\u03b5\u03c4\u03b9\u03ba\u03ad\u03c2 \u03b3\u03c5\u03bd\u03b1\u03af\u03ba\u03b5\u03c2, \u03c5\u03c0\u03bf\u03b4\u03b7\u03bb\u03ce\u03bd\u03bf\u03bd\u03c4\u03b1\u03c2 \u03c4\u03b7\u03bd \u03c0\u03b1\u03c1\u03bf\u03c5\u03c3\u03af\u03b1\u00a0<em>Sneathia<\/em>\u00a0s\u00a0<em>pp<\/em>\u00a0\u03c9\u03c2 \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b1 \u03ba\u03b9\u03bd\u03b4\u03cd\u03bd\u03bf\u03c5 \u03b3\u03b9\u03b1 \u03bc\u03cc\u03bb\u03c5\u03bd\u03c3\u03b7 \u03b1\u03c0\u03cc HPV (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B38\" aria-expanded=\"false\" aria-haspopup=\"true\">Lee et al., 2013<\/a>\u00a0).\u00a0\u039c\u03b5 \u03c3\u03c5\u03bd\u03ad\u03c0\u03b5\u03b9\u03b1, \u03c4\u03bf CST IV \u03c6\u03b1\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03bd\u03b1 \u03c3\u03c7\u03b5\u03c4\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03c4\u03b7 \u03bc\u03cc\u03bb\u03c5\u03bd\u03c3\u03b7 \u03b1\u03c0\u03cc HPV, \u03ba\u03b1\u03b8\u03ce\u03c2 \u03c7\u03b1\u03c1\u03b1\u03ba\u03c4\u03b7\u03c1\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03bc\u03b5\u03b3\u03b1\u03bb\u03cd\u03c4\u03b5\u03c1\u03b7 \u03c0\u03bf\u03b9\u03ba\u03b9\u03bb\u03af\u03b1 \u03b5\u03b9\u03b4\u03ce\u03bd \u03b1\u03c0\u03cc \u03ac\u03bb\u03bb\u03b1 CST, \u03bc\u03b5 \u03bc\u03b9\u03ba\u03c1\u03cc\u03c4\u03b5\u03c1\u03b7 \u03c0\u03b1\u03c1\u03bf\u03c5\u03c3\u03af\u03b1\u00a0<em>Lactobacilli<\/em>\u00a0spp.\u00a0\u03c5\u03c0\u03ad\u03c1 \u03c4\u03c9\u03bd \u03b1\u03bd\u03b1\u03b5\u03c1\u03cc\u03b2\u03b9\u03c9\u03bd \u03cc\u03c0\u03c9\u03c2 \u03bf\u03b9\u00a0<em>Gardnerella<\/em>\u00a0,\u00a0<em>Megasphera<\/em>\u00a0,\u00a0<em>Sneathia<\/em>\u00a0\u03ba\u03b1\u03b9\u00a0<em>Prevotella<\/em>\u00a0(\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B66\" aria-expanded=\"false\" aria-haspopup=\"true\">Romero et al., 2014<\/a>\u00a0).\u00a0\u0397 \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03b7 \u03b1\u03bd\u03ac\u03c0\u03c4\u03c5\u03be\u03b7 \u03b1\u03c5\u03c4\u03ce\u03bd \u03c4\u03c9\u03bd \u03b1\u03bd\u03b1\u03b5\u03c1\u03cc\u03b2\u03b9\u03c9\u03bd \u03b5\u03b9\u03b4\u03ce\u03bd \u03ba\u03b1\u03b8\u03bf\u03c1\u03af\u03b6\u03b5\u03b9 \u03c4\u03b7 \u03b2\u03b1\u03ba\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03ae \u03ba\u03bf\u03bb\u03c0\u03af\u03c4\u03b9\u03b4\u03b1, \u03bc\u03b9\u03b1 \u03ba\u03b1\u03c4\u03ac\u03c3\u03c4\u03b1\u03c3\u03b7 \u03c0\u03bf\u03c5 \u03ad\u03c7\u03b5\u03b9 \u03c3\u03c5\u03c3\u03c7\u03b5\u03c4\u03b9\u03c3\u03c4\u03b5\u03af \u03bc\u03b5 \u03c4\u03b7 \u03bc\u03cc\u03bb\u03c5\u03bd\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03c4\u03b7\u03bd \u03b5\u03c0\u03b9\u03bc\u03bf\u03bd\u03ae \u03c4\u03bf\u03c5 HPV \u03ba\u03b1\u03b9 \u03c4\u03b7\u03bd \u03b5\u03c0\u03b1\u03ba\u03cc\u03bb\u03bf\u03c5\u03b8\u03b7 \u03b1\u03bd\u03ac\u03c0\u03c4\u03c5\u03be\u03b7 \u03c4\u03bf\u03c5 CIN (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B28\" aria-expanded=\"false\" aria-haspopup=\"true\">Guo et al., 2012<\/a>\u00a0).<\/p>\n<p>\u03a9\u03c2 \u03b5\u03ba \u03c4\u03bf\u03cd\u03c4\u03bf\u03c5, \u03c3\u03b5 \u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03cc \u03b5\u03c0\u03af\u03c0\u03b5\u03b4\u03bf, \u03c3\u03b5 \u03b1\u03bd\u03c4\u03af\u03b8\u03b5\u03c3\u03b7 \u03bc\u03b5 \u03ac\u03bb\u03bb\u03b5\u03c2 \u03c0\u03b5\u03c1\u03b9\u03bf\u03c7\u03ad\u03c2 \u03c4\u03bf\u03c5 \u03c3\u03ce\u03bc\u03b1\u03c4\u03bf\u03c2, \u03b7 \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03b9\u03b1\u03ba\u03ae \u03bc\u03b5\u03c4\u03b1\u03b2\u03bb\u03b7\u03c4\u03cc\u03c4\u03b7\u03c4\u03b1 \u03c3\u03c7\u03b5\u03c4\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03ba\u03b1\u03c4\u03ac\u03c3\u03c4\u03b1\u03c3\u03b7 \u03b1\u03c3\u03b8\u03ad\u03bd\u03b5\u03b9\u03b1\u03c2 \u03ba\u03b1\u03b9 \u03cc\u03c7\u03b9 \u03bc\u03b5 \u03c5\u03b3\u03b9\u03ae \u03ba\u03b1\u03c4\u03ac\u03c3\u03c4\u03b1\u03c3\u03b7.\u00a0\u0397 \u03b9\u03ba\u03b1\u03bd\u03cc\u03c4\u03b7\u03c4\u03b1 \u03b4\u03b9\u03b1\u03c4\u03ae\u03c1\u03b7\u03c3\u03b7\u03c2 \u03b5\u03bd\u03cc\u03c2 \u03cc\u03be\u03b9\u03bd\u03bf\u03c5 \u03c0\u03b5\u03c1\u03b9\u03b2\u03ac\u03bb\u03bb\u03bf\u03bd\u03c4\u03bf\u03c2 \u03ba\u03b1\u03b9 \u03c0\u03b1\u03c1\u03b1\u03b3\u03c9\u03b3\u03ae\u03c2 \u03b2\u03b1\u03ba\u03c4\u03b7\u03c1\u03b9\u03bf\u03c3\u03af\u03bd\u03b7\u03c2 \u03b5\u03be\u03b7\u03b3\u03b5\u03af \u03c4\u03b7 \u03c3\u03b7\u03bc\u03b1\u03c3\u03af\u03b1 \u03c4\u03b7\u03c2 \u03ba\u03c5\u03c1\u03b9\u03b1\u03c1\u03c7\u03af\u03b1\u03c2 \u03c4\u03bf\u03c5\u00a0<em>Lactobacillus<\/em>\u00a0spp.\u00a0\u03c3\u03b5 \u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03cc \u03b5\u03c0\u03af\u03c0\u03b5\u03b4\u03bf.\u00a0\u039f \u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03cc\u03c2 \u03b2\u03bb\u03b5\u03bd\u03bd\u03bf\u03b3\u03cc\u03bd\u03bf\u03c2 \u03b5\u03af\u03bd\u03b1\u03b9 \u03ad\u03c4\u03c3\u03b9 \u03ac\u03b8\u03b9\u03ba\u03c4\u03bf\u03c2 \u03ba\u03b1\u03b9 \u03c0\u03c1\u03bf\u03c3\u03c4\u03b1\u03c4\u03b5\u03cd\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03b5\u03b9\u03c3\u03b2\u03bf\u03bb\u03ae \u03ac\u03bb\u03bb\u03c9\u03bd \u03bc\u03b9\u03ba\u03c1\u03bf\u03bf\u03c1\u03b3\u03b1\u03bd\u03b9\u03c3\u03bc\u03ce\u03bd \u03cc\u03c0\u03c9\u03c2 \u03bf HPV.\u00a0\u03a0\u03c1\u03ac\u03b3\u03bc\u03b1\u03c4\u03b9, \u03c3\u03b5 \u03ad\u03bd\u03b1\u03bd \u03c0\u03bb\u03b7\u03b8\u03c5\u03c3\u03bc\u03cc 9165 \u03c0\u03c1\u03bf\u03b5\u03bc\u03bc\u03b7\u03bd\u03bf\u03c0\u03b1\u03c5\u03c3\u03b9\u03b1\u03ba\u03ce\u03bd \u03b3\u03c5\u03bd\u03b1\u03b9\u03ba\u03ce\u03bd \u03bc\u03b9\u03b1 \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ae \u03b1\u03cd\u03be\u03b7\u03c3\u03b7 10-20% \u03c3\u03c4\u03b7 \u03c3\u03c5\u03c7\u03bd\u03cc\u03c4\u03b7\u03c4\u03b1 \u03c4\u03b7\u03c2 \u03bb\u03bf\u03af\u03bc\u03c9\u03be\u03b7\u03c2 \u03b1\u03c0\u03cc HPV \u03ad\u03c7\u03b5\u03b9 \u03b2\u03c1\u03b5\u03b8\u03b5\u03af \u03cc\u03c4\u03b9 \u03c3\u03c7\u03b5\u03c4\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03bc\u03b5 pH \u03bc\u03b5\u03b3\u03b1\u03bb\u03cd\u03c4\u03b5\u03c1\u03bf \u03b1\u03c0\u03cc 5 \u03c3\u03b5 \u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03cc \u03b5\u03c0\u03af\u03c0\u03b5\u03b4\u03bf (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B37\" aria-expanded=\"false\" aria-haspopup=\"true\">King et al., 2011<\/a>\u00a0).\u00a0\u0395\u03c0\u03b9\u03c0\u03bb\u03ad\u03bf\u03bd, \u03b7 \u03c0\u03b1\u03c1\u03b1\u03b3\u03c9\u03b3\u03ae \u03b2\u03b1\u03ba\u03c4\u03b7\u03c1\u03b9\u03bf\u03ba\u03c4\u03cc\u03bd\u03c9\u03bd \u03bc\u03bf\u03c1\u03af\u03c9\u03bd \u03ba\u03ac\u03bd\u03b5\u03b9\u00a0<em>Lactobacillus<\/em>\u00a0spp.\u00a0\u03ac\u03be\u03b9\u03bf\u03c2 \u03c0\u03c1\u03bf\u03c3\u03c4\u03ac\u03c4\u03b7\u03c2 \u03c4\u03bf\u03c5 \u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03bf\u03cd \u03c0\u03b5\u03c1\u03b9\u03b2\u03ac\u03bb\u03bb\u03bf\u03bd\u03c4\u03bf\u03c2.\u00a0\u03a3\u03c4\u03b7\u03bd \u03c0\u03c1\u03b1\u03b3\u03bc\u03b1\u03c4\u03b9\u03ba\u03cc\u03c4\u03b7\u03c4\u03b1,\u00a0<em>\u03c4\u03bf L. gasseri<\/em>\u00a0, \u03ba\u03b1\u03b8\u03ce\u03c2 \u03ba\u03b1\u03b9\u00a0<em>\u03c4\u03bf L. crispatus<\/em>\u00a0\u03ba\u03b1\u03b9\u00a0<em>\u03c4\u03bf L. reuteri<\/em>\u00a0\u03b5\u03af\u03bd\u03b1\u03b9 \u03b9\u03ba\u03b1\u03bd\u03ac \u03bd\u03b1 \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03c5\u03bd Gasserin \u03c0\u03bf\u03c5 \u03b4\u03c1\u03b1 \u03c4\u03cc\u03c3\u03bf \u03c3\u03b5 Gram \u03b8\u03b5\u03c4\u03b9\u03ba\u03ac \u03cc\u03c3\u03bf \u03ba\u03b1\u03b9 \u03c3\u03b5 Gram \u03b1\u03c1\u03bd\u03b7\u03c4\u03b9\u03ba\u03ac \u03b2\u03b1\u03ba\u03c4\u03ae\u03c1\u03b9\u03b1 (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B12\" aria-expanded=\"false\" aria-haspopup=\"true\">Clarke et al., 2012<\/a>\u00a0).<\/p>\n<p>\u03a9\u03c3\u03c4\u03cc\u03c3\u03bf, \u03b7 \u03c0\u03b9\u03bf \u03ba\u03bf\u03b9\u03bd\u03ae \u03b2\u03b1\u03ba\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03ae \u03c3\u03b5\u03be\u03bf\u03c5\u03b1\u03bb\u03b9\u03ba\u03ac \u03bc\u03b5\u03c4\u03b1\u03b4\u03b9\u03b4\u03cc\u03bc\u03b5\u03bd\u03b7 \u03bb\u03bf\u03af\u03bc\u03c9\u03be\u03b7 \u03c0\u03b1\u03b3\u03ba\u03bf\u03c3\u03bc\u03af\u03c9\u03c2 \u03b1\u03bd\u03c4\u03b9\u03c0\u03c1\u03bf\u03c3\u03c9\u03c0\u03b5\u03cd\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03bf\u00a0<em>Chlamydia trachomatis<\/em>\u00a0(CT), \u03ad\u03bd\u03b1 Gram-\u03b1\u03c1\u03bd\u03b7\u03c4\u03b9\u03ba\u03cc \u03c5\u03c0\u03bf\u03c7\u03c1\u03b5\u03c9\u03c4\u03b9\u03ba\u03cc \u03b5\u03bd\u03b4\u03bf\u03ba\u03c5\u03c4\u03c4\u03b1\u03c1\u03b9\u03ba\u03cc \u03b2\u03b1\u03ba\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03cc \u03c0\u03b1\u03b8\u03bf\u03b3\u03cc\u03bd\u03bf \u03c0\u03bf\u03c5 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03c0\u03c1\u03bf\u03ba\u03b1\u03bb\u03ad\u03c3\u03b5\u03b9 \u03b1\u03c0\u03bb\u03ad\u03c2 \u03bb\u03bf\u03b9\u03bc\u03ce\u03be\u03b5\u03b9\u03c2 \u03c4\u03bf\u03c5 \u03bf\u03c5\u03c1\u03bf\u03b3\u03b5\u03bd\u03bd\u03b7\u03c4\u03b9\u03ba\u03bf\u03cd \u03c3\u03c5\u03c3\u03c4\u03ae\u03bc\u03b1\u03c4\u03bf\u03c2, \u03c3\u03c5\u03bc\u03c0\u03b5\u03c1\u03b9\u03bb\u03b1\u03bc\u03b2\u03b1\u03bd\u03bf\u03bc\u03ad\u03bd\u03c9\u03bd \u03b1\u03c3\u03c5\u03bc\u03c0\u03c4\u03c9\u03bc\u03b1\u03c4\u03b9\u03ba\u03ce\u03bd \u03bf\u03c5\u03c1\u03bf\u03b3\u03b5\u03bd\u03bd\u03b7\u03c4\u03b9\u03ba\u03ce\u03bd \u03bb\u03bf\u03b9\u03bc\u03ce\u03be\u03b5\u03c9\u03bd \u03cc\u03c0\u03c9\u03c2 \u03bf\u03c5\u03c1\u03b7\u03b8\u03c1\u03af\u03c4\u03b9\u03b4\u03b1 \u03ba\u03b1\u03b9 \u03c4\u03c1\u03b1\u03c7\u03b7\u03bb\u03af\u03c4\u03b9\u03b4\u03b1, \u03c0\u03bf\u03c5 \u03b4\u03c5\u03bd\u03b7\u03c4\u03b9\u03ba\u03ac \u03b5\u03be\u03b5\u03bb\u03af\u03c3\u03c3\u03b5\u03c4\u03b1\u03b9 \u03c3\u03b5 \u03c0\u03b9\u03bf \u03c3\u03bf\u03b2\u03b1\u03c1\u03ad\u03c2 \u03c0\u03c1\u03bf\u03b2\u03bb\u03ae\u03bc\u03b1\u03c4\u03b1 \u03b5\u03ac\u03bd \u03b4\u03b5\u03bd \u03b1\u03bd\u03c4\u03b9\u03bc\u03b5\u03c4\u03c9\u03c0\u03b9\u03c3\u03c4\u03bf\u03cd\u03bd \u03ad\u03b3\u03ba\u03b1\u03b9\u03c1\u03b1, \u03cc\u03c0\u03c9\u03c2 \u03b7 \u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ce\u03b4\u03b7\u03c2 \u03bd\u03cc\u03c3\u03bf\u03c2 \u03c4\u03b7\u03c2 \u03c0\u03c5\u03ad\u03bb\u03bf\u03c5, \u03b7 \u03ad\u03ba\u03c4\u03bf\u03c0\u03b7 \u03ba\u03cd\u03b7\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03b7 \u03c5\u03c0\u03bf\u03b3\u03bf\u03bd\u03b9\u03bc\u03cc\u03c4\u03b7\u03c4\u03b1 (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B49\" aria-expanded=\"false\" aria-haspopup=\"true\">Mitra et al., 2016<\/a>\u00a0;\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B78\" aria-expanded=\"false\" aria-haspopup=\"true\">WHO, 2018<\/a>\u00a0).<\/p>\n<p>\u039f\u03b9 \u03b1\u03bb\u03bb\u03b1\u03b3\u03ad\u03c2 \u03c4\u03bf\u03c5 \u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03bf\u03cd \u03bf\u03b9\u03ba\u03bf\u03c3\u03c5\u03c3\u03c4\u03ae\u03bc\u03b1\u03c4\u03bf\u03c2 \u03ba\u03b1\u03c4\u03ac \u03c4\u03b7 \u03b4\u03b9\u03ac\u03c1\u03ba\u03b5\u03b9\u03b1 \u03ba\u03bf\u03b9\u03bd\u03ce\u03bd \u03bb\u03bf\u03b9\u03bc\u03ce\u03be\u03b5\u03c9\u03bd \u03c4\u03b7\u03c2 \u03b3\u03c5\u03bd\u03b1\u03b9\u03ba\u03b5\u03af\u03b1\u03c2 \u03b3\u03b5\u03bd\u03bd\u03b7\u03c4\u03b9\u03ba\u03ae\u03c2 \u03bf\u03b4\u03bf\u03cd \u03b4\u03b9\u03b5\u03c1\u03b5\u03c5\u03bd\u03ae\u03b8\u03b7\u03ba\u03b1\u03bd \u03c0\u03c1\u03cc\u03c3\u03c6\u03b1\u03c4\u03b1 \u03bc\u03b5 \u03b1\u03bd\u03ac\u03bb\u03c5\u03c3\u03b7 \u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03bf\u03cd \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03b9\u03ce\u03bc\u03b1\u03c4\u03bf\u03c2 \u03ba\u03b1\u03b9 \u03bc\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03b9\u03c3\u03bc\u03bf\u03cd \u03c3\u03b5 79 \u03b3\u03c5\u03bd\u03b1\u03af\u03ba\u03b5\u03c2 \u03b1\u03bd\u03b1\u03c0\u03b1\u03c1\u03b1\u03b3\u03c9\u03b3\u03b9\u03ba\u03ae\u03c2 \u03b7\u03bb\u03b9\u03ba\u03af\u03b1\u03c2, \u03bc\u03ad\u03c3\u03c9 \u03c0\u03c1\u03bf\u03c3\u03b4\u03b9\u03bf\u03c1\u03b9\u03c3\u03bc\u03bf\u03cd \u03b1\u03bb\u03bb\u03b7\u03bb\u03bf\u03c5\u03c7\u03af\u03b1\u03c2 \u03b5\u03c0\u03cc\u03bc\u03b5\u03bd\u03b7\u03c2 \u03b3\u03b5\u03bd\u03b9\u03ac\u03c2 \u03ba\u03b1\u03b9 \u03c6\u03b1\u03c3\u03bc\u03b1\u03c4\u03bf\u03c3\u03ba\u03bf\u03c0\u03af\u03b1\u03c2 \u03bc\u03b1\u03b3\u03bd\u03b7\u03c4\u03b9\u03ba\u03bf\u03cd \u03c3\u03c5\u03bd\u03c4\u03bf\u03bd\u03b9\u03c3\u03bc\u03bf\u03cd \u03c0\u03c5\u03c1\u03b7\u03bd\u03b9\u03ba\u03bf\u03cd \u03c3\u03c5\u03bd\u03c4\u03bf\u03bd\u03b9\u03c3\u03bc\u03bf\u03cd \u03bc\u03b5 \u03b2\u03ac\u03c3\u03b7 \u03c4\u03bf \u03c0\u03c1\u03c9\u03c4\u03cc\u03bd\u03b9\u03bf (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B11\" aria-expanded=\"false\" aria-haspopup=\"true\">Ceccarani et al., 2019<\/a>\u00a0).\u00a0\u039f\u03b9 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03c4\u03b1\u03be\u03b9\u03bd\u03bf\u03bc\u03ae\u03b8\u03b7\u03ba\u03b1\u03bd \u03c9\u03c2 \u03b1\u03b9\u03b4\u03bf\u03b9\u03bf\u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03ae \u03ba\u03b1\u03bd\u03c4\u03b9\u03bd\u03c4\u03af\u03b1\u03c3\u03b7 (VVC, \u03b1\u03c1. 18), \u03bb\u03bf\u03af\u03bc\u03c9\u03be\u03b7\u00a0<em>\u03b1\u03c0\u03cc Chlamydia trachomatis<\/em>\u00a0(CT, \u03b1\u03c1. 20), \u03b2\u03b1\u03ba\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03ae \u03ba\u03bf\u03bb\u03c0\u03af\u03c4\u03b9\u03b4\u03b1 (BV, \u03b1\u03c1. 20) \u03ba\u03b1\u03b9 \u03c5\u03b3\u03b9\u03b5\u03af\u03c2 \u03bc\u03ac\u03c1\u03c4\u03c5\u03c1\u03b5\u03c2 (HC, \u03b1\u03c1. 21) (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B11\" aria-expanded=\"false\" aria-haspopup=\"true\">Ceccarani et al., 2019<\/a>\u00a0).\u00a0<em>\u03a4\u03bf \u03b3\u03ad\u03bd\u03bf\u03c2 Lactobacillus<\/em>\u00a0\u03bc\u03b5\u03b9\u03ce\u03b8\u03b7\u03ba\u03b5 \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ac \u03c3\u03b5 \u03cc\u03bb\u03b5\u03c2 \u03c4\u03b9\u03c2 \u03bb\u03bf\u03b9\u03bc\u03ce\u03be\u03b5\u03b9\u03c2 \u03c4\u03c9\u03bd \u03b3\u03b5\u03bd\u03bd\u03b7\u03c4\u03b9\u03ba\u03ce\u03bd \u03bf\u03c1\u03b3\u03ac\u03bd\u03c9\u03bd.\u00a0\u0397 \u03b1\u03bd\u03ac\u03bb\u03c5\u03c3\u03b7 \u03c3\u03b5 \u03b5\u03c0\u03af\u03c0\u03b5\u03b4\u03bf \u03b5\u03af\u03b4\u03bf\u03c5\u03c2 \u03b1\u03c0\u03bf\u03ba\u03ac\u03bb\u03c5\u03c8\u03b5 \u03cc\u03c4\u03b9 \u03c4\u03bf \u03c5\u03b3\u03b9\u03ad\u03c2 \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03af\u03c9\u03bc\u03b1 \u03c4\u03bf\u03c5 \u03ba\u03cc\u03bb\u03c0\u03bf\u03c5 \u03ba\u03c5\u03c1\u03b9\u03b1\u03c1\u03c7\u03bf\u03cd\u03bd\u03c4\u03b1\u03bd \u03b1\u03c0\u03cc \u03c4\u03bf\u00a0<em>L. crispatus<\/em>\u00a0, \u03b5\u03bd\u03ce \u03b7 \u03bc\u03b5\u03c4\u03b1\u03c4\u03cc\u03c0\u03b9\u03c3\u03b7 \u03b1\u03c0\u03cc HC \u03c3\u03b5 CT, VVC \u03ba\u03b1\u03b9 BV \u03c0\u03c1\u03bf\u03ba\u03ac\u03bb\u03b5\u03c3\u03b5 \u03c4\u03b7\u03bd \u03c0\u03c1\u03bf\u03bf\u03b4\u03b5\u03c5\u03c4\u03b9\u03ba\u03ae \u03b1\u03bd\u03c4\u03b9\u03ba\u03b1\u03c4\u03ac\u03c3\u03c4\u03b1\u03c3\u03b7 \u03b1\u03c0\u03cc\u00a0<em>L. crispatus<\/em>\u00a0\u03c3\u03b5\u00a0<em>L. iners<\/em>\u00a0(\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B11\" aria-expanded=\"false\" aria-haspopup=\"true\">Ceccarani et al., 2019<\/a>\u00a0).\u00a0\u039f\u03b9 VVC, CT \u03ba\u03b1\u03b9 BV \u03ad\u03c7\u03bf\u03c5\u03bd \u03b1\u03bd\u03b1\u03c6\u03b5\u03c1\u03b8\u03b5\u03af \u03cc\u03c4\u03b9 \u03c7\u03b1\u03c1\u03b1\u03ba\u03c4\u03b7\u03c1\u03af\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03b1\u03bd\u03b1\u03b5\u03c1\u03cc\u03b2\u03b9\u03b1 \u03b3\u03ad\u03bd\u03b7, \u03c3\u03c5\u03bc\u03c0\u03b5\u03c1\u03b9\u03bb\u03b1\u03bc\u03b2\u03b1\u03bd\u03bf\u03bc\u03ad\u03bd\u03c9\u03bd.\u00a0<em>Gardnerella<\/em>\u00a0,\u00a0<em>Prevotella<\/em>\u00a0,\u00a0<em>Megasphaera<\/em>\u00a0,\u00a0<em>Roseburia<\/em>\u00a0\u03ba\u03b1\u03b9\u00a0<em>Atopobium<\/em>\u00a0(\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B11\" aria-expanded=\"false\" aria-haspopup=\"true\">Ceccarani et al., 2019<\/a>\u00a0).\u00a0\u0391\u03c5\u03c4\u03ad\u03c2 \u03bf\u03b9 \u03b1\u03bb\u03bb\u03b1\u03b3\u03ad\u03c2 \u03c3\u03c4\u03b9\u03c2 \u03b2\u03b1\u03ba\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03ad\u03c2 \u03ba\u03bf\u03b9\u03bd\u03cc\u03c4\u03b7\u03c4\u03b5\u03c2 \u03ba\u03b1\u03c4\u03ac \u03c4\u03b7 \u03b4\u03b9\u03ac\u03c1\u03ba\u03b5\u03b9\u03b1 \u03c4\u03c9\u03bd \u03bb\u03bf\u03b9\u03bc\u03ce\u03be\u03b5\u03c9\u03bd \u03c4\u03c9\u03bd \u03b3\u03b5\u03bd\u03bd\u03b7\u03c4\u03b9\u03ba\u03ce\u03bd \u03bf\u03c1\u03b3\u03ac\u03bd\u03c9\u03bd \u03b5\u03af\u03c7\u03b1\u03bd \u03c9\u03c2 \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1 \u03c4\u03b7 \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ae \u03bc\u03b5\u03af\u03c9\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03b3\u03b1\u03bb\u03b1\u03ba\u03c4\u03b9\u03ba\u03bf\u03cd \u03ba\u03b1\u03b9 \u03c4\u03b7\u03bd \u03c0\u03b1\u03b8\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ae \u03b1\u03bb\u03bb\u03bf\u03af\u03c9\u03c3\u03b7 \u03c3\u03c4\u03b7 \u03c3\u03cd\u03bd\u03b8\u03b5\u03c3\u03b7 \u03c4\u03c9\u03bd \u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03ce\u03bd \u03bc\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03b9\u03c4\u03ce\u03bd (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B11\" aria-expanded=\"false\" aria-haspopup=\"true\">Ceccarani et al., 2019<\/a>\u00a0).\u00a0\u0391\u03c5\u03c4\u03ac \u03c4\u03b1 \u03b5\u03c5\u03c1\u03ae\u03bc\u03b1\u03c4\u03b1 \u03b5\u03bd\u03b9\u03c3\u03c7\u03cd\u03bf\u03c5\u03bd \u03c4\u03b7\u03bd \u03b1\u03c0\u03cc\u03b4\u03b5\u03b9\u03be\u03b7 \u03cc\u03c4\u03b9 \u03c4\u03bf \u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03cc \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03af\u03c9\u03bc\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03bc\u03b9\u03b1 \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ae \u03ac\u03bc\u03c5\u03bd\u03b1 \u03c0\u03c1\u03ce\u03c4\u03b7\u03c2 \u03b3\u03c1\u03b1\u03bc\u03bc\u03ae\u03c2 \u03b3\u03b9\u03b1 \u03b4\u03b9\u03ac\u03c6\u03bf\u03c1\u03bf\u03c5\u03c2 \u03c4\u03cd\u03c0\u03bf\u03c5\u03c2 \u03bb\u03bf\u03b9\u03bc\u03ce\u03be\u03b5\u03c9\u03bd \u03ba\u03b1\u03b9 \u03bf\u03b9 \u03c4\u03c1\u03bf\u03c0\u03bf\u03c0\u03bf\u03b9\u03ae\u03c3\u03b5\u03b9\u03c2 \u03c4\u03bf\u03c5 \u03bc\u03c0\u03bf\u03c1\u03bf\u03cd\u03bd \u03bd\u03b1 \u03b5\u03c5\u03bd\u03bf\u03ae\u03c3\u03bf\u03c5\u03bd \u03c4\u03b7\u03bd \u03b5\u03b9\u03c3\u03b2\u03bf\u03bb\u03ae \u03bc\u03b9\u03ba\u03c1\u03bf\u03bf\u03c1\u03b3\u03b1\u03bd\u03b9\u03c3\u03bc\u03ce\u03bd.\u00a0\u03a3\u03b5 \u03c5\u03b3\u03b9\u03b5\u03af\u03c2 \u03b3\u03c5\u03bd\u03b1\u03af\u03ba\u03b5\u03c2 \u03c4\u03bf \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03af\u03c9\u03bc\u03b1 \u03b1\u03c6\u03b8\u03bf\u03bd\u03b5\u03af \u03c3\u03b5\u00a0<em>L. crispatus<\/em>\u00a0\u03c0\u03bf\u03c5 \u03ad\u03c7\u03b5\u03b9 \u03b1\u03c0\u03bf\u03b4\u03b5\u03b9\u03c7\u03b8\u03b5\u03af \u03cc\u03c4\u03b9 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c0\u03c1\u03bf\u03c3\u03c4\u03b1\u03c4\u03b5\u03c5\u03c4\u03b9\u03ba\u03cc\u03c2 \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b1\u03c2 \u03b3\u03b9\u03b1 \u03c4\u03b7\u03bd \u03c0\u03c1\u03bf\u03c3\u03ba\u03cc\u03bb\u03bb\u03b7\u03c3\u03b7 CT, \u03c3\u03b5 \u03b1\u03bd\u03c4\u03af\u03b8\u03b5\u03c3\u03b7 \u03bc\u03b5\u00a0<em>\u03c4\u03bf L. iners<\/em>\u00a0(\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B11\" aria-expanded=\"false\" aria-haspopup=\"true\">Ceccarani et al., 2019<\/a>\u00a0).\u00a0\u03a4\u03bf \u03c0\u03c1\u03ce\u03c4\u03bf \u03ad\u03c7\u03b5\u03b9 \u03bc\u03b5\u03b3\u03b1\u03bb\u03cd\u03c4\u03b5\u03c1\u03b7 \u03b9\u03ba\u03b1\u03bd\u03cc\u03c4\u03b7\u03c4\u03b1 \u03bd\u03b1 \u03c0\u03b1\u03c1\u03ac\u03b3\u03b5\u03b9 \u03b3\u03b1\u03bb\u03b1\u03ba\u03c4\u03b9\u03ba\u03cc \u03bf\u03be\u03cd \u03c4\u03cc\u03c3\u03bf L \u03cc\u03c3\u03bf \u03ba\u03b1\u03b9 D \u03b4\u03b9\u03bc\u03b5\u03c1\u03ae \u03ba\u03b1\u03b9 H2O2, \u03b5\u03c0\u03b9\u03c4\u03c1\u03ad\u03c0\u03bf\u03bd\u03c4\u03b1\u03c2 \u03ad\u03bd\u03b1 \u03c0\u03b9\u03bf \u03cc\u03be\u03b9\u03bd\u03bf \u03c0\u03b5\u03c1\u03b9\u03b2\u03ac\u03bb\u03bb\u03bf\u03bd \u03c0\u03bf\u03c5 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b5\u03be\u03bf\u03c5\u03b4\u03b5\u03c4\u03b5\u03c1\u03ce\u03c3\u03b5\u03b9 \u03c4\u03b7 \u03b4\u03c1\u03ac\u03c3\u03b7 \u03c4\u03bf\u03c5 CT \u03bc\u03b5 \u03ba\u03b1\u03c4\u03b1\u03c3\u03c4\u03c1\u03bf\u03c6\u03ae \u03c4\u03bf\u03c5 \u03b5\u03c0\u03b9\u03c6\u03b1\u03bd\u03b5\u03b9\u03b1\u03ba\u03bf\u03cd \u03bc\u03bf\u03c1\u03af\u03bf\u03c5, \u03ba\u03b1\u03c4\u03b1\u03c3\u03c4\u03c1\u03bf\u03c6\u03ae \u03c4\u03b7\u03c2 \u03bc\u03b5\u03bc\u03b2\u03c1\u03ac\u03bd\u03b7\u03c2 \u03ba\u03b1\u03b9 \u03b4\u03b9\u03ac\u03c1\u03c1\u03b7\u03be\u03b7 \u03c4\u03bf\u03c5 \u03b5\u03c3\u03c9\u03c4\u03b5\u03c1\u03b9\u03ba\u03bf\u03cd \u03bc\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03b9\u03c3\u03bc\u03cc (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B6\" aria-expanded=\"false\" aria-haspopup=\"true\">Boskey et al., 1999<\/a>\u00a0;\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B51\" aria-expanded=\"false\" aria-haspopup=\"true\">Nardini et al., 2016<\/a>\u00a0).\u00a0\u03a0\u03c1\u03ac\u03b3\u03bc\u03b1\u03c4\u03b9, \u03bc\u03b9\u03b1 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b7 \u03c0\u03b5\u03c1\u03b9\u03c0\u03c4\u03ce\u03c3\u03b5\u03c9\u03bd \u03b5\u03bb\u03ad\u03b3\u03c7\u03bf\u03c5 \u03ad\u03b4\u03b5\u03b9\u03be\u03b5 \u03cc\u03c4\u03b9 \u03b7 \u03ba\u03bf\u03b9\u03bd\u03cc\u03c4\u03b7\u03c4\u03b1 \u03c0\u03bf\u03c5 \u03ba\u03c5\u03c1\u03b9\u03b1\u03c1\u03c7\u03b5\u03af\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc\u00a0<em>\u03c4\u03bf L. iners<\/em>\u00a0\u03b5\u03af\u03bd\u03b1\u03b9 \u03ad\u03bd\u03b1\u03c2 \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b1\u03c2 \u03ba\u03b9\u03bd\u03b4\u03cd\u03bd\u03bf\u03c5 \u03b3\u03b9\u03b1 \u03bc\u03cc\u03bb\u03c5\u03bd\u03c3\u03b7 \u03bc\u03b5 CT (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B33\" aria-expanded=\"false\" aria-haspopup=\"true\">Houdt et al., 2018<\/a>\u00a0).\u00a0\u0388\u03bd\u03b1\u03c2 \u03ac\u03bb\u03bb\u03bf\u03c2 \u03bc\u03b9\u03ba\u03c1\u03bf\u03bf\u03c1\u03b3\u03b1\u03bd\u03b9\u03c3\u03bc\u03cc\u03c2 \u03c0\u03bf\u03c5 \u03c3\u03c5\u03bd\u03b4\u03ad\u03b5\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03bb\u03bf\u03af\u03bc\u03c9\u03be\u03b7 \u03bc\u03b5 CT \u03b5\u03af\u03bd\u03b1\u03b9 \u03c4\u03bf\u00a0<em>Prevotella<\/em>\u00a0, \u03ba\u03b1\u03b8\u03ce\u03c2 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c0\u03b7\u03b3\u03ae \u03c4\u03c1\u03c5\u03c0\u03c4\u03bf\u03c6\u03ac\u03bd\u03b7\u03c2, \u03b5\u03bd\u03cc\u03c2 \u03b1\u03bc\u03b9\u03bd\u03bf\u03be\u03ad\u03bf\u03c2 \u03b1\u03c0\u03b1\u03c1\u03b1\u03af\u03c4\u03b7\u03c4\u03bf \u03b3\u03b9\u03b1 \u03c4\u03b7\u03bd \u03b1\u03bd\u03ac\u03c0\u03c4\u03c5\u03be\u03b7 \u03c4\u03b7\u03c2 CT (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B85\" aria-expanded=\"false\" aria-haspopup=\"true\">Ziklo et al., 2016<\/a>\u00a0).\u00a0\u0391\u03bd\u03c4\u03af\u03b8\u03b5\u03c4\u03b1, \u03b7 \u03c3\u03c5\u03b3\u03ba\u03ad\u03bd\u03c4\u03c1\u03c9\u03c3\u03b7\u00a0<em>\u03c4\u03bf\u03c5 Lactobacillus<\/em>\u00a0\u03b2\u03c1\u03ad\u03b8\u03b7\u03ba\u03b5 \u03cc\u03c4\u03b9 \u03b4\u03b5\u03bd \u03ac\u03bb\u03bb\u03b1\u03be\u03b5 \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ac \u03ba\u03b1\u03c4\u03ac \u03c4\u03b7 \u03b4\u03b9\u03ac\u03c1\u03ba\u03b5\u03b9\u03b1 \u03c4\u03b7\u03c2 VVC, \u03c9\u03c2 \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1 \u03c4\u03b7\u03c2 \u03c5\u03c0\u03b5\u03c1\u03b2\u03bf\u03bb\u03b9\u03ba\u03ae\u03c2 \u03b1\u03bd\u03ac\u03c0\u03c4\u03c5\u03be\u03b7\u03c2 \u03c4\u03bf\u03c5\u00a0<em>Candida<\/em>\u03b5\u03af\u03b4\u03b7 \u03c0\u03bf\u03c5 \u03c6\u03c5\u03c3\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ac \u03b1\u03c0\u03bf\u03b9\u03ba\u03af\u03b6\u03bf\u03c5\u03bd \u03c4\u03bf \u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03cc \u03c0\u03b5\u03c1\u03b9\u03b2\u03ac\u03bb\u03bb\u03bf\u03bd (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B75\" aria-expanded=\"false\" aria-haspopup=\"true\">Underhill, 2013<\/a>\u00a0).\u00a0\u03a0\u03c1\u03ac\u03b3\u03bc\u03b1\u03c4\u03b9, \u03ba\u03b1\u03c4\u03ac \u03c4\u03b7 \u03b4\u03b9\u03ac\u03c1\u03ba\u03b5\u03b9\u03b1 \u03c4\u03b7\u03c2 VVC, \u03c4\u03bf \u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03cc pH \u03b1\u03bd\u03b1\u03c6\u03ad\u03c1\u03b5\u03c4\u03b1\u03b9 \u03c6\u03c5\u03c3\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03cc (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B80\" aria-expanded=\"false\" aria-haspopup=\"true\">Workowski and Berman, 2010<\/a>\u00a0) \u03ba\u03b1\u03b9\u00a0\u03ad\u03c7\u03b5\u03b9 \u03b2\u03c1\u03b5\u03b8\u03b5\u03af \u03ba\u03c5\u03c1\u03af\u03b1\u03c1\u03c7\u03bf \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03af\u03c9\u03bc\u03b1 \u03c3\u03c4\u03bf\u03c5\u03c2\u00a0<em>Lactobacilli \u03c3\u03b5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 VVC (\u00a0<\/em><a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B81\" aria-expanded=\"false\" aria-haspopup=\"true\">Wu et al., 2017<\/a>\u00a0).\u00a0\u0391\u03c5\u03c4\u03ac \u03c4\u03b1 \u03b4\u03b5\u03b4\u03bf\u03bc\u03ad\u03bd\u03b1 \u03b5\u03c0\u03b9\u03b2\u03b5\u03b2\u03b1\u03b9\u03ce\u03bd\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c3\u03b5 \u03ac\u03bb\u03bb\u03b5\u03c2 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b5\u03c2, \u03c0\u03bf\u03c5 \u03b4\u03b5\u03bd \u03b1\u03bd\u03b1\u03c6\u03ad\u03c1\u03bf\u03c5\u03bd \u03b4\u03b9\u03b1\u03c6\u03bf\u03c1\u03ac \u03c3\u03c4\u03b7 \u03c3\u03cd\u03bd\u03b8\u03b5\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03bf\u03cd \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03b9\u03ce\u03bc\u03b1\u03c4\u03bf\u03c2 \u03bc\u03b5\u03c4\u03b1\u03be\u03cd \u03c5\u03b3\u03b9\u03ce\u03bd \u03b3\u03c5\u03bd\u03b1\u03b9\u03ba\u03ce\u03bd \u03ba\u03b1\u03b9 \u03b5\u03ba\u03b5\u03af\u03bd\u03c9\u03bd \u03bc\u03b5 \u03c3\u03bf\u03b2\u03b1\u03c1\u03ae VVC (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B84\" aria-expanded=\"false\" aria-haspopup=\"true\">Zou et al., 2009<\/a>\u00a0;\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B77\" aria-expanded=\"false\" aria-haspopup=\"true\">Vylkova et al., 2011<\/a>\u00a0) \u03ba\u03b1\u03b9 \u03b4\u03b5\u03bd \u03ad\u03c7\u03b5\u03b9 \u03b5\u03bd\u03c4\u03bf\u03c0\u03b9\u03c3\u03c4\u03b5\u03af \u03c4\u03c5\u03c0\u03b9\u03ba\u03cc \u03c0\u03c1\u03cc\u03c4\u03c5\u03c0\u03bf \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03af\u03c9\u03c3\u03b7\u03c2 \u03ba\u03b1\u03c4\u03ac \u03c4\u03b7 \u03b4\u03b9\u03ac\u03c1\u03ba\u03b5\u03b9\u03b1 \u03c4\u03b7\u03c2 VVC (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B40\" aria-expanded=\"false\" aria-haspopup=\"true\">Liu et al., 2013<\/a>\u00a0).<\/p>\n<p>\u03a4\u03bf \u03b5\u03ac\u03bd \u03b7 \u03c7\u03c1\u03ae\u03c3\u03b7 \u03c0\u03c1\u03bf\u03b2\u03b9\u03bf\u03c4\u03b9\u03ba\u03ce\u03bd \u03b8\u03b1 \u03bc\u03c0\u03bf\u03c1\u03bf\u03cd\u03c3\u03b5 \u03bd\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03c3\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae \u03b3\u03b9\u03b1 \u03c4\u03b7 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u03c4\u03b7\u03c2 \u03b4\u03c5\u03c3\u03b2\u03af\u03c9\u03c3\u03b7\u03c2 \u03c3\u03b5 \u03b3\u03c5\u03bd\u03b1\u03af\u03ba\u03b5\u03c2 \u03b1\u03bd\u03b1\u03c0\u03b1\u03c1\u03b1\u03b3\u03c9\u03b3\u03b9\u03ba\u03ae\u03c2 \u03b7\u03bb\u03b9\u03ba\u03af\u03b1\u03c2 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03ba\u03cc\u03bc\u03b1 \u03c5\u03c0\u03cc \u03b4\u03b9\u03b5\u03c1\u03b5\u03cd\u03bd\u03b7\u03c3\u03b7.\u00a0\u039f\u03c1\u03b9\u03c3\u03bc\u03ad\u03bd\u03b5\u03c2 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b5\u03c2 \u03ad\u03c7\u03bf\u03c5\u03bd \u03c0\u03c1\u03bf\u03c4\u03b5\u03af\u03bd\u03b5\u03b9 \u03ad\u03bd\u03b1\u03bd \u03b1\u03bd\u03b1\u03b4\u03c5\u03cc\u03bc\u03b5\u03bd\u03bf \u03c1\u03cc\u03bb\u03bf \u03b3\u03b9\u03b1 \u03c4\u03b1 \u03c0\u03c1\u03b5\u03b2\u03b9\u03bf\u03c4\u03b9\u03ba\u03ac \u03ba\u03b1\u03b9 \u03c4\u03b1 \u03c0\u03c1\u03bf\u03b2\u03b9\u03bf\u03c4\u03b9\u03ba\u03ac \u03c3\u03c4\u03b7\u03bd \u03b1\u03bd\u03b1\u03b4\u03b9\u03b1\u03bc\u03cc\u03c1\u03c6\u03c9\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03bf\u03cd \u03bc\u03b9\u03ba\u03c1\u03bf\u03c0\u03b5\u03c1\u03b9\u03b2\u03ac\u03bb\u03bb\u03bf\u03bd\u03c4\u03bf\u03c2 \u03c3\u03b5 \u03b3\u03c5\u03bd\u03b1\u03af\u03ba\u03b5\u03c2 \u03b1\u03bd\u03b1\u03c0\u03b1\u03c1\u03b1\u03b3\u03c9\u03b3\u03b9\u03ba\u03ae\u03c2 \u03b7\u03bb\u03b9\u03ba\u03af\u03b1\u03c2 (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B34\" aria-expanded=\"false\" aria-haspopup=\"true\">Huang et al., 2014<\/a>\u00a0;\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B82\" aria-expanded=\"false\" aria-haspopup=\"true\">Xie et al., 2017<\/a>\u00a0).\u00a0\u0391\u03c0\u03cc \u03b1\u03c5\u03c4\u03ae \u03c4\u03b7\u03bd \u03ac\u03c0\u03bf\u03c8\u03b7, \u03bc\u03b9\u03b1 \u03c0\u03c1\u03cc\u03c3\u03c6\u03b1\u03c4\u03b7 \u03bc\u03b5\u03c4\u03b1\u03bd\u03ac\u03bb\u03c5\u03c3\u03b7 Cochrane (<a class=\"fig-table-link figpopup\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/table\/T1\/\" target=\"table\" rel=\"noopener\"><strong>\u03a0\u03af\u03bd\u03b1\u03ba\u03b1\u03c2 1<\/strong><\/a>,\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B82\" aria-expanded=\"false\" aria-haspopup=\"true\">Xie et al., 2017<\/a>\u00a0) \u03b1\u03bd\u03ad\u03bb\u03c5\u03c3\u03b1\u03bd \u03c4\u03bf\u03bd \u03c1\u03cc\u03bb\u03bf \u03c4\u03c9\u03bd \u03c3\u03c5\u03bc\u03c0\u03bb\u03b7\u03c1\u03c9\u03bc\u03ac\u03c4\u03c9\u03bd \u03c0\u03c1\u03bf\u03b2\u03b9\u03bf\u03c4\u03b9\u03ba\u03ce\u03bd \u03c3\u03b5 \u03bc\u03b9\u03b1 \u03bc\u03b5\u03b3\u03ac\u03bb\u03b7 \u03bf\u03bc\u03ac\u03b4\u03b1 \u03b1\u03c3\u03b8\u03b5\u03bd\u03ce\u03bd 1656 \u03bc\u03b7 \u03b5\u03b3\u03ba\u03cd\u03c9\u03bd \u03b3\u03c5\u03bd\u03b1\u03b9\u03ba\u03ce\u03bd \u03c0\u03bf\u03c5 \u03c0\u03c1\u03bf\u03c3\u03b2\u03bb\u03ae\u03b8\u03b7\u03ba\u03b1\u03bd \u03b1\u03c0\u03cc \u03b1\u03b9\u03b4\u03bf\u03b9\u03bf\u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03ae \u03ba\u03b1\u03bd\u03c4\u03b9\u03bd\u03c4\u03af\u03b1\u03c3\u03b7.\u00a0\u0391\u03c5\u03c4\u03ae \u03b7 \u03bf\u03bb\u03bf\u03ba\u03bb\u03b7\u03c1\u03c9\u03bc\u03ad\u03bd\u03b7 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b7 \u03b1\u03c0\u03bf\u03ba\u03ac\u03bb\u03c5\u03c8\u03b5 \u03cc\u03c4\u03b9 \u03bf \u03c3\u03c5\u03bd\u03b4\u03c5\u03b1\u03c3\u03bc\u03cc\u03c2 \u03c0\u03c1\u03bf\u03b2\u03b9\u03bf\u03c4\u03b9\u03ba\u03ce\u03bd \u03bc\u03b5 \u03b1\u03bd\u03c4\u03b9\u03bc\u03c5\u03ba\u03b7\u03c4\u03b9\u03b1\u03c3\u03b9\u03ba\u03ac \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b1\u03bd\u03c4\u03b9\u03c0\u03c1\u03bf\u03c3\u03c9\u03c0\u03b5\u03cd\u03b5\u03b9 \u03bc\u03b9\u03b1 \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03c3\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae \u03c3\u03c4\u03c1\u03b1\u03c4\u03b7\u03b3\u03b9\u03ba\u03ae \u03b5\u03bd\u03ac\u03bd\u03c4\u03b9\u03b1 \u03c3\u03b5 \u03b1\u03c5\u03c4\u03ae \u03c4\u03b7 \u03bb\u03bf\u03b9\u03bc\u03ce\u03b4\u03b7 \u03bd\u03cc\u03c3\u03bf, \u03c3\u03b5 \u03c3\u03cd\u03b3\u03ba\u03c1\u03b9\u03c3\u03b7 \u03bc\u03b5 \u03c4\u03b7 \u03bc\u03bf\u03bd\u03b1\u03b4\u03b9\u03ba\u03ae \u03c7\u03bf\u03c1\u03ae\u03b3\u03b7\u03c3\u03b7 \u03c3\u03c5\u03bc\u03b2\u03b1\u03c4\u03b9\u03ba\u03ce\u03bd \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03c5\u03c4\u03b9\u03ba\u03ce\u03bd \u03bc\u03b5 \u03b1\u03bd\u03c4\u03b9\u03bc\u03c5\u03ba\u03b7\u03c4\u03b9\u03b1\u03ba\u03ac \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03b1 (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B82\" aria-expanded=\"false\" aria-haspopup=\"true\">Xie et al., 2017<\/a>\u00a0).\u00a0\u0395\u03c0\u03b9\u03c0\u03bb\u03ad\u03bf\u03bd, \u03b7 \u03c3\u03c5\u03bd\u03b4\u03c5\u03b1\u03c3\u03bc\u03ad\u03bd\u03b7 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u03bc\u03b5 \u03b1\u03bd\u03c4\u03b9\u03bc\u03c5\u03ba\u03b7\u03c4\u03b9\u03b1\u03ba\u03ac \u03ba\u03b1\u03b9 \u03c0\u03c1\u03bf\u03b2\u03b9\u03bf\u03c4\u03b9\u03ba\u03ac \u03c3\u03c5\u03bc\u03c0\u03bb\u03b7\u03c1\u03ce\u03bc\u03b1\u03c4\u03b1, \u03c0\u03bf\u03c5 \u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03bf\u03bd\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03bf \u03c3\u03c4\u03cc\u03bc\u03b1 \u03ba\u03b1\u03b9 \u03c4\u03bf\u03bd \u03ba\u03cc\u03bb\u03c0\u03bf, \u03b8\u03b1 \u03bc\u03c0\u03bf\u03c1\u03bf\u03cd\u03c3\u03b5 \u03bd\u03b1 \u03b2\u03b5\u03bb\u03c4\u03b9\u03ce\u03c3\u03b5\u03b9 \u03c4\u03b1 \u03b2\u03c1\u03b1\u03c7\u03c5\u03c0\u03c1\u03cc\u03b8\u03b5\u03c3\u03bc\u03b1 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ac \u03ba\u03b1\u03b9 \u03bc\u03c5\u03ba\u03b7\u03c4\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ac \u03c0\u03bf\u03c3\u03bf\u03c3\u03c4\u03ac \u03af\u03b1\u03c3\u03b7\u03c2 \u03c7\u03c9\u03c1\u03af\u03c2 \u03bd\u03b1 \u03b5\u03c0\u03b7\u03c1\u03b5\u03ac\u03c3\u03b5\u03b9 \u03c4\u03b1 \u03bc\u03b1\u03ba\u03c1\u03bf\u03c0\u03c1\u03cc\u03b8\u03b5\u03c3\u03bc\u03b1 \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03ad\u03c3\u03bc\u03b1\u03c4\u03b1 \u03ba\u03b1\u03b9 \u03bd\u03b1 \u03bc\u03b5\u03b9\u03ce\u03c3\u03b5\u03b9 \u03c4\u03bf \u03c0\u03bf\u03c3\u03bf\u03c3\u03c4\u03cc \u03c5\u03c0\u03bf\u03c4\u03c1\u03bf\u03c0\u03ae\u03c2 \u03c3\u03b5 1 \u03bc\u03ae\u03bd\u03b1 \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7\u03c2.\u00a0\u039f\u03bc\u03bf\u03af\u03c9\u03c2, \u03bc\u03b9\u03b1 \u03bc\u03b5\u03b3\u03ac\u03bb\u03b7 \u03bc\u03b5\u03c4\u03b1\u03bd\u03ac\u03bb\u03c5\u03c3\u03b7 \u03c0\u03bf\u03c5 \u03c0\u03b5\u03c1\u03b9\u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03b5\u03b9 12 \u03c4\u03c5\u03c7\u03b1\u03b9\u03bf\u03c0\u03bf\u03b9\u03b7\u03bc\u03ad\u03bd\u03b5\u03c2 \u03b5\u03bb\u03b5\u03b3\u03c7\u03cc\u03bc\u03b5\u03bd\u03b5\u03c2 \u03b4\u03bf\u03ba\u03b9\u03bc\u03ad\u03c2 \u03b3\u03b9\u03b1 \u03c3\u03c5\u03bd\u03bf\u03bb\u03b9\u03ba\u03ac 1.304 \u03c3\u03c5\u03bc\u03bc\u03b5\u03c4\u03ad\u03c7\u03bf\u03bd\u03c4\u03b5\u03c2 \u03ad\u03c7\u03b5\u03b9 \u03b4\u03b5\u03af\u03be\u03b5\u03b9 \u03ba\u03ac\u03c0\u03bf\u03b9\u03b1 \u03b9\u03ba\u03b1\u03bd\u03bf\u03c0\u03bf\u03b9\u03b7\u03c4\u03b9\u03ba\u03ac \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03ad\u03c3\u03bc\u03b1\u03c4\u03b1 \u03c4\u03c9\u03bd \u03c0\u03c1\u03bf\u03b2\u03b9\u03bf\u03c4\u03b9\u03ba\u03ce\u03bd \u03ba\u03b1\u03c4\u03ac \u03c4\u03b7\u03c2 \u03b2\u03b1\u03ba\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03ae\u03c2 \u03ba\u03bf\u03bb\u03c0\u03af\u03c4\u03b9\u03b4\u03b1\u03c2 \u03bc\u03b5 \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ae \u03b2\u03b5\u03bb\u03c4\u03af\u03c9\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03c1\u03c5\u03b8\u03bc\u03bf\u03cd \u03af\u03b1\u03c3\u03b7\u03c2 \u03bc\u03b5\u03c4\u03ac \u03b1\u03c0\u03cc 21 \u03ba\u03b1\u03b9 30 \u03b7\u03bc\u03ad\u03c1\u03b5\u03c2 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1\u03c2 (<a class=\"fig-table-link figpopup\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/table\/T2\/\" target=\"table\" rel=\"noopener\"><strong>\u03a0\u03af\u03bd\u03b1\u03ba\u03b1\u03c2 2<\/strong><\/a>,\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B34\" aria-expanded=\"false\" aria-haspopup=\"true\">Huang et al., 2014<\/a>\u00a0).\u00a0\u03a9\u03c3\u03c4\u03cc\u03c3\u03bf, \u03b1\u03c5\u03c4\u03ac \u03c4\u03b1 \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03ad\u03c3\u03bc\u03b1\u03c4\u03b1 \u03b1\u03be\u03af\u03b6\u03bf\u03c5\u03bd \u03c0\u03b5\u03c1\u03b1\u03b9\u03c4\u03ad\u03c1\u03c9 \u03ba\u03b1\u03b9 \u03b1\u03ba\u03c1\u03b9\u03b2\u03ad\u03c3\u03c4\u03b5\u03c1\u03b5\u03c2 \u03ad\u03c1\u03b5\u03c5\u03bd\u03b5\u03c2, \u03bb\u03cc\u03b3\u03c9 \u03c4\u03c9\u03bd \u03b3\u03b5\u03bd\u03b9\u03ba\u03ce\u03bd \u03b1\u03c0\u03bf\u03b4\u03b5\u03b9\u03ba\u03c4\u03b9\u03ba\u03ce\u03bd \u03c3\u03c4\u03bf\u03b9\u03c7\u03b5\u03af\u03c9\u03bd \u03c7\u03b1\u03bc\u03b7\u03bb\u03ae\u03c2 \u03c0\u03bf\u03b9\u03cc\u03c4\u03b7\u03c4\u03b1\u03c2 \u03c4\u03c9\u03bd \u03b5\u03c1\u03b5\u03c5\u03bd\u03b7\u03c4\u03b9\u03ba\u03ce\u03bd \u03b5\u03c1\u03b3\u03b1\u03c3\u03b9\u03ce\u03bd \u03c0\u03bf\u03c5 \u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c5\u03c0\u03cc\u03c8\u03b7.<\/p>\n<p>\u039f\u03bc\u03bf\u03af\u03c9\u03c2 \u03bc\u03b5 \u03c4\u03b7\u03bd \u03b5\u03c0\u03b9\u03c4\u03c5\u03c7\u03ae \u03c7\u03c1\u03ae\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03bc\u03b5\u03c4\u03b1\u03bc\u03cc\u03c3\u03c7\u03b5\u03c5\u03c3\u03b7\u03c2 \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03af\u03c9\u03bd \u03ba\u03bf\u03c0\u03c1\u03ac\u03bd\u03c9\u03bd \u03c3\u03b5 \u03b5\u03bd\u03c4\u03b5\u03c1\u03b9\u03ba\u03ad\u03c2 \u03bb\u03bf\u03b9\u03bc\u03ce\u03be\u03b5\u03b9\u03c2, \u03c0\u03c1\u03cc\u03c3\u03c6\u03b1\u03c4\u03b1 \u03bf \u03c0\u03b9\u03b8\u03b1\u03bd\u03cc\u03c2 \u03c1\u03cc\u03bb\u03bf\u03c2 \u03c4\u03b7\u03c2 \u03bc\u03b5\u03c4\u03b1\u03bc\u03cc\u03c3\u03c7\u03b5\u03c5\u03c3\u03b7\u03c2 \u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03bf\u03cd \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03b9\u03ce\u03bc\u03b1\u03c4\u03bf\u03c2 (VMT) \u03b1\u03c0\u03cc \u03c5\u03b3\u03b9\u03b5\u03af\u03c2 \u03b4\u03cc\u03c4\u03b5\u03c2 \u03ad\u03c7\u03b5\u03b9 \u03b4\u03b9\u03b5\u03c1\u03b5\u03c5\u03bd\u03b7\u03b8\u03b5\u03af \u03c9\u03c2 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03c5\u03c4\u03b9\u03ba\u03ae \u03b5\u03bd\u03b1\u03bb\u03bb\u03b1\u03ba\u03c4\u03b9\u03ba\u03ae \u03bb\u03cd\u03c3\u03b7 \u03b3\u03b9\u03b1 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 \u03c3\u03c5\u03bc\u03c0\u03c4\u03c9\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae \u03ba\u03b1\u03b9 \u03c5\u03c0\u03bf\u03c4\u03c1\u03bf\u03c0\u03b9\u03ac\u03b6\u03bf\u03c5\u03c3\u03b1 \u03b2\u03b1\u03ba\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03ae \u03ba\u03bf\u03bb\u03c0\u03af\u03c4\u03b9\u03b4\u03b1 ( Lev-Sagie et\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B39\" aria-expanded=\"false\" aria-haspopup=\"true\">al., 2019<\/a>\u00a0).\u00a0\u03a4\u03ad\u03c3\u03c3\u03b5\u03c1\u03b9\u03c2 \u03c3\u03c4\u03bf\u03c5\u03c2 \u03c0\u03ad\u03bd\u03c4\u03b5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03c0\u03bf\u03c5 \u03ad\u03bb\u03b1\u03b2\u03b1\u03bd \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u03b5\u03af\u03c7\u03b1\u03bd \u03c0\u03bb\u03ae\u03c1\u03b7 \u03bc\u03b1\u03ba\u03c1\u03bf\u03c7\u03c1\u03cc\u03bd\u03b9\u03b1 \u03cd\u03c6\u03b5\u03c3\u03b7 \u03bc\u03ad\u03c7\u03c1\u03b9 \u03c4\u03b7\u03bd \u03c4\u03b5\u03bb\u03b5\u03c5\u03c4\u03b1\u03af\u03b1 \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7 \u03c3\u03c4\u03bf\u03c5\u03c2 5-21 \u03bc\u03ae\u03bd\u03b5\u03c2 \u03bc\u03b5\u03c4\u03ac \u03c4\u03b7\u03bd VMT, \u03c0\u03bf\u03c5 \u03c3\u03c7\u03b5\u03c4\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03c4\u03b7\u03bd \u03b1\u03bd\u03b1\u03c3\u03cd\u03c3\u03c4\u03b1\u03c3\u03b7 \u03b5\u03bd\u03cc\u03c2\u00a0\u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03bf\u03cd \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03b9\u03ce\u03bc\u03b1\u03c4\u03bf\u03c2 \u03ba\u03c5\u03c1\u03b9\u03b1\u03c1\u03c7\u03bf\u03cd\u03bc\u03b5\u03bd\u03bf\u03c5 \u03b1\u03c0\u03cc\u00a0<em>Lactobacillus (\u00a0<\/em><a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B39\" aria-expanded=\"false\" aria-haspopup=\"true\">Lev-Sagie et al., 2019<\/a>\u00a0).<\/p>\n<h2 id=\"s4title\" class=\"head no_bottom_margin ui-helper-clearfix\"><span style=\"color: #ff0000;\">\u0395\u03bc\u03bc\u03b7\u03bd\u03cc\u03c0\u03b1\u03c5\u03c3\u03b7<\/span><\/h2>\n<div id=\"s4\" class=\"tsec sec\">\n<p class=\"p p-first\">\u0388\u03bd\u03b1 \u03b5\u03c5\u03c1\u03cd \u03c6\u03ac\u03c3\u03bc\u03b1 \u03c3\u03cd\u03bd\u03b8\u03b5\u03c3\u03b7\u03c2 \u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03bf\u03cd \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03b9\u03ce\u03bc\u03b1\u03c4\u03bf\u03c2 \u03ad\u03c7\u03b5\u03b9 \u03b1\u03c0\u03bf\u03b4\u03b5\u03b9\u03c7\u03b8\u03b5\u03af \u03c3\u03c4\u03b7\u03bd \u03b7\u03bb\u03b9\u03ba\u03af\u03b1 \u03c4\u03b7\u03c2 \u03b5\u03bc\u03bc\u03b7\u03bd\u03cc\u03c0\u03b1\u03c5\u03c3\u03b7\u03c2 \u03ba\u03b1\u03b9 \u03b7 \u03c3\u03c7\u03b5\u03c4\u03b9\u03ba\u03ae \u03b1\u03c6\u03b8\u03bf\u03bd\u03af\u03b1 \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03b9\u03b1\u03ba\u03ce\u03bd \u03b5\u03b9\u03b4\u03ce\u03bd \u03c3\u03c4\u03bf\u03bd \u03ba\u03cc\u03bb\u03c0\u03bf \u03c0\u03bf\u03b9\u03ba\u03af\u03bb\u03bb\u03b5\u03b9 \u03c3\u03b5 \u03bc\u03b5\u03b3\u03ac\u03bb\u03bf \u03b2\u03b1\u03b8\u03bc\u03cc \u03bc\u03b5\u03c4\u03b1\u03be\u03cd \u03c4\u03c9\u03bd \u03b3\u03c5\u03bd\u03b1\u03b9\u03ba\u03ce\u03bd (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B70\" aria-expanded=\"false\" aria-haspopup=\"true\">Srinivasan et al., 2010<\/a>\u00a0;\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B9\" aria-expanded=\"false\" aria-haspopup=\"true\">Brotman et al., 2014<\/a>\u00a0).\u00a0\u0395\u03c0\u03b9\u03c0\u03bb\u03ad\u03bf\u03bd, \u03c4\u03bf \u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03cc \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03af\u03c9\u03bc\u03b1 \u03ad\u03c7\u03b5\u03b9 \u03b1\u03bd\u03b1\u03c6\u03b5\u03c1\u03b8\u03b5\u03af \u03cc\u03c4\u03b9 \u03c0\u03b1\u03af\u03b6\u03b5\u03b9 \u03ba\u03c1\u03af\u03c3\u03b9\u03bc\u03bf \u03c1\u03cc\u03bb\u03bf \u03c3\u03c4\u03b9\u03c2 \u03bc\u03b5\u03c4\u03b5\u03bc\u03bc\u03b7\u03bd\u03bf\u03c0\u03b1\u03c5\u03c3\u03b9\u03b1\u03ba\u03ad\u03c2 \u03b3\u03c5\u03bd\u03b1\u03af\u03ba\u03b5\u03c2, \u03ba\u03c5\u03c1\u03af\u03c9\u03c2 \u03b5\u03c0\u03b5\u03b9\u03b4\u03ae \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b1\u03c3\u03ba\u03ae\u03c3\u03b5\u03b9 \u03b2\u03b1\u03b8\u03b9\u03ac \u03b5\u03c0\u03af\u03b4\u03c1\u03b1\u03c3\u03b7 \u03c3\u03c4\u03b7\u03bd \u03b1\u03bd\u03ac\u03c0\u03c4\u03c5\u03be\u03b7 \u03b1\u03b9\u03b4\u03bf\u03b9\u03bf\u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03ae\u03c2 \u03b1\u03c4\u03c1\u03bf\u03c6\u03af\u03b1\u03c2, \u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03ae\u03c2 \u03be\u03b7\u03c1\u03cc\u03c4\u03b7\u03c4\u03b1\u03c2 \u03ba\u03b1\u03b9 \u03bc\u03b5\u03b9\u03c9\u03bc\u03ad\u03bd\u03b7\u03c2 \u03c3\u03b5\u03be\u03bf\u03c5\u03b1\u03bb\u03b9\u03ba\u03ae\u03c2 \u03c5\u03b3\u03b5\u03af\u03b1\u03c2 (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B50\" aria-expanded=\"false\" aria-haspopup=\"true\">Muhleisen and Herbst-Kralovetz, 2016<\/a>\u00a0).<\/p>\n<p>\u0393\u03b5\u03bd\u03b9\u03ba\u03ac, \u03b7 \u03bc\u03b5\u03af\u03c9\u03c3\u03b7 \u03c4\u03c9\u03bd \u03b5\u03c0\u03b9\u03c0\u03ad\u03b4\u03c9\u03bd LAB \u03c3\u03b5 \u03bc\u03b5\u03c4\u03b5\u03bc\u03bc\u03b7\u03bd\u03bf\u03c0\u03b1\u03c5\u03c3\u03b9\u03b1\u03ba\u03ad\u03c2 \u03b3\u03c5\u03bd\u03b1\u03af\u03ba\u03b5\u03c2 \u03b8\u03b5\u03c9\u03c1\u03b5\u03af\u03c4\u03b1\u03b9 \u03c6\u03c5\u03c3\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ae \u03b1\u03bb\u03bb\u03b1\u03b3\u03ae (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B50\" aria-expanded=\"false\" aria-haspopup=\"true\">Muhleisen and Herbst-Kralovetz, 2016<\/a>\u00a0).\u00a0\u03a4\u03bf 1997 \u03bf\u03b9 Hillier et al.\u00a0\u03b4\u03b9\u03b5\u03c1\u03b5\u03cd\u03bd\u03b7\u03c3\u03b5 \u03c4\u03b7 \u03bc\u03b9\u03ba\u03c1\u03bf\u03c7\u03bb\u03c9\u03c1\u03af\u03b4\u03b1 \u03c4\u03bf\u03c5 \u03ba\u03cc\u03bb\u03c0\u03bf\u03c5 \u03c3\u03b5 73 \u03bc\u03b5\u03c4\u03b5\u03bc\u03bc\u03b7\u03bd\u03bf\u03c0\u03b1\u03c5\u03c3\u03b9\u03b1\u03ba\u03ad\u03c2 \u03b3\u03c5\u03bd\u03b1\u03af\u03ba\u03b5\u03c2, \u03bf\u03b9 \u03bf\u03c0\u03bf\u03af\u03b5\u03c2 \u03b4\u03b5\u03bd \u03b5\u03af\u03c7\u03b1\u03bd \u03bb\u03ac\u03b2\u03b5\u03b9 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u03bf\u03c1\u03bc\u03bf\u03bd\u03b9\u03ba\u03ae\u03c2 \u03c5\u03c0\u03bf\u03ba\u03b1\u03c4\u03ac\u03c3\u03c4\u03b1\u03c3\u03b7\u03c2 (HRT) (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B32\" aria-expanded=\"false\" aria-haspopup=\"true\">Hillier and Lau, 1997<\/a>\u00a0).\u00a0<em>\u0393\u03b1\u03bb\u03b1\u03ba\u03c4\u03bf\u03b2\u03ac\u03ba\u03b9\u03bb\u03bb\u03bf\u03b9<\/em>\u00a0\u03b1\u03bd\u03b9\u03c7\u03bd\u03b5\u03cd\u03b8\u03b7\u03ba\u03b1\u03bd \u03c3\u03c4\u03bf 49% \u03c4\u03c9\u03bd \u03b3\u03c5\u03bd\u03b1\u03b9\u03ba\u03ce\u03bd, \u03b5\u03bd\u03ce\u00a0<em>Gardnerella vaginalis<\/em>\u00a0\u03b2\u03c1\u03ad\u03b8\u03b7\u03ba\u03b5 \u03c3\u03c4\u03bf 27%,\u00a0<em>Ureaplasma urealyticum<\/em>\u00a0\u03c3\u03c4\u03bf 13%,\u00a0<em>Candida albicans<\/em>\u00a0\u03c3\u03c4\u03bf 1% \u03ba\u03b1\u03b9\u00a0<em>Prevotella bivia<\/em>\u00a0\u03c3\u03c4\u03bf 33% \u03c4\u03c9\u03bd \u03b3\u03c5\u03bd\u03b1\u03b9\u03ba\u03ce\u03bd (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B23\" aria-expanded=\"false\" aria-haspopup=\"true\">Fettweis et al., 2014<\/a>\u00a0).\u00a0\u0391\u03c5\u03c4\u03ae \u03b7 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b7 \u03ba\u03b1\u03c4\u03ad\u03bb\u03b7\u03be\u03b5 \u03c3\u03c4\u03bf \u03c3\u03c5\u03bc\u03c0\u03ad\u03c1\u03b1\u03c3\u03bc\u03b1 \u03cc\u03c4\u03b9 \u03c4\u03b1 \u03b5\u03af\u03b4\u03b7\u00a0<em>Lactobacillus<\/em>\u00a0\u03ba\u03b1\u03b9 \u03ac\u03bb\u03bb\u03b1 \u03b2\u03b1\u03ba\u03c4\u03ae\u03c1\u03b9\u03b1 \u03c0\u03bf\u03c5 \u03c3\u03c7\u03b5\u03c4\u03af\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03c4\u03b7\u03bd \u03ba\u03bf\u03bb\u03c0\u03af\u03c4\u03b9\u03b4\u03b1 \u03ae\u03c4\u03b1\u03bd \u03bb\u03b9\u03b3\u03cc\u03c4\u03b5\u03c1\u03bf \u03c3\u03c5\u03c7\u03bd\u03ac \u03c3\u03b5 \u03bc\u03b5\u03c4\u03b5\u03bc\u03bc\u03b7\u03bd\u03bf\u03c0\u03b1\u03c5\u03c3\u03b9\u03b1\u03ba\u03ad\u03c2 \u03b3\u03c5\u03bd\u03b1\u03af\u03ba\u03b5\u03c2 \u03b1\u03c0\u03cc \u03b5\u03ba\u03b5\u03af\u03bd\u03b1 \u03c0\u03bf\u03c5 \u03b2\u03c1\u03ad\u03b8\u03b7\u03ba\u03b1\u03bd \u03c3\u03b5 \u03b3\u03c5\u03bd\u03b1\u03af\u03ba\u03b5\u03c2 \u03c3\u03b5 \u03b3\u03cc\u03bd\u03b9\u03bc\u03b7 \u03b7\u03bb\u03b9\u03ba\u03af\u03b1 (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B32\" aria-expanded=\"false\" aria-haspopup=\"true\">Hillier and Lau, 1997<\/a>\u00a0).\u00a0\u039f\u03bc\u03bf\u03af\u03c9\u03c2, \u03bf \u03b5\u03c0\u03b9\u03c0\u03bf\u03bb\u03b1\u03c3\u03bc\u03cc\u03c2 \u03c4\u03b7\u03c2 \u03b2\u03b1\u03ba\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03ae\u03c2 \u03ba\u03bf\u03bb\u03c0\u03af\u03c4\u03b9\u03b4\u03b1\u03c2 \u03ad\u03c7\u03b5\u03b9 \u03b1\u03bd\u03b1\u03c6\u03b5\u03c1\u03b8\u03b5\u03af \u03c3\u03c5\u03bd\u03bf\u03bb\u03b9\u03ba\u03ac \u03c7\u03b1\u03bc\u03b7\u03bb\u03cc\u03c4\u03b5\u03c1\u03bf\u03c2 \u03c3\u03b5 \u03bc\u03b5\u03c4\u03b5\u03bc\u03bc\u03b7\u03bd\u03bf\u03c0\u03b1\u03c5\u03c3\u03b9\u03b1\u03ba\u03ad\u03c2 \u03b3\u03c5\u03bd\u03b1\u03af\u03ba\u03b5\u03c2 (6,0%) \u03b1\u03c0\u03cc \u03cc,\u03c4\u03b9 \u03c3\u03b5 \u03b3\u03cc\u03bd\u03b9\u03bc\u03b5\u03c2 (9,8%) \u03ba\u03b1\u03b9 \u03c0\u03b5\u03c1\u03b9\u03b5\u03bc\u03bc\u03b7\u03bd\u03bf\u03c0\u03b1\u03c5\u03c3\u03b9\u03b1\u03ba\u03ad\u03c2 (11%) \u03b3\u03c5\u03bd\u03b1\u03af\u03ba\u03b5\u03c2 (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B10\" aria-expanded=\"false\" aria-haspopup=\"true\">Cauci et al., 2002<\/a>\u00a0).\u00a0\u0399\u03b4\u03b9\u03b1\u03af\u03c4\u03b5\u03c1\u03b1, \u03c4\u03bf 6,3% \u03c4\u03c9\u03bd \u03bc\u03b5\u03c4\u03b5\u03bc\u03bc\u03b7\u03bd\u03bf\u03c0\u03b1\u03c5\u03c3\u03b9\u03b1\u03ba\u03ce\u03bd \u03b3\u03c5\u03bd\u03b1\u03b9\u03ba\u03ce\u03bd \u03c0\u03bf\u03c5 \u03b4\u03b5\u03bd \u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03bf\u03c5\u03bd HRT \u03ba\u03b1\u03b9 \u03c4\u03bf 5,4% \u03b1\u03c5\u03c4\u03ce\u03bd \u03c0\u03bf\u03c5 \u03ad\u03bb\u03b1\u03b2\u03b1\u03bd \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u03bc\u03b5 HRT \u03ad\u03c7\u03bf\u03c5\u03bd \u03b2\u03c1\u03b5\u03b8\u03b5\u03af \u03b8\u03b5\u03c4\u03b9\u03ba\u03ad\u03c2 \u03b3\u03b9\u03b1 \u03b2\u03b1\u03ba\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03ae \u03ba\u03bf\u03bb\u03c0\u03af\u03c4\u03b9\u03b4\u03b1 (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B10\" aria-expanded=\"false\" aria-haspopup=\"true\">Cauci et al., 2002<\/a>\u00a0).\u00a0\u0395\u03c0\u03bf\u03bc\u03ad\u03bd\u03c9\u03c2, \u03b7 \u03b5\u03c0\u03b1\u03bd\u03b1\u03c6\u03bf\u03c1\u03ac \u03c4\u03b7\u03c2 \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03b9\u03b1\u03ba\u03ae\u03c2 \u03c0\u03bf\u03b9\u03ba\u03b9\u03bb\u03cc\u03c4\u03b7\u03c4\u03b1\u03c2 \u03c4\u03bf\u03c5 LAB \u03c3\u03b5 \u03c0\u03c1\u03bf\u03b5\u03bc\u03bc\u03b7\u03bd\u03bf\u03c0\u03b1\u03c5\u03c3\u03b9\u03b1\u03ba\u03ac \u03b5\u03c0\u03af\u03c0\u03b5\u03b4\u03b1 \u03bc\u03b5\u03c4\u03ac \u03b1\u03c0\u03cc HRT \u03ad\u03c7\u03b5\u03b9 \u03b1\u03c0\u03bf\u03b4\u03b5\u03b9\u03c7\u03b8\u03b5\u03af \u03cc\u03c4\u03b9 \u03b4\u03b5\u03bd \u03b1\u03c5\u03be\u03ac\u03bd\u03b5\u03b9 \u03c4\u03bf\u03bd \u03b5\u03c0\u03b9\u03c0\u03bf\u03bb\u03b1\u03c3\u03bc\u03cc \u03c4\u03b7\u03c2 \u03b2\u03b1\u03ba\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03ae\u03c2 \u03ba\u03bf\u03bb\u03c0\u03af\u03c4\u03b9\u03b4\u03b1\u03c2 \u03c3\u03b5 \u03bc\u03b5\u03c4\u03b5\u03bc\u03bc\u03b7\u03bd\u03bf\u03c0\u03b1\u03c5\u03c3\u03b9\u03b1\u03ba\u03ad\u03c2 \u03b3\u03c5\u03bd\u03b1\u03af\u03ba\u03b5\u03c2 (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B10\" aria-expanded=\"false\" aria-haspopup=\"true\">Cauci et al., 2002<\/a>\u00a0).<\/p>\n<p>\u0397 \u03c3\u03cd\u03bd\u03b8\u03b5\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03bf\u03cd \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03b9\u03ce\u03bc\u03b1\u03c4\u03bf\u03c2 \u03ad\u03c7\u03b5\u03b9 \u03b4\u03b9\u03b5\u03c1\u03b5\u03c5\u03bd\u03b7\u03b8\u03b5\u03af \u03c3\u03b5 \u03bc\u03b9\u03b1 \u03bf\u03bc\u03ac\u03b4\u03b1 87 \u03b3\u03c5\u03bd\u03b1\u03b9\u03ba\u03ce\u03bd, \u03c3\u03c5\u03bc\u03c0\u03b5\u03c1\u03b9\u03bb\u03b1\u03bc\u03b2\u03b1\u03bd\u03bf\u03bc\u03ad\u03bd\u03c9\u03bd 30 \u03c0\u03c1\u03bf\u03b5\u03bc\u03bc\u03b7\u03bd\u03bf\u03c0\u03b1\u03c5\u03c3\u03b9\u03b1\u03ba\u03ce\u03bd, 29 \u03c0\u03b5\u03c1\u03b9\u03b5\u03bc\u03bc\u03b7\u03bd\u03bf\u03c0\u03b1\u03c5\u03c3\u03b9\u03b1\u03ba\u03ce\u03bd \u03ba\u03b1\u03b9 28 \u03bc\u03b5\u03c4\u03b5\u03bc\u03bc\u03b7\u03bd\u03bf\u03c0\u03b1\u03c5\u03c3\u03b9\u03b1\u03ba\u03ce\u03bd \u03b3\u03c5\u03bd\u03b1\u03b9\u03ba\u03ce\u03bd (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B8\" aria-expanded=\"false\" aria-haspopup=\"true\">Brotman et al., 2018<\/a>\u00a0).\u00a0\u039f\u03b9 \u03b2\u03b1\u03ba\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03ad\u03c2 \u03ba\u03bf\u03b9\u03bd\u03cc\u03c4\u03b7\u03c4\u03b5\u03c2 \u03bf\u03bc\u03b1\u03b4\u03bf\u03c0\u03bf\u03b9\u03ae\u03b8\u03b7\u03ba\u03b1\u03bd \u03c3\u03b5 \u03ad\u03be\u03b9 \u03c4\u03cd\u03c0\u03bf\u03c5\u03c2 \u03ba\u03b1\u03c4\u03b1\u03c3\u03c4\u03ac\u03c3\u03b5\u03c9\u03bd (CST), \u03c3\u03c5\u03bc\u03c0\u03b5\u03c1\u03b9\u03bb\u03b1\u03bc\u03b2\u03b1\u03bd\u03bf\u03bc\u03ad\u03bd\u03bf\u03c5 \u03c4\u03bf\u03c5\u00a0<em>Lactobacillus crispatus<\/em>\u00a0\u03c3\u03c4\u03bf CST I, \u03c4\u03bf\u03c5\u00a0<em>Lactobacillus gasseri<\/em>\u00a0\u03c3\u03c4\u03bf CST II,\u00a0<em>\u200b\u200b\u03c4\u03bf\u03c5 Lactobacillus iners<\/em>\u00a0\u03c3\u03c4\u03bf CST III,\u00a0<em>\u03c4\u03bf\u03c5 Lactobacillus jensenii<\/em>\u00a0\u03c3\u03c4\u03bf CST V\u00a0<em>, \u03c4\u03bf\u03c5 Streptococcus<\/em>\u00a0\u03ba\u03b1\u03b9\u00a0<em>\u03c4\u03bf\u03c5 Prevotella \u03c3\u03c4\u03bf CST IV-\u00a0<\/em><em>AtopobiumA<\/em>\u00a0, \u03ba\u03b1\u03b9\u00a0\u03c4\u03bf\u03c5 CST, IV-B (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B40\" aria-expanded=\"false\" aria-haspopup=\"true\">Liu et al., 2013<\/a>\u00a0).\u00a0\u0392\u03c1\u03ad\u03b8\u03b7\u03ba\u03b5 \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ae \u03c3\u03c5\u03c3\u03c7\u03ad\u03c4\u03b9\u03c3\u03b7 \u03bc\u03b5\u03c4\u03b1\u03be\u03cd \u03c4\u03c9\u03bd CST \u03ba\u03b1\u03b9 \u03c4\u03bf\u03c5 \u03c3\u03c4\u03b1\u03b4\u03af\u03bf\u03c5 \u03c4\u03b7\u03c2 \u03b5\u03bc\u03bc\u03b7\u03bd\u03cc\u03c0\u03b1\u03c5\u03c3\u03b7\u03c2, \u03ba\u03b1\u03b8\u03ce\u03c2 \u03ba\u03b1\u03b9 \u03bc\u03b5\u03c4\u03b1\u03be\u03cd \u03c4\u03c9\u03bd CST \u03ba\u03b1\u03b9 \u03c4\u03b7\u03c2 \u03b1\u03b9\u03b4\u03bf\u03b9\u03bf\u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03ae\u03c2 \u03b1\u03c4\u03c1\u03bf\u03c6\u03af\u03b1\u03c2 (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B8\" aria-expanded=\"false\" aria-haspopup=\"true\">Brotman et al., 2018<\/a>\u00a0).<\/p>\n<p>\u039c\u03b9\u03b1 \u03c0\u03c1\u03cc\u03c3\u03c6\u03b1\u03c4\u03b7 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b7 \u03c4\u03c9\u03bd\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B13\" aria-expanded=\"false\" aria-haspopup=\"true\">Cohen et al.\u00a0(2020)<\/a>\u00a0\u03ad\u03c7\u03b5\u03b9 \u03c0\u03c1\u03bf\u03c4\u03b5\u03af\u03bd\u03b5\u03b9 \u03cc\u03c4\u03b9 \u03b7 \u03c7\u03bf\u03c1\u03ae\u03b3\u03b7\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03c3\u03c4\u03b5\u03bb\u03ad\u03c7\u03bf\u03c5\u03c2 CTV-05\u00a0<em>Lactobacillus crispatus<\/em>\u00a0\u03b8\u03b1 \u03bc\u03c0\u03bf\u03c1\u03bf\u03cd\u03c3\u03b5 \u03bd\u03b1 \u03b1\u03c0\u03bf\u03b9\u03ba\u03af\u03c3\u03b5\u03b9 \u03b3\u03c5\u03bd\u03b1\u03af\u03ba\u03b5\u03c2 \u03ba\u03b1\u03b9 \u03bd\u03b1 \u03bc\u03b5\u03b9\u03ce\u03c3\u03b5\u03b9 \u03c4\u03b7 \u03b2\u03b1\u03ba\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03ae \u03ba\u03bf\u03bb\u03c0\u03af\u03c4\u03b9\u03b4\u03b1, \u03cc\u03c4\u03b1\u03bd \u03c7\u03bf\u03c1\u03b7\u03b3\u03b5\u03af\u03c4\u03b1\u03b9 \u03c9\u03c2 \u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03ae \u03b4\u03cc\u03c3\u03b7.<\/p>\n<p>\u03a4\u03bf 2015 \u03bc\u03b9\u03b1 \u03b1\u03bc\u03b5\u03c1\u03b9\u03ba\u03b1\u03bd\u03b9\u03ba\u03ae \u03bc\u03b5\u03bb\u03ad\u03c4\u03b7 \u03b1\u03bd\u03ad\u03bb\u03c5\u03c3\u03b5 \u03c4\u03b7 \u03b4\u03b9\u03b1\u03c6\u03bf\u03c1\u03ac \u03bc\u03b5\u03c4\u03b1\u03be\u03cd \u03c4\u03b7\u03c2 \u03c0\u03b5\u03c1\u03b9\u03b5\u03ba\u03c4\u03b9\u03ba\u03cc\u03c4\u03b7\u03c4\u03b1\u03c2 \u03c3\u03b5 \u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03cc \u03b3\u03bb\u03c5\u03ba\u03bf\u03b3\u03cc\u03bd\u03bf \u03ba\u03b1\u03b9 \u03c4\u03c9\u03bd \u03b5\u03c0\u03b9\u03c0\u03ad\u03b4\u03c9\u03bd \u03c4\u03bf\u03c5 \u03b5\u03af\u03b4\u03bf\u03c5\u03c2\u00a0<em>Lactobacillus<\/em>\u00a0\u03c3\u03b5 \u03b4\u03b5\u03af\u03b3\u03bc\u03b1\u03c4\u03b1 \u03c4\u03c1\u03b1\u03c7\u03b7\u03bb\u03b9\u03ba\u03ae\u03c2 \u03c0\u03bb\u03cd\u03c3\u03b7\u03c2 11 \u03c0\u03c1\u03bf\u03b5\u03bc\u03bc\u03b7\u03bd\u03bf\u03c0\u03b1\u03c5\u03c3\u03b9\u03b1\u03ba\u03ce\u03bd \u03ba\u03b1\u03b9 12 \u03bc\u03b5\u03c4\u03b5\u03bc\u03bc\u03b7\u03bd\u03bf\u03c0\u03b1\u03c5\u03c3\u03b9\u03b1\u03ba\u03ce\u03bd \u03b3\u03c5\u03bd\u03b1\u03b9\u03ba\u03ce\u03bd (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B46\" aria-expanded=\"false\" aria-haspopup=\"true\">Mirmonsef et al., 2015<\/a>\u00a0).\u00a0\u0388\u03c7\u03b5\u03b9 \u03b2\u03c1\u03b5\u03b8\u03b5\u03af \u03cc\u03c4\u03b9 \u03bf\u03b9 \u03bc\u03b5\u03c4\u03b5\u03bc\u03bc\u03b7\u03bd\u03bf\u03c0\u03b1\u03c5\u03c3\u03b9\u03b1\u03ba\u03ad\u03c2 \u03b3\u03c5\u03bd\u03b1\u03af\u03ba\u03b5\u03c2 \u03b5\u03bc\u03c6\u03b1\u03bd\u03af\u03b6\u03bf\u03c5\u03bd \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ac \u03c7\u03b1\u03bc\u03b7\u03bb\u03cc\u03c4\u03b5\u03c1\u03b1 \u03b5\u03c0\u03af\u03c0\u03b5\u03b4\u03b1 \u03b5\u03bb\u03b5\u03cd\u03b8\u03b5\u03c1\u03bf\u03c5 \u03b3\u03bb\u03c5\u03ba\u03bf\u03b3\u03cc\u03bd\u03bf\u03c5 \u03b1\u03c0\u03cc \u03c4\u03b9\u03c2 \u03c0\u03c1\u03bf\u03b5\u03bc\u03bc\u03b7\u03bd\u03bf\u03c0\u03b1\u03c5\u03c3\u03b9\u03b1\u03ba\u03ad\u03c2 \u03b3\u03c5\u03bd\u03b1\u03af\u03ba\u03b5\u03c2, \u03bf\u03b9 \u03bf\u03c0\u03bf\u03af\u03b5\u03c2 \u03bc\u03b5 \u03c4\u03b7 \u03c3\u03b5\u03b9\u03c1\u03ac \u03c4\u03bf\u03c5\u03c2 \u03b5\u03af\u03c7\u03b1\u03bd \u03c5\u03c8\u03b7\u03bb\u03cc\u03c4\u03b5\u03c1\u03b1 \u03b5\u03c0\u03af\u03c0\u03b5\u03b4\u03b1\u00a0<em>\u03b3\u03b1\u03bb\u03b1\u03ba\u03c4\u03bf\u03b2\u03ac\u03ba\u03b9\u03bb\u03bb\u03c9\u03bd<\/em>\u00a0\u03ba\u03b1\u03b9 \u03c7\u03b1\u03bc\u03b7\u03bb\u03cc\u03c4\u03b5\u03c1\u03bf pH \u03c4\u03bf\u03c5 \u03ba\u03cc\u03bb\u03c0\u03bf\u03c5 (\u03bc\u03ad\u03c3\u03bf pH= 4) \u03b1\u03c0\u03cc \u03c4\u03b9\u03c2 \u03bc\u03b5\u03c4\u03b5\u03bc\u03bc\u03b7\u03bd\u03bf\u03c0\u03b1\u03c5\u03c3\u03b9\u03b1\u03ba\u03ad\u03c2 \u03b3\u03c5\u03bd\u03b1\u03af\u03ba\u03b5\u03c2 (\u03b4\u03b9\u03ac\u03bc\u03b5\u03c3\u03bf pH= 4,6) (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B38\" aria-expanded=\"false\" aria-haspopup=\"true\">Lee et al., 2013<\/a>\u00a0).\u00a0\u03a3\u03b5 \u03cc\u03bb\u03b1 \u03c4\u03b1 \u03b4\u03b5\u03af\u03b3\u03bc\u03b1\u03c4\u03b1, \u03ad\u03c7\u03b5\u03b9 \u03b4\u03b5\u03b9\u03c7\u03b8\u03b5\u03af\u00a0\u03b8\u03b5\u03c4\u03b9\u03ba\u03ae \u03c3\u03c5\u03c3\u03c7\u03ad\u03c4\u03b9\u03c3\u03b7 \u03bc\u03b5\u03c4\u03b1\u03be\u03cd \u03c4\u03c9\u03bd \u03b5\u03c0\u03b9\u03c0\u03ad\u03b4\u03c9\u03bd\u00a0<em>L. iners \u03ba\u03b1\u03b9 \u03b3\u03bb\u03c5\u03ba\u03bf\u03b3\u03cc\u03bd\u03bf\u03c5 \u03c3\u03b5 \u03b4\u03b5\u03af\u03b3\u03bc\u03b1\u03c4\u03b1 \u03c4\u03cc\u03c3\u03bf \u03c0\u03c1\u03bf\u03b5\u03bc\u03bc\u03b7\u03bd\u03bf\u03c0\u03b1\u03c5\u03c3\u03b9\u03b1\u03ba\u03ce\u03bd \u03cc\u03c3\u03bf \u03ba\u03b1\u03b9 \u03bc\u03b5\u03c4\u03b5\u03bc\u03bc\u03b7\u03bd\u03bf\u03c0\u03b1\u03c5\u03c3\u03b9\u03b1\u03ba\u03ce\u03bd \u03b3\u03c5\u03bd\u03b1\u03b9\u03ba\u03ce\u03bd.\u00a0<\/em>\u039f\u03bc\u03bf\u03af\u03c9\u03c2, \u03c4\u03b1 \u03b5\u03c0\u03af\u03c0\u03b5\u03b4\u03b1\u00a0<em>L. jensenii<\/em>\u00a0\u03c3\u03c5\u03c3\u03c7\u03b5\u03c4\u03af\u03c3\u03c4\u03b7\u03ba\u03b1\u03bd \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ac \u03bc\u03b5 \u03c4\u03bf \u03b5\u03bb\u03b5\u03cd\u03b8\u03b5\u03c1\u03bf \u03b3\u03bb\u03c5\u03ba\u03bf\u03b3\u03cc\u03bd\u03bf \u03c3\u03b5 \u03cc\u03bb\u03b1 \u03c4\u03b1 \u03b4\u03b5\u03af\u03b3\u03bc\u03b1\u03c4\u03b1.\u00a0<em>\u03a4\u03b1 \u03b5\u03c0\u03af\u03c0\u03b5\u03b4\u03b1 L. iners<\/em>\u00a0\u03b2\u03c1\u03ad\u03b8\u03b7\u03ba\u03b1\u03bd \u03c5\u03c8\u03b7\u03bb\u03cc\u03c4\u03b5\u03c1\u03b1 \u03c3\u03b5 \u03b4\u03b5\u03af\u03b3\u03bc\u03b1\u03c4\u03b1 \u03c0\u03c1\u03bf\u03b5\u03bc\u03bc\u03b7\u03bd\u03bf\u03c0\u03b1\u03c5\u03c3\u03b9\u03b1\u03ba\u03ce\u03bd \u03b3\u03c5\u03bd\u03b1\u03b9\u03ba\u03ce\u03bd, \u03b5\u03bd\u03ce \u03c4\u03b1 \u03b5\u03c0\u03af\u03c0\u03b5\u03b4\u03b1\u00a0<em>L. crispatus<\/em>\u00a0\u03ba\u03b1\u03b9\u00a0<em>L. jensenii<\/em>\u00a0\u03b4\u03b5\u03bd \u03b4\u03b9\u03ad\u03c6\u03b5\u03c1\u03b1\u03bd \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ac \u03bc\u03b5\u03c4\u03b1\u03be\u03cd \u03c4\u03c9\u03bd \u03b4\u03cd\u03bf \u03bf\u03bc\u03ac\u03b4\u03c9\u03bd (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B46\" aria-expanded=\"false\" aria-haspopup=\"true\">Mirmonsef et al., 2015<\/a>\u00a0).<\/p>\n<p>\u03a9\u03c3\u03c4\u03cc\u03c3\u03bf, \u03bf \u03c0\u03b9\u03bf \u03ba\u03bf\u03b9\u03bd\u03cc\u03c2 \u03c4\u03cd\u03c0\u03bf\u03c2 \u03ba\u03bf\u03bb\u03c0\u03af\u03c4\u03b9\u03b4\u03b1\u03c2 \u03c3\u03c4\u03b9\u03c2 \u03bc\u03b5\u03c4\u03b5\u03bc\u03bc\u03b7\u03bd\u03bf\u03c0\u03b1\u03c5\u03c3\u03b9\u03b1\u03ba\u03ad\u03c2 \u03b3\u03c5\u03bd\u03b1\u03af\u03ba\u03b5\u03c2 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b7 \u03b1\u03b5\u03c1\u03cc\u03b2\u03b9\u03b1 \u03ba\u03bf\u03bb\u03c0\u03af\u03c4\u03b9\u03b4\u03b1 (AV), \u03c0\u03bf\u03c5 \u03c7\u03b1\u03c1\u03b1\u03ba\u03c4\u03b7\u03c1\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03bf\u03bd\u00a0<em>Streptococcus spp<\/em>\u00a0\u03c9\u03c2 \u03c4\u03bf \u03ba\u03c5\u03c1\u03af\u03b1\u03c1\u03c7\u03bf \u03b2\u03b1\u03ba\u03c4\u03ae\u03c1\u03b9\u03bf.\u00a0\u0397 AV \u03c0\u03c1\u03bf\u03ba\u03b1\u03bb\u03b5\u03af \u03c3\u03bf\u03b2\u03b1\u03c1\u03ae \u03ba\u03b1\u03c4\u03b1\u03c3\u03c4\u03bf\u03bb\u03ae \u03c4\u03b7\u03c2 \u03c0\u03b1\u03c1\u03b1\u03b3\u03c9\u03b3\u03ae\u03c2 \u03b3\u03b1\u03bb\u03b1\u03ba\u03c4\u03b9\u03ba\u03bf\u03cd \u03bc\u03b5 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ac \u03c7\u03b1\u03c1\u03b1\u03ba\u03c4\u03b7\u03c1\u03b9\u03c3\u03c4\u03b9\u03ba\u03ac \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ac \u03b4\u03b9\u03b1\u03c6\u03bf\u03c1\u03b5\u03c4\u03b9\u03ba\u03ac \u03b1\u03c0\u03cc \u03b5\u03ba\u03b5\u03af\u03bd\u03b1 \u03c4\u03b7\u03c2 \u03b2\u03b1\u03ba\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03ae\u03c2 \u03ba\u03bf\u03bb\u03c0\u03af\u03c4\u03b9\u03b4\u03b1\u03c2.\u00a0\u03a3\u03c4\u03b7\u03bd \u03c0\u03c1\u03b1\u03b3\u03bc\u03b1\u03c4\u03b9\u03ba\u03cc\u03c4\u03b7\u03c4\u03b1, \u03b7 AV \u03c0\u03c1\u03bf\u03ba\u03b1\u03bb\u03b5\u03af \u03bc\u03b9\u03b1 \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ae \u03b1\u03c0\u03cc\u03ba\u03c1\u03b9\u03c3\u03b7 \u03be\u03b5\u03bd\u03b9\u03c3\u03c4\u03ae \u03bc\u03b5 \u03c0\u03b1\u03c1\u03b1\u03b3\u03c9\u03b3\u03ae \u03ba\u03c5\u03c4\u03bf\u03ba\u03b9\u03bd\u03ce\u03bd \u03ba\u03b1\u03b9 \u03c0\u03b1\u03c1\u03bf\u03c5\u03c3\u03af\u03b1 \u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03ce\u03bd \u03bb\u03b5\u03c5\u03ba\u03bf\u03ba\u03c5\u03c4\u03c4\u03ac\u03c1\u03c9\u03bd (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B19\" aria-expanded=\"false\" aria-haspopup=\"true\">Donder et al., 2002<\/a>\u00a0).\u00a0\u03a3\u03c5\u03bd\u03ae\u03b8\u03c9\u03c2 \u03c4\u03bf \u03c7\u03c1\u03ce\u03bc\u03b1 \u03c4\u03b7\u03c2 \u03ad\u03ba\u03ba\u03c1\u03b9\u03c3\u03b7\u03c2 \u03c3\u03c4\u03b7 \u03b2\u03b1\u03ba\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03ae \u03ba\u03bf\u03bb\u03c0\u03af\u03c4\u03b9\u03b4\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c5\u03c0\u03cc\u03bb\u03b5\u03c5\u03ba\u03bf \u03ae \u03b3\u03ba\u03c1\u03b9 \u03ba\u03b1\u03b9 \u03c5\u03b4\u03b1\u03c1\u03ae\u03c2 \u03c3\u03cd\u03c3\u03c4\u03b1\u03c3\u03b7\u03c2, \u03b5\u03bd\u03ce \u03c3\u03c4\u03b7\u03bd AV \u03b5\u03af\u03bd\u03b1\u03b9 \u03ba\u03af\u03c4\u03c1\u03b9\u03bd\u03bf \u03ad\u03c9\u03c2 \u03c0\u03c1\u03ac\u03c3\u03b9\u03bd\u03bf \u03ba\u03b1\u03b9 \u03bc\u03ac\u03bb\u03bb\u03bf\u03bd \u03c0\u03c5\u03ba\u03bd\u03ae \u03b2\u03bb\u03ad\u03bd\u03bd\u03b1.\u00a0\u0391\u03be\u03af\u03b6\u03b5\u03b9 \u03bd\u03b1 \u03c3\u03b7\u03bc\u03b5\u03b9\u03c9\u03b8\u03b5\u03af \u03cc\u03c4\u03b9 \u03b7 \u03c3\u03bf\u03b2\u03b1\u03c1\u03ae \u03ba\u03bf\u03bb\u03c0\u03bf\u03ba\u03bf\u03b9\u03bb\u03b9\u03b1\u03ba\u03ae \u03ba\u03bf\u03bb\u03c0\u03af\u03c4\u03b9\u03b4\u03b1 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03c0\u03c1\u03bf\u03ba\u03b1\u03bb\u03ad\u03c3\u03b5\u03b9 \u03b4\u03c5\u03c3\u03c0\u03b1\u03c1\u03b5\u03cd\u03bd\u03b9\u03b1, \u03b7 \u03bf\u03c0\u03bf\u03af\u03b1 \u03b3\u03b5\u03bd\u03b9\u03ba\u03ac \u03b4\u03b5\u03bd \u03c5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 \u03c3\u03b5 \u03b3\u03c5\u03bd\u03b1\u03af\u03ba\u03b5\u03c2 \u03bc\u03b5 \u03b2\u03b1\u03ba\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03ae \u03ba\u03bf\u03bb\u03c0\u03af\u03c4\u03b9\u03b4\u03b1 (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B17\" aria-expanded=\"false\" aria-haspopup=\"true\">Donder et al., 2017<\/a>\u00a0).<\/p>\n<p>\u0391\u03c5\u03c4\u03ac \u03c4\u03b1 \u03b5\u03c5\u03c1\u03ae\u03bc\u03b1\u03c4\u03b1 \u03c5\u03c0\u03bf\u03c3\u03c4\u03b7\u03c1\u03af\u03b6\u03bf\u03c5\u03bd \u03cc\u03c4\u03b9 \u03b7 \u03c3\u03cd\u03bd\u03b8\u03b5\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03bf\u03cd \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03b9\u03ce\u03bc\u03b1\u03c4\u03bf\u03c2 \u03b1\u03bb\u03bb\u03ac\u03b6\u03b5\u03b9 \u03c6\u03c5\u03c3\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ac \u03c3\u03c4\u03b9\u03c2 \u03bc\u03b5\u03c4\u03b5\u03bc\u03bc\u03b7\u03bd\u03bf\u03c0\u03b1\u03c5\u03c3\u03b9\u03b1\u03ba\u03ad\u03c2 \u03b3\u03c5\u03bd\u03b1\u03af\u03ba\u03b5\u03c2.\u00a0\u0397 \u03c0\u03c4\u03ce\u03c3\u03b7 \u03c4\u03c9\u03bd \u03b5\u03c0\u03b9\u03c0\u03ad\u03b4\u03c9\u03bd \u03c4\u03c9\u03bd \u03bf\u03b9\u03c3\u03c4\u03c1\u03bf\u03b3\u03cc\u03bd\u03c9\u03bd \u03ad\u03c7\u03b5\u03b9 \u03c9\u03c2 \u03b1\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1 \u03c4\u03b7 \u03bc\u03b5\u03af\u03c9\u03c3\u03b7 \u03c4\u03c9\u03bd \u03b5\u03c0\u03b9\u03c0\u03ad\u03b4\u03c9\u03bd LAB, \u03b7 \u03bf\u03c0\u03bf\u03af\u03b1 \u03bc\u03b5 \u03c4\u03b7 \u03c3\u03b5\u03b9\u03c1\u03ac \u03c4\u03b7\u03c2 \u03b5\u03c0\u03b7\u03c1\u03b5\u03ac\u03b6\u03b5\u03b9 \u03c4\u03b7\u03bd \u03b5\u03bc\u03c6\u03ac\u03bd\u03b9\u03c3\u03b7 \u03c3\u03c5\u03bc\u03c0\u03c4\u03c9\u03bc\u03ac\u03c4\u03c9\u03bd \u03b5\u03bc\u03bc\u03b7\u03bd\u03cc\u03c0\u03b1\u03c5\u03c3\u03b7\u03c2 \u03b1\u03c0\u03cc \u03c4\u03bf \u03bf\u03c5\u03c1\u03bf\u03b3\u03b5\u03bd\u03bd\u03b7\u03c4\u03b9\u03ba\u03cc \u03c3\u03cd\u03c3\u03c4\u03b7\u03bc\u03b1, \u03cc\u03c0\u03c9\u03c2 \u03ba\u03c5\u03c1\u03af\u03c9\u03c2 \u03b7 \u03b1\u03b9\u03b4\u03bf\u03b9\u03bf\u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03ae \u03b1\u03c4\u03c1\u03bf\u03c6\u03af\u03b1, \u03b7 \u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03ae \u03be\u03b7\u03c1\u03cc\u03c4\u03b7\u03c4\u03b1 \u03ba\u03b1\u03b9 \u03b7 \u03b4\u03b9\u03b1\u03c4\u03b1\u03c1\u03b1\u03c7\u03ae \u03c4\u03b7\u03c2 \u03c3\u03b5\u03be\u03bf\u03c5\u03b1\u03bb\u03b9\u03ba\u03ae\u03c2 \u03c5\u03b3\u03b5\u03af\u03b1\u03c2.<\/p>\n<p>\u0397 \u03b5\u03c0\u03af\u03b4\u03c1\u03b1\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03c3\u03cd\u03bd\u03b8\u03b5\u03c3\u03b7\u03c2 \u03c4\u03bf\u03c5 \u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03bf\u03cd \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03b9\u03ce\u03bc\u03b1\u03c4\u03bf\u03c2 \u03c3\u03c4\u03b1 \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1 \u03c4\u03b7\u03c2 \u03b5\u03bc\u03bc\u03b7\u03bd\u03cc\u03c0\u03b1\u03c5\u03c3\u03b7\u03c2 \u03c4\u03bf\u03c5 \u03bf\u03c5\u03c1\u03bf\u03b3\u03b5\u03bd\u03bd\u03b7\u03c4\u03b9\u03ba\u03bf\u03cd \u03c3\u03c5\u03c3\u03c4\u03ae\u03bc\u03b1\u03c4\u03bf\u03c2, \u03c4\u03b1 \u03bf\u03b9\u03c3\u03c4\u03c1\u03bf\u03b3\u03cc\u03bd\u03b1 \u03bf\u03c1\u03bf\u03cd \u03ba\u03b1\u03b9 \u03c4\u03bf \u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03cc \u03b3\u03bb\u03c5\u03ba\u03bf\u03b3\u03cc\u03bd\u03bf \u03ad\u03c7\u03b5\u03b9 \u03b4\u03b9\u03b5\u03c1\u03b5\u03c5\u03bd\u03b7\u03b8\u03b5\u03af \u03c3\u03b5 88 \u03bc\u03b5\u03c4\u03b5\u03bc\u03bc\u03b7\u03bd\u03bf\u03c0\u03b1\u03c5\u03c3\u03b9\u03b1\u03ba\u03ad\u03c2 \u03b3\u03c5\u03bd\u03b1\u03af\u03ba\u03b5\u03c2 (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B47\" aria-expanded=\"false\" aria-haspopup=\"true\">Mitchell et al., 2017<\/a>\u00a0).\u00a0\u039c\u03b5\u03c4\u03b1\u03be\u03cd \u03b1\u03c5\u03c4\u03ce\u03bd, \u03c4\u03bf 66% \u03b5\u03af\u03c7\u03b5 \u03b1\u03bd\u03b9\u03c7\u03bd\u03b5\u03c5\u03b8\u03b5\u03af \u03bf\u03c0\u03bf\u03b9\u03bf\u03b4\u03ae\u03c0\u03bf\u03c4\u03b5 \u03b5\u03af\u03b4\u03bf\u03c2\u00a0<em>Lactobacillus<\/em>\u00a0\u03ba\u03b1\u03b9 \u03c4\u03bf 38% \u03b5\u03af\u03c7\u03b5\u00a0\u03ba\u03c5\u03c1\u03af\u03b1\u03c1\u03c7\u03bf \u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03cc \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03af\u03c9\u03bc\u03b1\u00a0<em>Lactobacillus (\u00a0<\/em><a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B47\" aria-expanded=\"false\" aria-haspopup=\"true\">Mitchell et al., 2017<\/a>\u00a0).\u00a0\u03a3\u03c5\u03b3\u03ba\u03b5\u03ba\u03c1\u03b9\u03bc\u03ad\u03bd\u03b1, \u03c4\u03bf 24% \u03c4\u03c9\u03bd \u03b3\u03c5\u03bd\u03b1\u03b9\u03ba\u03ce\u03bd \u03b5\u03af\u03c7\u03b1\u03bd \u03ba\u03b1\u03b9\u00a0<em>L. crispatus<\/em>\u00a0\u03ba\u03b1\u03b9\u00a0<em>L. iners<\/em>\u00a0, \u03c4\u03bf 9% \u03b5\u03af\u03c7\u03b5\u00a0\u03bc\u03cc\u03bd\u03bf\u00a0<em>L. crispatus , \u03c4\u03bf 32% \u03b5\u03af\u03c7\u03b5 \u03bc\u03cc\u03bd\u03bf\u00a0<\/em><em>L. iners<\/em>\u00a0, \u03c4\u03bf 34% \u03b4\u03b5\u03bd \u03b5\u03af\u03c7\u03b5 \u03b5\u03bd\u03c4\u03bf\u03c0\u03b9\u03c3\u03c4\u03b5\u03af \u03ba\u03b1\u03bd\u03ad\u03bd\u03b1 \u03b5\u03af\u03b4\u03bf\u03c2 (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B47\" aria-expanded=\"false\" aria-haspopup=\"true\">Mitchell et al., 2017<\/a>\u00a0).\u00a0\u03a4\u03b1 \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1 \u03c4\u03b7\u03c2 \u03b5\u03bc\u03bc\u03b7\u03bd\u03cc\u03c0\u03b1\u03c5\u03c3\u03b7\u03c2 \u03c4\u03bf\u03c5 \u03bf\u03c5\u03c1\u03bf\u03b3\u03b5\u03bd\u03bd\u03b7\u03c4\u03b9\u03ba\u03bf\u03cd \u03c3\u03c5\u03c3\u03c4\u03ae\u03bc\u03b1\u03c4\u03bf\u03c2 \u03b2\u03c1\u03ad\u03b8\u03b7\u03ba\u03b1\u03bd \u03bd\u03b1 \u03bc\u03b7\u03bd \u03c3\u03c7\u03b5\u03c4\u03af\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03c4\u03b7\u03bd \u03c0\u03b1\u03c1\u03bf\u03c5\u03c3\u03af\u03b1 \u03c3\u03c5\u03b3\u03ba\u03b5\u03ba\u03c1\u03b9\u03bc\u03ad\u03bd\u03c9\u03bd \u03b5\u03b9\u03b4\u03ce\u03bd\u00a0<em>Lactobacillus<\/em>\u00a0(\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B47\" aria-expanded=\"false\" aria-haspopup=\"true\">Mitchell et al., 2017<\/a>\u00a0).\u00a0\u0391\u03be\u03af\u03b6\u03b5\u03b9 \u03bd\u03b1 \u03c3\u03b7\u03bc\u03b5\u03b9\u03c9\u03b8\u03b5\u03af \u03cc\u03c4\u03b9 \u03bf\u03b9 \u03b3\u03c5\u03bd\u03b1\u03af\u03ba\u03b5\u03c2 \u03bc\u03b5 \u03b5\u03c0\u03b9\u03ba\u03c1\u03b1\u03c4\u03bf\u03cd\u03c3\u03b5\u03c2 \u03ba\u03bf\u03b9\u03bd\u03cc\u03c4\u03b7\u03c4\u03b5\u03c2\u00a0<em>Lactobacillus<\/em>\u00a0\u03b1\u03c0\u03bf\u03b4\u03b5\u03af\u03c7\u03b8\u03b7\u03ba\u03b5 \u03cc\u03c4\u03b9 \u03b5\u03af\u03c7\u03b1\u03bd \u03c5\u03c8\u03b7\u03bb\u03cc\u03c4\u03b5\u03c1\u03b7 \u03bc\u03b7 \u03c3\u03c5\u03b6\u03b5\u03c5\u03b3\u03bc\u03ad\u03bd\u03b7 \u03bf\u03b9\u03c3\u03c4\u03c1\u03cc\u03bd\u03b7 \u03bf\u03c1\u03bf\u03cd, \u03b1\u03bb\u03bb\u03ac \u03ba\u03b1\u03bc\u03af\u03b1 \u03b4\u03b9\u03b1\u03c6\u03bf\u03c1\u03ac \u03c3\u03c4\u03b1 \u03b5\u03c0\u03af\u03c0\u03b5\u03b4\u03b1 \u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03bf\u03cd \u03b3\u03bb\u03c5\u03ba\u03bf\u03b3\u03cc\u03bd\u03bf\u03c5 \u03c3\u03b5 \u03c3\u03cd\u03b3\u03ba\u03c1\u03b9\u03c3\u03b7 \u03bc\u03b5 \u03b5\u03ba\u03b5\u03af\u03bd\u03b5\u03c2 \u03bc\u03b5 \u03bc\u03b7\u00a0\u03ba\u03c5\u03c1\u03af\u03b1\u03c1\u03c7\u03b5\u03c2 \u03ba\u03bf\u03b9\u03bd\u03cc\u03c4\u03b7\u03c4\u03b5\u03c2\u00a0<em>Lactobacillus (\u00a0<\/em><a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B47\" aria-expanded=\"false\" aria-haspopup=\"true\">Mitchell et al., 2017<\/a>\u00a0).\u00a0\u03a9\u03c3\u03c4\u03cc\u03c3\u03bf, \u03c5\u03c8\u03b7\u03bb\u03cc\u03c4\u03b5\u03c1\u03b7 \u03bf\u03b9\u03c3\u03c4\u03c1\u03b1\u03b4\u03b9\u03cc\u03bb\u03b7 \u03ba\u03b1\u03b9 \u03bf\u03b9\u03c3\u03c4\u03c1\u03cc\u03bd\u03b7 \u03bf\u03c1\u03bf\u03cd \u03b4\u03b5\u03bd \u03c3\u03c5\u03c3\u03c7\u03b5\u03c4\u03af\u03c3\u03c4\u03b7\u03ba\u03b1\u03bd \u03bf\u03cd\u03c4\u03b5 \u03bc\u03b5 \u03c5\u03c8\u03b7\u03bb\u03cc\u03c4\u03b5\u03c1\u03bf \u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03cc \u03b3\u03bb\u03c5\u03ba\u03bf\u03b3\u03cc\u03bd\u03bf (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B47\" aria-expanded=\"false\" aria-haspopup=\"true\">Mitchell et al., 2017<\/a>\u00a0).<\/p>\n<p>\u03a4\u03bf \u03b5\u03ac\u03bd \u03b7 \u03c7\u03c1\u03ae\u03c3\u03b7 \u03c0\u03c1\u03bf\u03b2\u03b9\u03bf\u03c4\u03b9\u03ba\u03ce\u03bd \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03c3\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae \u03b3\u03b9\u03b1 \u03c4\u03b7 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u03c4\u03c9\u03bd \u03bc\u03b5\u03c4\u03b5\u03bc\u03bc\u03b7\u03bd\u03bf\u03c0\u03b1\u03c5\u03c3\u03b9\u03b1\u03ba\u03ce\u03bd \u03c3\u03c5\u03bc\u03c0\u03c4\u03c9\u03bc\u03ac\u03c4\u03c9\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03ba\u03cc\u03bc\u03b1 \u03c5\u03c0\u03cc \u03b4\u03b9\u03b5\u03c1\u03b5\u03cd\u03bd\u03b7\u03c3\u03b7.\u00a0<em>\u039f\u03b9 \u03b3\u03b1\u03bb\u03b1\u03ba\u03c4\u03bf\u03b2\u03ac\u03ba\u03b9\u03bb\u03bb\u03bf\u03b9<\/em>\u00a0\u03ad\u03c7\u03bf\u03c5\u03bd \u03b1\u03c0\u03bf\u03b4\u03b5\u03b9\u03c7\u03b8\u03b5\u03af \u03cc\u03c4\u03b9 \u03b2\u03b5\u03bb\u03c4\u03b9\u03ce\u03bd\u03bf\u03c5\u03bd \u03c4\u03bf \u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03cc \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03af\u03c9\u03bc\u03b1 \u03c4\u03c9\u03bd \u03b3\u03c5\u03bd\u03b1\u03b9\u03ba\u03ce\u03bd \u03c3\u03c4\u03b7\u03bd \u03b5\u03bc\u03bc\u03b7\u03bd\u03cc\u03c0\u03b1\u03c5\u03c3\u03b7 (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B55\" aria-expanded=\"false\" aria-haspopup=\"true\">Peticevic et al., 2008<\/a>\u00a0).\u00a0\u03a0\u03c1\u03ac\u03b3\u03bc\u03b1\u03c4\u03b9, 72 \u03bc\u03b5\u03c4\u03b5\u03bc\u03bc\u03b7\u03bd\u03bf\u03c0\u03b1\u03c5\u03c3\u03b9\u03b1\u03ba\u03ad\u03c2 \u03b3\u03c5\u03bd\u03b1\u03af\u03ba\u03b5\u03c2 \u03bc\u03b5 \u03c3\u03ba\u03bf\u03c1 Nugent \u03bc\u03b5\u03c4\u03b1\u03be\u03cd 4 \u03ba\u03b1\u03b9 6 \u03c4\u03c5\u03c7\u03b1\u03b9\u03bf\u03c0\u03bf\u03b9\u03ae\u03b8\u03b7\u03ba\u03b1\u03bd \u03c3\u03b5 \u03b4\u03cd\u03bf \u03bf\u03bc\u03ac\u03b4\u03b5\u03c2: 35 \u03b3\u03c5\u03bd\u03b1\u03af\u03ba\u03b5\u03c2 \u03c7\u03c9\u03c1\u03af\u03c3\u03c4\u03b7\u03ba\u03b1\u03bd \u03c3\u03c4\u03b7\u03bd \u03bf\u03bc\u03ac\u03b4\u03b1 \u03c0\u03b1\u03c1\u03ad\u03bc\u03b2\u03b1\u03c3\u03b7\u03c2 \u03ba\u03b1\u03b9 \u03ad\u03bb\u03b1\u03b2\u03b1\u03bd \u03c0\u03c1\u03bf\u03b2\u03b9\u03bf\u03c4\u03b9\u03ba\u03ad\u03c2 \u03ba\u03ac\u03c8\u03bf\u03c5\u03bb\u03b5\u03c2 \u03c0\u03bf\u03c5 \u03c0\u03b5\u03c1\u03b9\u03b5\u03af\u03c7\u03b1\u03bd 2,5 10 9\u00a0<sup>CFU<\/sup>\u00a0\u03ba\u03b1\u03b8\u03b5\u03bc\u03af\u03b1 \u03b1\u03c0\u03cc \u03bb\u03c5\u03bf\u03c6\u03b9\u03bb\u03bf\u03c0\u03bf\u03b9\u03b7\u03bc\u03ad\u03bd\u03bf\u00a0<em>L. rhamnosus<\/em>\u00a0GR-1 \u03ba\u03b1\u03b9\u00a0<em>L. reuteri<\/em>\u00a0RC- 14 \u03ba\u03b1\u03b9 37 \u03b3\u03c5\u03bd\u03b1\u03af\u03ba\u03b5\u03c2 \u03c4\u03c5\u03c7\u03b1\u03b9\u03bf\u03c0\u03bf\u03b9\u03ae\u03b8\u03b7\u03ba\u03b1\u03bd \u03c3\u03c4\u03b7\u03bd \u03bf\u03bc\u03ac\u03b4\u03b1 \u03b5\u03bb\u03ad\u03b3\u03c7\u03bf\u03c5 \u03ba\u03b1\u03b9 \u03ad\u03bb\u03b1\u03b2\u03b1\u03bd \u03b1\u03c0\u03cc \u03c4\u03bf\u03c5 \u03c3\u03c4\u03cc\u03bc\u03b1\u03c4\u03bf\u03c2 \u03b5\u03b9\u03ba\u03bf\u03bd\u03b9\u03ba\u03cc \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03bf \u03bc\u03af\u03b1 \u03c6\u03bf\u03c1\u03ac \u03c4\u03b7\u03bd \u03b7\u03bc\u03ad\u03c1\u03b1 \u03b3\u03b9\u03b1 14 \u03b7\u03bc\u03ad\u03c1\u03b5\u03c2.\u00a0\u0397 \u03b4\u03b9\u03ac\u03bc\u03b5\u03c3\u03b7 \u03b4\u03b9\u03b1\u03c6\u03bf\u03c1\u03ac \u03c3\u03c4\u03b9\u03c2 \u03b2\u03b1\u03b8\u03bc\u03bf\u03bb\u03bf\u03b3\u03af\u03b5\u03c2 Nugent \u03bc\u03b5\u03c4\u03b1\u03be\u03cd \u03c4\u03b7\u03c2 \u03b2\u03b1\u03c3\u03b9\u03ba\u03ae\u03c2 \u03b3\u03c1\u03b1\u03bc\u03bc\u03ae\u03c2 \u03ba\u03b1\u03b9 \u03c4\u03bf\u03c5 \u03c4\u03ad\u03bb\u03bf\u03c5\u03c2 \u03c4\u03b7\u03c2 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b7\u03c2 \u03ae\u03c4\u03b1\u03bd 3 \u03c3\u03c4\u03b7\u03bd \u03bf\u03bc\u03ac\u03b4\u03b1 \u03c0\u03b1\u03c1\u03ad\u03bc\u03b2\u03b1\u03c3\u03b7\u03c2 \u03ba\u03b1\u03b9 0 \u03c3\u03c4\u03b7\u03bd \u03bf\u03bc\u03ac\u03b4\u03b1 \u03b5\u03bb\u03ad\u03b3\u03c7\u03bf\u03c5 (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B55\" aria-expanded=\"false\" aria-haspopup=\"true\">Peticevic et al., 2008<\/a>\u00a0), \u03bf\u03b4\u03b7\u03b3\u03ce\u03bd\u03c4\u03b1\u03c2 \u03ad\u03c4\u03c3\u03b9 \u03c3\u03c4\u03b7\u03bd \u03bf\u03c5\u03c3\u03b9\u03b1\u03c3\u03c4\u03b9\u03ba\u03ae \u03b2\u03b5\u03bb\u03c4\u03af\u03c9\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03ae\u03c2 \u03c7\u03bb\u03c9\u03c1\u03af\u03b4\u03b1\u03c2 \u03c4\u03c9\u03bd \u03bc\u03b5\u03c4\u03b5\u03bc\u03bc\u03b7\u03bd\u03bf\u03c0\u03b1\u03c5\u03c3\u03b9\u03b1\u03ba\u03ce\u03bd \u03b3\u03c5\u03bd\u03b1\u03b9\u03ba\u03ce\u03bd \u03ba\u03b1\u03b9 \u03c0\u03b1\u03c1\u03ad\u03c7\u03bf\u03bd\u03c4\u03b1\u03c2 \u03c3\u03c4\u03bf\u03b9\u03c7\u03b5\u03af\u03b1 \u03b3\u03b9\u03b1 \u03c4\u03b7 \u03c7\u03c1\u03ae\u03c3\u03b7 \u03c0\u03c1\u03bf\u03b2\u03b9\u03bf\u03c4\u03b9\u03ba\u03ce\u03bd \u03b1\u03c0\u03cc \u03c4\u03bf \u03c3\u03c4\u03cc\u03bc\u03b1 \u03c9\u03c2 \u03c0\u03b9\u03b8\u03b1\u03bd\u03ae \u03b5\u03bd\u03b1\u03bb\u03bb\u03b1\u03ba\u03c4\u03b9\u03ba\u03ae \u03c0\u03c1\u03bf\u03c3\u03ad\u03b3\u03b3\u03b9\u03c3\u03b7 \u03b3\u03b9\u03b1 \u03c4\u03b7\u03bd \u03b1\u03c0\u03bf\u03ba\u03b1\u03c4\u03ac\u03c3\u03c4\u03b1\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03c6\u03c5\u03c3\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ae\u03c2 \u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03ae\u03c2 \u03c7\u03bb\u03c9\u03c1\u03af\u03b4\u03b1\u03c2 (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B55\" aria-expanded=\"false\" aria-haspopup=\"true\">Peticevic et al., 2008<\/a>\u00a0).<\/p>\n<p>\u0397 \u03b5\u03c0\u03af\u03b4\u03c1\u03b1\u03c3\u03b7 \u03b5\u03be\u03b1\u03b9\u03c1\u03b5\u03c4\u03b9\u03ba\u03ac \u03c7\u03b1\u03bc\u03b7\u03bb\u03ae\u03c2 \u03b4\u03cc\u03c3\u03b7\u03c2 \u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03ce\u03bd \u03b4\u03b9\u03c3\u03ba\u03af\u03c9\u03bd \u03bf\u03b9\u03c3\u03c4\u03c1\u03b9\u03cc\u03bb\u03b7\u03c2 (0,03 mg) \u03ba\u03b1\u03b9\u00a0<em>Lactobacillus acidophilus<\/em>\u00a0\u03c3\u03b5 \u03c3\u03cd\u03b3\u03ba\u03c1\u03b9\u03c3\u03b7 \u03bc\u03b5 \u03b5\u03b9\u03ba\u03bf\u03bd\u03b9\u03ba\u03cc \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03bf \u03ad\u03c7\u03b5\u03b9 \u03b4\u03b9\u03b5\u03c1\u03b5\u03c5\u03bd\u03b7\u03b8\u03b5\u03af \u03c3\u03b5 87 \u03bc\u03b5\u03c4\u03b5\u03bc\u03bc\u03b7\u03bd\u03bf\u03c0\u03b1\u03c5\u03c3\u03b9\u03b1\u03ba\u03ad\u03c2 \u03b3\u03c5\u03bd\u03b1\u03af\u03ba\u03b5\u03c2.\u00a0\u0397 \u03b5\u03bd\u03c3\u03c4\u03ac\u03bb\u03b1\u03be\u03b7 \u03b3\u03b1\u03bb\u03b1\u03ba\u03c4\u03bf\u03b2\u03b1\u03ba\u03af\u03bb\u03bb\u03c9\u03bd \u03ba\u03b1\u03b9 \u03b5\u03be\u03b1\u03b9\u03c1\u03b5\u03c4\u03b9\u03ba\u03ac \u03c7\u03b1\u03bc\u03b7\u03bb\u03ae\u03c2 \u03b4\u03cc\u03c3\u03b7\u03c2 \u03bf\u03b9\u03c3\u03c4\u03c1\u03b9\u03cc\u03bb\u03b7\u03c2 \u03b2\u03c1\u03ad\u03b8\u03b7\u03ba\u03b5 \u03cc\u03c4\u03b9 \u03b2\u03b5\u03bb\u03c4\u03b9\u03ce\u03bd\u03b5\u03b9 \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ac \u03c4\u03b1 \u03b1\u03b9\u03b4\u03bf\u03b9\u03bf\u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03ac \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1 \u03c3\u03b5 \u03c4\u03ad\u03c4\u03bf\u03b9\u03b5\u03c2 \u03b3\u03c5\u03bd\u03b1\u03af\u03ba\u03b5\u03c2 (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B35\" aria-expanded=\"false\" aria-haspopup=\"true\">Jaisamrarn et al., 2013<\/a>\u00a0).<\/p>\n<p class=\"p p-last\">\u039c\u03b9\u03b1 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03b4\u03bf\u03ba\u03b9\u03bc\u03ae \u03c3\u03b5 60 \u03bc\u03b5\u03c4\u03b5\u03bc\u03bc\u03b7\u03bd\u03bf\u03c0\u03b1\u03c5\u03c3\u03b9\u03b1\u03ba\u03ad\u03c2 \u03b3\u03c5\u03bd\u03b1\u03af\u03ba\u03b5\u03c2 (\u03b7\u03bb\u03b9\u03ba\u03af\u03b1\u03c2 40 \u03ad\u03c9\u03c2 60 \u03b5\u03c4\u03ce\u03bd), \u03bf\u03b9 \u03bf\u03c0\u03bf\u03af\u03b5\u03c2 \u03c4\u03c5\u03c7\u03b1\u03af\u03b1 \u03ad\u03bb\u03b1\u03b2\u03b1\u03bd \u03b1\u03c0\u03cc \u03c4\u03bf\u03c5 \u03c3\u03c4\u03cc\u03bc\u03b1\u03c4\u03bf\u03c2 \u03b9\u03c3\u03bf\u03c6\u03bb\u03b1\u03b2\u03cc\u03bd\u03b7 (150 mg \u03be\u03b7\u03c1\u03cc \u03b5\u03ba\u03c7\u03cd\u03bb\u03b9\u03c3\u03bc\u03b1 \u03b3\u03bb\u03c5\u03ba\u03af\u03bd\u03b7\u03c2 max) \u03bc\u03cc\u03bd\u03bf \u03ae \u03b9\u03c3\u03bf\u03c6\u03bb\u03b1\u03b2\u03cc\u03bd\u03b7 \u03c3\u03c5\u03bd \u03c0\u03c1\u03bf\u03b2\u03b9\u03bf\u03c4\u03b9\u03ba\u03ac (\u00a0<em>L. acidophilus, L. casei, Lactococcus lactis, Bifidobacterium bifidum ,<\/em>\u00a0\u03ba\u03b1\u03b9\u00a0<em>Bifidobacterium lactis<\/em>\u00a0), \u03ae \u03bf\u03c1\u03bc\u03bf\u03bd\u03b9\u03ba\u03ae \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 (1 mg \u03bf\u03b9\u03c3\u03c4\u03c1\u03b1\u03b4\u03b9\u03cc\u03bb\u03b7\u03c2 \u03ba\u03b1\u03b9 0,5 mg \u03bf\u03be\u03b9\u03ba\u03ae\u03c2 \u03bd\u03bf\u03c1\u03b5\u03b8\u03b9\u03c3\u03c4\u03b5\u03c1\u03cc\u03bd\u03b7\u03c2) \u03ad\u03c7\u03b5\u03b9 \u03b4\u03b5\u03af\u03be\u03b5\u03b9 \u03cc\u03c4\u03b9 \u03bc\u03b5\u03c4\u03ac \u03b1\u03c0\u03cc 16 \u03b5\u03b2\u03b4\u03bf\u03bc\u03ac\u03b4\u03b5\u03c2 \u03b7 \u03bf\u03bc\u03ac\u03b4\u03b1 \u03bf\u03c1\u03bc\u03bf\u03bd\u03b9\u03ba\u03ae\u03c2 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1\u03c2 \u03b5\u03bc\u03c6\u03ac\u03bd\u03b9\u03c3\u03b5 \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03bf \u03b1\u03c1\u03b9\u03b8\u03bc\u03cc \u03b3\u03b1\u03bb\u03b1\u03ba\u03c4\u03bf\u03b2\u03b1\u03ba\u03af\u03bb\u03bb\u03c9\u03bd \u03c3\u03c4\u03bf\u03bd \u03ba\u03cc\u03bb\u03c0\u03bf, \u03c0\u03b1\u03c1\u03cc\u03bc\u03bf\u03b9\u03bf \u03bc\u03b5 \u03b1\u03c5\u03c4\u03cc\u03bd \u03c0\u03bf\u03c5 \u03c0\u03b1\u03c1\u03b1\u03c4\u03b7\u03c1\u03ae\u03b8\u03b7\u03ba\u03b5 \u03c3\u03c4\u03b7\u03bd \u03c0\u03c1\u03bf\u03b5\u03bc\u03bc\u03b7\u03bd\u03bf\u03c0\u03b1\u03c5\u03c3\u03b9\u03b1\u03ba\u03ae \u03ba\u03b1\u03c4\u03ac\u03c3\u03c4\u03b1\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03bc\u03b5\u03af\u03c9\u03c3\u03b7 \u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03cc PH;\u00a0\u0391\u03bd\u03c4\u03af\u03b8\u03b5\u03c4\u03b1, \u03b4\u03b5\u03bd \u03b2\u03c1\u03ad\u03b8\u03b7\u03ba\u03b5 \u03ba\u03b1\u03bc\u03af\u03b1 \u03b1\u03bb\u03bb\u03b1\u03b3\u03ae \u03c3\u03c4\u03b7\u03bd \u03c4\u03b9\u03bc\u03ae \u03c4\u03bf\u03c5 pH \u03c3\u03c4\u03b7\u03bd \u03bf\u03bc\u03ac\u03b4\u03b1 \u03c4\u03c9\u03bd \u03b9\u03c3\u03bf\u03c6\u03bb\u03b1\u03b2\u03bf\u03bd\u03ce\u03bd \u03ba\u03b1\u03b9 \u03c3\u03c4\u03b7\u03bd \u03bf\u03bc\u03ac\u03b4\u03b1 \u03b9\u03c3\u03bf\u03c6\u03bb\u03b1\u03b2\u03cc\u03bd\u03b7\u03c2 \u03c3\u03c5\u03bd \u03c0\u03c1\u03bf\u03b2\u03b9\u03bf\u03c4\u03b9\u03ba\u03ce\u03bd (\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B63\" aria-expanded=\"false\" aria-haspopup=\"true\">Ribeiro et al., 2018<\/a>\u00a0).\u00a0\u039c\u03b9\u03b1 \u03c0\u03c1\u03cc\u03c3\u03c6\u03b1\u03c4\u03b7 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b7 \u03c4\u03c9\u03bd\u00a0<a class=\" bibr popnode\" role=\"button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8290858\/#B13\" aria-expanded=\"false\" aria-haspopup=\"true\">Cohen et al.\u00a0(2020)<\/a> \u03c0\u03bf\u03c5 \u03b4\u03b9\u03b5\u03be\u03ae\u03c7\u03b8\u03b7 \u03c3\u03c4\u03b9\u03c2 228 \u03c0\u03c1\u03bf\u03b5\u03bc\u03bc\u03b7\u03bd\u03bf\u03c0\u03b1\u03c5\u03c3\u03b9\u03b1\u03ba\u03ad\u03c2 \u03c5\u03c0\u03bf\u03b4\u03b5\u03af\u03be\u03b5\u03b9\u03c2 \u03cc\u03c4\u03b9 \u03b7 \u03ba\u03b1\u03b8\u03b7\u03bc\u03b5\u03c1\u03b9\u03bd\u03ae \u03c7\u03bf\u03c1\u03ae\u03b3\u03b7\u03c3\u03b7 \u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03ae\u03c2 \u03b4\u03cc\u03c3\u03b7\u03c2 Lactobacillus crispatus, \u03bc\u03b5\u03c4\u03ac \u03b1\u03c0\u03cc \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u03bc\u03b5 \u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03ae \u03bc\u03b5\u03c4\u03c1\u03bf\u03bd\u03b9\u03b4\u03b1\u03b6\u03cc\u03bb\u03b7, \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03bc\u03b5\u03b9\u03ce\u03c3\u03b5\u03b9 \u03c4\u03b7\u03bd \u03c5\u03c0\u03bf\u03c4\u03c1\u03bf\u03c0\u03ae \u03c4\u03b7\u03c2 \u03b2\u03b1\u03ba\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03ae\u03c2 \u03ba\u03bf\u03bb\u03c0\u03af\u03c4\u03b9\u03b4\u03b1\u03c2 \u03bc\u03b5\u03c4\u03ac \u03b1\u03c0\u03cc 12 \u03b5\u03b2\u03b4\u03bf\u03bc\u03ac\u03b4\u03b5\u03c2.<\/p>\n<\/div>\n<div id=\"s5\" class=\"tsec sec\">\n<p class=\"p p-first-last\">\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div><\/div><\/div><\/div><\/div><\/div><div id=\"pg-11945-1\"  class=\"panel-grid panel-no-style\" ><div id=\"pgc-11945-1-0\"  class=\"panel-grid-cell panel-grid-cell-empty\" ><\/div><div id=\"pgc-11945-1-1\"  class=\"panel-grid-cell panel-grid-cell-mobile-last\" ><div id=\"panel-11945-1-1-0\" class=\"so-panel widget widget_sow-button panel-first-child panel-last-child\" data-index=\"2\" ><div\n\t\t\t\n\t\t\tclass=\"so-widget-sow-button so-widget-sow-button-flat-b264fac09b79-11945\"\n\t\t\t\n\t\t><div class=\"ow-button-base ow-button-align-center\"\n>\n\t\t\t<a\n\t\t\t\t\thref=\"https:\/\/doctorvasiliadis.gr\/?page_id=7419\"\n\t\t\t\t\tclass=\"sowb-button ow-icon-placement-left ow-button-hover\" \t>\n\t\t<span>\n\t\t\t\n\t\t\t<strong>\u03b5\u03c0\u03b9\u03c3\u03c4\u03c1\u03bf\u03c6\u03ae<\/strong>\t\t<\/span>\n\t\t\t<\/a>\n\t<\/div>\n<\/div><\/div><\/div><div id=\"pgc-11945-1-2\"  class=\"panel-grid-cell panel-grid-cell-empty\" ><\/div><\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>Front Cell Infect Microbiol.\u00a02021;\u00a011: 686167. \u0394\u03b7\u03bc\u03bf\u03c3\u03b9\u03b5\u03cd\u03b8\u03b7\u03ba\u03b5 \u03c3\u03c4\u03bf \u03b4\u03b9\u03b1\u03b4\u03af\u03ba\u03c4\u03c5\u03bf 2021, 6 \u0399\u03bf\u03c5\u03bb\u03af\u03bf\u03c5. doi:10.3389\/fcimb.2021.686167 \u03a4\u03bf \u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03cc \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03af\u03c9\u03bc\u03b1: \u0388\u03bd\u03b1\u03c2 \u03bc\u03b1\u03ba\u03c1\u03cd\u03c2 \u03bf\u03c5\u03c1\u03bf\u03b3\u03b5\u03bd\u03bd\u03b7\u03c4\u03b9\u03ba\u03cc\u03c2 \u03b1\u03c0\u03bf\u03b9\u03ba\u03b9\u03c3\u03bc\u03cc\u03c2 \u03c3\u03b5 \u03cc\u03bb\u03b7 \u03c4\u03b7 \u03b6\u03c9\u03ae \u03c4\u03b7\u03c2 \u03b3\u03c5\u03bd\u03b1\u03af\u03ba\u03b1\u03c2 \u03b4\u03b9\u03b1\u03b2\u03ac\u03c3\u03c4\u03b5 \u03b5\u03b4\u03ce \u03c4\u03bf \u0391\u03b3\u03b3\u03bb\u03b9\u03ba\u03cc \u03ac\u03c1\u03b8\u03c1\u03bf\u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0\u00a0 \u03a3\u03b1\u03c2 \u03c0\u03b1\u03c1\u03b1\u03b8\u03ad\u03c4\u03bf\u03c5\u03bc\u03b5 \u03c4\u03b7\u03bd \u0395\u03bb\u03bb\u03b7\u03bd\u03b9\u03ba\u03ae \u03b1\u03c0\u03cc\u03b4\u03bf\u03c3\u03b7 \u0395\u03b9\u03c3\u03b1\u03b3\u03c9\u03b3\u03ae \u03a4\u03bf \u03ba\u03bf\u03bb\u03c0\u03b9\u03ba\u03cc \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03af\u03c9\u03bc\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03ad\u03bd\u03b1 \u03c0\u03bf\u03bb\u03cd\u03c0\u03bb\u03bf\u03ba\u03bf \u03bf\u03b9\u03ba\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03cc \u03c3\u03cd\u03c3\u03c4\u03b7\u03bc\u03b1 \u03c0\u03bf\u03c5 \u03c0\u03b5\u03c1\u03b9\u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03b5\u03b9 [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-11945","page","type-page","status-publish","hentry","post"],"_links":{"self":[{"href":"https:\/\/doctorvasiliadis.gr\/index.php?rest_route=\/wp\/v2\/pages\/11945","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/doctorvasiliadis.gr\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/doctorvasiliadis.gr\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/doctorvasiliadis.gr\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/doctorvasiliadis.gr\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=11945"}],"version-history":[{"count":0,"href":"https:\/\/doctorvasiliadis.gr\/index.php?rest_route=\/wp\/v2\/pages\/11945\/revisions"}],"wp:attachment":[{"href":"https:\/\/doctorvasiliadis.gr\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=11945"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}